Latest Drugs, Latest Approval in Platelet aggregation inhibitors

What are Platelet aggregation inhibitors?

Platelet aggregation inhibitors work in different places of the clotting cascade and prevent platelet adhesion, therefore no clot formation.

Aspirin, the most commonly used antiplatelet drug changes the balance between prostacyclin (which inhibits platelet aggregation) and thromboxane (that promotes aggregation). It irreversibly inhibits the enzyme cyclo-oxygenase, which leads to reduction in thromboxane synthesis in platelets and prostacyclin in vascular endothelial cells. The vascular endothelium recovers and can synthesize more prostacyclin but thromboxane synthesis only recovers after new platelets are formed.

Platelet aggregation inhibitors are used acutely in myocardial infarction, atrial fibrillation, following coronary bypass, angioplasty and stenting. It is also used as prophylaxis to prevent myocardial infarction and stroke.

Name Updated
Caplacizumab (Caplacizumab [ kap-la-siz-ue-mab ]) 16-Aug-2023
Dipyridamole (Dipyridamole (oral/injection) [ dye-pir-id-a-mole ]) 15-Aug-2023
Miniprin (Aspirin (oral) [ as-pir-in ]) 13-Aug-2023
Aspirin (rectal) (Aspirin (rectal) [ as-pi-rin ]) 13-Aug-2023
Aspirin and omeprazole (Aspirin and omeprazole [ as-pir-in-and-oh-mep-ra-zole ]) 13-Aug-2023
Aspirin and dipyridamole (Aspirin and dipyridamole [ as-pi-rin-and-dye-peer-id-a-mole ]) 13-Aug-2023
Ticagrelor (Ticagrelor [ tye-ka-grel-or ]) 12-Aug-2023
Prasugrel (Prasugrel [ pra-soo-grel ]) 12-Aug-2023
Cilostazol (Cilostazol [ sye-loe-sta-zol ]) 11-Aug-2023
Vazalore (Aspirin (oral) [ as-pir-in ]) 05-Aug-2023
Yosprala (Aspirin and omeprazole [ as-pir-in-and-oh-mep-ra-zole ]) 05-Aug-2023
Pravigard pac (Aspirin and pravastatin [ as-pir-in-and-prav-a-stat-in ]) 13-Jul-2023
Pletal (Cilostazol [ sye-loe-sta-zol ]) 13-Jul-2023
Persantine (Dipyridamole (oral/injection) [ dye-pir-id-a-mole ]) 13-Jul-2023
Effient (Prasugrel [ pra-soo-grel ]) 13-Jul-2023
Durlaza (Aspirin (oral) [ as-pir-in ]) 13-Jul-2023
Cablivi (Caplacizumab [ kap-la-siz-ue-mab ]) 13-Jul-2023
Bayer plus (Aspirin (oral) [ as-pir-in ]) 12-Jul-2023
Aspir-low (Aspirin (oral) [ as-pir-in ]) 12-Jul-2023
Aspi-cor (Aspirin (oral) [ as-pir-in ]) 12-Jul-2023
Arthritis pain (Aspirin (oral) [ as-pir-in ]) 12-Jul-2023
Plavix (Clopidogrel [ kloe-pid-oh-grel ]) 11-Jul-2023
Ecotrin (Aspirin (oral) [ as-pir-in ]) 10-Jul-2023
Clopidogrel (Clopidogrel [ kloe-pid-oh-grel ]) 10-Jul-2023
Brilinta (Ticagrelor) 10-Jul-2023
Aspirin (Aspirin (oral) [ as-pir-in ]) 10-Jul-2023