In the US, Amitriptyline (amitriptyline systemic) is a member of the drug class tricyclic antidepressants and is used to treat Anxiety and Stress, Burning Mouth Syndrome, Chronic Myofascial Pain, Cough, Cyclic Vomiting Syndrome, Depression, Depressive Psychosis, Dysautonomia, Fibromyalgia, Hyperhidrosis, Insomnia, Interstitial Cystitis, Irritable Bowel Syndrome, Migraine Prevention, Neuropathic Pain, Neurotic Depression, Pain, Persistent Depressive Disorder, Post Traumatic Stress Disorder, Pudendal Neuralgia, Reflex Sympathetic Dystrophy Syndrome, Somatoform Pain Disorder, Urinary Incontinence and Vulvodynia.

US matches:

• Amitriptyline
• Amitriptyline and chlordiazepoxide
• Amitriptyline and perphenazine

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

N06AA09

CAS registry number (Chemical Abstracts Service)

0000050-48-6

Chemical Formula

C20-H23-N

Molecular Weight

277

Therapeutic Category

Antidepressant, tricyclic

Chemical Name

5-(3-Dimetylaminopropylidene)dibenzo[a,d]-cyclohepta-1,4-diene (WHO)

Foreign Names

• Amitriptylinum (Latin)
• Amitriptylin (German)
• Amitriptyline (French)
• Amitriptilina (Spanish)

Generic Names

• Amitriptilina (OS: DCIT)
• Amitriptyline (OS: DCF, BAN)
• MK 230 (IS)
• N 750 (IS)
• Ro 4-1575 (IS)
• Amitriptyline Hydrochloride (OS: BANM, JAN)
• Amitriptyline (chlorhydrate d') (PH: Ph. Eur. 9)
• Amitriptyline hydrochloride (PH: Ph. Eur. 9)
• Amitriptyline Hydrochloride (PH: BP 2018, JP XVII, Ph. Int. 7, USP 41)
• Amitriptylinhydrochlorid (PH: Ph. Eur. 9)
• Amitriptylini hydrochloridum (PH: Ph. Eur. 9, Ph. Int. 7)

