Generic name: Fosnetupitant and palonosetron (injection)
Pregnancy & Lactation: Risk data not available
What is Akynzeo For Injection?
Fosnetupitant and palonosetron is a combination medicine used to help prevent nausea and vomiting caused by chemotherapy. This medicine is given together with a steroid called dexamethasone.
Fosnetupitant and palonosetron helps prevent nausea and vomiting that occurs both during chemotherapy and later on (delayed nausea and vomiting).
Fosnetupitant and palonosetron may also be used for purposes not listed in this medication guide.
Warnings
Fosnetupitant and palonosetron may harm an unborn baby. Tell your doctor if you become pregnant.
Tell your doctor if you have ever had:
- liver or kidney disease; or
- an allergic reaction to a medicine for nausea or vomiting, such as dolasetron (Anzemet), ondansetron (Zofran), or palonosetron (Aloxi).
Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, or serious infections. These medicines may interact with fosnetupitant and palonosetron and cause a serious condition called serotonin syndrome.
You should not breast-feed while using this medicine.
Fosnetupitant and palonosetron is not approved for use by anyone younger than 18 years old.
How should I use Akynzeo For Injection
Use Akynzeo For Injection (Fosnetupitant And Palonosetron (Injection)) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
This medicine is given ahead of time and will not treat nausea or vomiting you already have.
About 30 minutes before chemotherapy, a healthcare provider will give you fosnetupitant and palonosetron as an infusion into a vein.
You will also take dexamethasone 30 minutes before chemotherapy, and you may need to keep taking dexamethasone for 3 days afterward. Follow your doctor's dosing instructions very carefully.
Fosnetupitant and palonosetron is used as a single injection and does not have a daily dosing schedule.
Akynzeo For Injection side effects
Get emergency medical help if you have signs of an allergic reaction: hives; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Common side effects may include:
- headache;
- feeling weak or tired;
- skin redness; or
- upset stomach, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Akynzeo For Injection?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.