Interferon alfa-n3 is used to treat genital warts in adults. interferon alfa-n3 is for use only on the outside of the body.

Interferon alfa-n3 is usually given after other treatments have failed.

Interferon alfa-n3 may also be used for purposes not listed in this medication guide.

Call your doctor if your genital warts do not completely clear up within 3 months after your last injection of interferon alfa-n3.

Interferon alfa-n3 is injected directly into each genital wart lesion, usually given 2 times per week for up to 8 weeks.

A healthcare provider will give you this injection.

Your lesions may only partially clear up after 8 weeks, but you may notice improvement even after your treatment ends.

Tell your doctor if your warts do not completely clear up within 3 months after your last injection.

Usual Adult Dose for Condylomata Acuminata:

Refractory or recurring external condylomata acuminata:
0.05 mL (250,000 international units) per wart, injected intralesionally 2 times a week for up to 8 weeks
-The maximum recommended dose per treatment session is 0.5 mL (2.5 million international units).
-Therapy should not be repeated for at least 3 months after the initial 8-week course of therapy (unless existing warts grow or new warts appear).

Use: For the intralesional treatment of refractory or recurring external condylomata acuminata

Tell your doctor if you have ever had:

• low white blood cell (WBC) counts;

• an autoimmune disorder such as rheumatoid arthritis, lupus, or psoriasis;

• liver or kidney disease;

• depression or mental illness;

• heart problems; or

• a thyroid disorder.

Tell your doctor if you are pregnant or breastfeeding.

Call your doctor for instructions if you miss an appointment for your interferon alfa-n3 injection.

In a medical setting an overdose would be treated quickly.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Get emergency medical help if you have signs of an allergic reaction (hives, chest tightness, wheezing, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Interferon alfa-n3 may cause serious side effects. Call your doctor at once if you have:

• chest pain or pressure;

• a light-headed feeling, like you might pass out;

• blurred vision;

• a hoarse voice; or

• low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough.

Common side effects of interferon alfa-n3 may include:

• headache;

• vomiting;

• fever, chills, flu-like symptoms; or

• joint or muscle pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Other drugs may affect interferon alfa-n3, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.