Brand Names

• Abitrip
  Alpic Biotech, India
• Abitrip Forte [+ Chlordiazepoxide]
  Alpic Biotech, India
• Abitrip Plus [+ Chlordiazepoxide]
  Alpic Biotech, India
• Ambival
  Dycine, India
• Amicon
  Mesmer, India
• Amicon Forte [+ Chlordiazepoxide]
  Mesmer, India
• Amiline
  Torrent, Kenya
• Amiplin
  Kobayashi Kako, Taiwan
• Amiptril
  Rospaw, Argentina
• Amitie
  Gautier, Uruguay
• Amitone
  Intas, India
• Amitor
  Torrent, India
• Amitrac
  Minova, India
• Amitrac-CZ [+ Chlordiazepoxide]
  Minova, India
• Amitrip
  East West, India; Laboratory & Allied Equipment, Kenya
• Amitriptilina
  Medrock, Peru
• Amitriptilina Andromaco
  Laboratorios Andromaco, Chile
• Amitriptilina Cevallos
  Cevallos, Argentina
• Amitriptilina Fmndtria
  Farmindustria, Peru
• Amitriptilina Iqfarma
  Iqfarma, Peru
• Amitriptilina L.CH.
  Chile S.A., Paraguay; Laboratorio Chile, Chile
• Amitriptilina La Santé
  La Santé, Costa Rica; La Santé, Panama
• Amitriptilina Luar
  Quim Luar, Argentina
• Amitriptilins-Grindeks
  Grindeks, Latvia
• Amitriptine
  FPI, Egypt
• Amitriptylin Abcur
  Abcur, Denmark
• Amitriptylin Zentiva
  Saneca, Georgia
• Amitriptyline
  Cosmos, Kenya
• Amitriptyline BB
  Brown & Burk, Netherlands
• Amitriptyline-Grindeks
  Grindeks, Lithuania
• Amitriptyline-IKA
  Ikapharm, Kenya
• Amitriptylinum Meda
  SIA Meda Pharma, Lithuania
• Amypres
  Psycorem, India
• Amypres-C [+ Chlordiazepoxide]
  Psycorem, India
• Amytril
  Cristália, Brazil; Pharmacare, Tunisia
• Apo-Amitriptyline
  Apotex, Hong Kong; Apotex, Lithuania; Apotex, Singapore
• Apo-Amitriptyline 10 mg
  Apotex, Lithuania
• Arpidox
  Intra, India
• Axeptyl [+ Chlordiazepoxide]
  Cheminter, Guatemala
• Cuait-D [+ Trifluoperazine]
  Bagó, Colombia
• Diaztric-A [+ Chlordiazepoxide]
  Cubit, India
• Emotrip [+ Chlordiazepoxide]
  IPCA, India
• Kamitrin
  Saga, India
• Klotriptyl Mite [+ Chlordiazepoxide]
  Orion Pharma, Finland
• Laroxyl
  Deva, Turkey
• Latilin
  La Pharmaceuticals, India
• Limbitrol [+ Chlordiazepoxide]
  Hoffmann La Roche, Kuwait
• Limbival Forte [+ Chlordiazepoxide]
  Micro Synapse, India
• Limbritol [+ Chlordiazepoxide]
  Transfarma Medica Indah/Valeant, Indonesia
• Maxitrip
  Invision, India
• Mitryp
  Baroda, India
• Mitryp Forte [+ Chlordiazepoxide]
  Baroda, India
• Morelin [+ Chlordiazepoxide]
  Laboratorio Chile, Chile
• Mutabon Ansiolitico [+ Perphenazine]
  Schering, Italy
• Mutabon Antidepressivo [+ Perphenazine]
  Schering-Plough, Italy
• Mutabon Forte [+ Perphenazine]
  Schering-Plough, Italy
• Mutabon Mite [+ Perphenazine]
  Schering-Plough, Italy
• Odep
  Crescent, India
• Ormal
  Delorbis Pharmaceuticals, Cyprus
• Ristryl [+ Chlordiazepoxide]
  Dycine, India
• Ristryl Forte [+ Chlordiazepoxide]
  Dycine, India
• Saroten Retard
  C G Papaloisou, Cyprus; Lundbeck, Lithuania
• Sarotex 10mg
  Dispert, Uruguay
• Sarotex 25mg
  Dispert, Uruguay
• Tadamit
  Alkem, India
• Teperinep 25 mg
  ExtractumPharma, Hungary
• Teperinep 50 mg
  ExtractumPharma, Hungary
• Trepiline
  Aspen Pharmacare, South Africa
• Triamyl
  PharmaSwiss, Serbia
• Trilin
  Harsen, Indonesia; Triton, India
• Tripox [+ Chlordiazepoxide]
  Triton, India
• Triptiline
  Johnlee, India
• Triptric
  Cubit, India
• Tryptalgin
  Craveri, Argentina
• Tryptanol 25
  Bago, Argentina
• Tryptanol 75
  Bago, Argentina
• Tryptizol
  Algorithm, Lebanon; MSD, Egypt
• Typlin
