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Home > Drugs > Miscellaneous cardiovascular agents > Cilostazol
Miscellaneous cardiovascular agents

Cilostazol

https://themeditary.com/drug/cilostazol-4954.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Aug 11, 2023  Additional Content by TheMediTary.Com

Generic name: cilostazol [ sye-loe-sta-zol ]

Drug class: Miscellaneous cardiovascular agents, Platelet aggregation inhibitors

Dosage form: oral tablet (100 mg; 50 mg)

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Pletal

Contents
Uses Warnings Before Taking Dosage Side effects Interactions
  • Cilostazol (Cilostazol [ sye-loe-sta-zol ])-7230 93-50 mg-White-Four-sided Cilostazol 50 mg (7230 93)
  • Cilostazol (Cilostazol [ sye-loe-sta-zol ])-7231 93-100 mg-White-Round Cilostazol 100 mg (7231 93)
  • Cilostazol (Cilostazol [ sye-loe-sta-zol ])-E 223-100 mg-White-Round Cilostazol 100 mg (E 223)
  • Cilostazol (Cilostazol [ sye-loe-sta-zol ])-E 123-50 mg-White-Round Cilostazol 50 mg (E 123)
  • View all images

What is Cilostazol?

Cilostazol is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). Cilostazol dilates arteries that supply blood to your legs. Cilostazol also improves circulation by keeping platelets in the blood from sticking together and clotting.

Cilostazol is used to treat the symptoms of intermittent claudication. This condition causes reduced blood flow to the legs, leading to pain while walking. Cilostazol improves your ability to walk longer distances without pain.

Cilostazol may also be used for purposes not listed in this medication guide.

Warnings

Do not take cilostazol if you have heart failure of any kind.

How should I take Cilostazol

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Cilostazol is usually taken twice a day on an empty stomach, at least 30 minutes before or 2 hours after breakfast or dinner.

Take the medicine at the same time each day.

It may take up to 12 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 3 months of treatment.

Store at room temperature away from moisture and heat.

Dosing information

Usual Adult Dose for Intermittent Claudication:

100 mg orally twice a day at least 30 minutes before or 2 hours after breakfast and dinner

Comments:
-Patients may respond as early as 2 to 4 weeks after initiation of therapy, but treatment for up to 12 weeks may be required before a beneficial effect is experienced.
-If symptoms remain unimproved after 3 months, discontinue this drug.

Use: Reduction of symptoms of intermittent claudication, as demonstrated by an increased walking distance.

Detailed Cilostazol dosage information
Cilostazol Dosage information (more detail)

Before Taking

You should not take cilostazol if you have heart failure of any kind. Cilostazol can make this condition worse.

Tell your doctor if you have ever had:

  • bleeding problems;

  • liver or kidney disease;

  • a heart attack or stroke; or

  • if you smoke.

It is not known whether cilostazol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using cilostazol.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

What should I avoid while using Cilostazol?

Grapefruit may interact with cilostazol and lead to unwanted side effects. Avoid the use of grapefruit products.

Cilostazol side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Cilostazol may cause serious side effects. Call your doctor at once if you have:

  • chest pain, pounding heartbeats or fluttering in your chest;

  • a light-headed feeling, like you might pass out;

  • fever, chills, sore throat, mouth sores; or

  • easy bruising, unusual bleeding, purple or red spots under your skin.

Common side effects of cilostazol may include:

  • diarrhea, abnormal bowel movements;

  • headache; or

  • fast or pounding heartbeats.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Cilostazol Side Effects

What other drugs will affect Cilostazol?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect cilostazol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

More about Cilostazol (Cilostazol [ sye-loe-sta-zol ])

Dosage information
Cilostazol Side Effects
During pregnancy
Drug images
Side effects
Drug class: Miscellaneous cardiovascular agents

Related treatment guides

Intermittent Claudication
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions
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