  Sterkem, India
• Typlin-OD
  Sterkem, India
• Adepril
  Teofarma, Italy
• Adepsique [+ Diazepam, + Perphenazine]
  Psicofarma, Mexico
• ADT
  Generis, Portugal
• Alkym 10mg
  Lasca, Paraguay
• Alkym 25mg
  Lasca, Paraguay
• Alkym 75mg
  Lasca, Paraguay
• Amichlor [+ Chlordiazepoxide]
  Orchid, India
• Amilavil
  Hasan-Dermapharma, Vietnam
• Amilin
  Opsonin, Bangladesh
• Amineurin
  Hexal, Germany
• Amineurin retard
  Hexal, Germany
• Amirol
  Accord Healthcare, Malta; AFT, New Zealand; Remedica, Cyprus; Remedica, Kenya; Remedica, Malta
• Amit
  General Pharma, Bangladesh
• Amitin
  Glitz, Pakistan
• Amitrip
  Mylan, New Zealand
• Amitriptilina
  Recipe, Colombia
• Amitriptilinã Arena
  Arena, Romania
• Amitriptilina Clorhidrato Mintlab
  Mintlab Co., Chile
• Amitriptilina Eurofarma
  Eurofarma, Brazil
• Amitriptilina HCL Teuto
  Teuto Brasileiro, Brazil
• Amitriptilina La Santé
  La Santé, Colombia
• Amitriptilina Lafedar
  Lafedar, Argentina
• Amitriptilina MK
  MK, Colombia
• Amitriptilino 25 mg Sanitas
  Sanitas, Lithuania
• Amitriptylin Abcur
  Abcur, Denmark; Abcur, Iceland; Abcur, Norway; Abcur, Sweden
• Amitriptylin beta
  Betapharm, Germany
• Amitriptylin DAK
  Takeda Pharma, Denmark
• Amitriptylin Grindeks
  Grindeks, Georgia
• Amitriptylin Leciva
  Zentiva, Lithuania
• Amitriptylin Micro Labs
  Micro Labs, Germany
• Amitriptylin Pliva
  Pliva, Lithuania
• Amitriptylin Slovakofarma
  Zentiva, Czech Republic
• Amitriptylin-CT
  AbZ-Pharma, Germany
• Amitriptylin-dura
  Mylan dura, Germany
• Amitriptylin-dura retard
  Mylan dura, Germany
• Amitriptyline
  Actavis UK Ltd, Iceland; Biodeal, Kenya; Clonmel, Kenya; Cosmos, Kenya; Experimental Plant GNCLS, Georgia; Farmalogist, Serbia; GlaxoSmithKline, Bangladesh; Gracure, Kenya; Ozon, Georgia
• Amitriptyline 10mg
  Brown & Burk, United Kingdom
• Amitriptyline 10mg Accord
  Accord Healthcare, United Kingdom
• Amitriptyline 10mg Actavis
  Actavis UK, United Kingdom
• Amitriptyline 10mg Wockhardt
  Wockhardt UK, United Kingdom
• Amitriptyline 25mg
  Brown & Burk, United Kingdom
• Amitriptyline 25mg Accord
  Accord Healthcare, United Kingdom
• Amitriptyline 25mg Actavis
  Actavis UK, United Kingdom
• Amitriptyline 25mg Wockhardt
  Wockhardt UK, United Kingdom
• Amitriptyline 50mg
  Brown & Burk, United Kingdom
• Amitriptyline 50mg Actavis
  Actavis UK, United Kingdom
• Amitriptyline 50mg Wockhardt
  Wockhardt UK, United Kingdom
• Amitriptyline Accord
  Accord Healthcare, Malta
• Amitriptyline Actavis
  Actavis, Hong Kong
• Amitriptyline Alphapharm
  Alphapharm, Australia
• Amitriptyline Central Procurement
  Central Procurement & Supplies Unit, Malta
• Amitriptyline Changzhou Siyao
  Siyao Pharmaceuticals, China
• Amitriptyline Chen Ho
  Chen Ho, Taiwan
• Amitriptyline Grindex
  Grindeks, Latvia
• Amitriptyline HCl Apotex
  Apotex Nederland, Netherlands
• Amitriptyline HCl Aurobindo
  Aurobindo, Netherlands
• Amitriptyline HCl CF
  Centrafarm, Netherlands
• Amitriptyline HCl Mylan
  Mylan, Netherlands
• Amitriptyline HCl Sandoz
  Sandoz, Netherlands
• Amitriptyline HCl Teva
  Teva Nederland, Netherlands
• Amitriptyline hydrochloride
  Sawai Seiyaku, Japan
• Amitriptyline hydrochloride 10mg/5ml Thame
  Thame, United Kingdom
• Amitriptyline Hydrochloride 10mg/5ml Wockhardt
  Wockhardt UK, United Kingdom
• Amitriptyline Hydrochloride 25mg/5ml Rosemont
  Rosemont Pharmaceuticals, United Kingdom
• Amitriptyline hydrochloride 25mg/5ml Thame
  Thame, United Kingdom
• Amitriptyline Hydrochloride 25mg/5ml Wockhardt
  Wockhardt UK, United Kingdom
• Amitriptyline Hydrochloride 50mg/5ml Rosemont
  Rosemont Pharmaceuticals, United Kingdom
• Amitriptyline hydrochloride 50mg/5ml Thame
  Thame, United Kingdom
• Amitriptyline Hydrochloride 50mg/5ml Wockhardt
  Wockhardt UK, United Kingdom
• Amitriptyline Hydrochloride USP
  Medopharm, Georgia
• Amitriptyline Hydrochloride Wockhardt
  Wockhardt, Cyprus; Wockhardt, Malta
• Amitriptyline Jinup
  Jinup, Taiwan
• Amitriptyline MEDA 10mg
  ICN, Bulgaria
• Amitriptyline MEDA 25mg
  ICN, Bulgaria
• Amitriptyline NeoFarma
  NeoFarma, Malta
• Amitriptyline Nikomed
  Takeda, Georgia
• Amitriptyline Nycomed
  Takeda Pharma AS, Estonia
• Amitriptyline PhP
  Pharmaplant Ltd., Netherlands
• Amitriptyline Pro Doc
  Pro Doc, Canada
• Amitriptyline Remedica
  Remedica, Macedonia
• Amitriptyline Sivem
  Sivem Pharmaceuticals, Canada
• Amitriptyline Update
  Update, Taiwan
• Amitriptyline Wockhardt
  Wockhardt, Malta
• Amitriptyline-Grindeks
  AS Grindeks, Estonia
• Amitriptyline-Humanity
  Celogen, Georgia
• Amitriptylin-neuraxpharm
  neuraxpharm Arzneimittel, Germany
• Amitriptylin-neuraxpharm 100mg
  neuraxpharm Arzneimittel, Germany
• Amitriptylin-neuraxpharm 10mg
  neuraxpharm Arzneimittel, Germany
• Amitriptylin-neuraxpharm 25mg
  neuraxpharm Arzneimittel, Germany
• Amitriptylin-neuraxpharm 25mg retard
  neuraxpharm Arzneimittel, Germany
• Amitriptylin-neuraxpharm 50mg retard
  neuraxpharm Arzneimittel, Germany
• Amitriptylin-neuraxpharm 75mg
  neuraxpharm Arzneimittel, Germany
• Amitriptylin-neuraxpharm 75mg retard
  neuraxpharm Arzneimittel, Germany
• Amitriptylin-Sandoz
  Sandoz, Germany
• Amitriptylin-Slovakofarma
  Zentiva, Lithuania; Zentiva, Slovakia
• Amitriptylinum Meda
  Meda Pharma, Latvia
• Amitriptylinum VP
  PharmaSwiss, Poland
• Amitryp
  Raza, Pakistan
• Amitryptyline GPO
  GPO, Thailand
• Amixide [+ Chlordiazepoxide]
  Sun, India
• Amixide-H [+ Chlordiazepoxide]
  Sun, India
• Amizep [+ Chlordiazepoxide]
  La Pharmaceuticals, India
• Amizep H [+ Chlordiazepoxide]
  La Pharmaceuticals, India
• Amotrip
  Pharmedic, Pakistan
• Amyline
  Siza, Pakistan
• Amytril
  Supera RX, Brazil
• Amyzol
  Lek, Slovenia; LEK farmacevtska, Macedonia; Sandoz, Croatia (Hrvatska)
• Anapsique
  Psicofarma, Ecuador; Psicofarma, Mexico
• Antalin [+ Chlordiazepoxide]
  Laboratorio Saval, Chile
• Antalin Forte [+ Chlordiazepoxide]
  Laboratorio Saval, Chile
• Apo-Amitriptyline
  Apotex, Australia; Apotex, Canada
• Arpidox-CP [+ Chlordiazepoxide]
  Intra, India
• Arrow Amitriptyline
  Teva, New Zealand
• Chemmart Amitriptyline
  Apotex, Australia
• Clor. de Amitriptilina (C1) Gen.Germed
  Genéric.Germed, Brazil
• Cloridrato de Amitriptilina EMS
  EMS, Brazil
• Cloridrato de Amitriptilina Eurofarma
  Eurofarma, Brazil
• Cloridrato de Amitriptilina Gen.Germed
  Genéric.Germed, Brazil
• Cloridrato de Amitriptilina Gen.Legrand
  Genéric.Legrand, Brazil
• Cloridrato de Amitriptilina Medley
  Medley, Brazil
• Cloridrato de Amitriptilina Neo Quimica
  Neo Química, Brazil
• Deprelio
  Aldo Union, Spain
• Diapatol [+ Chlordiazepoxide]
  Teofarma, Italy
• Elatrol
  Teva, Israel
• Elatrolet
  Teva, Israel
• Elavil
  AA Pharma, Canada; Gerda, France
• Endep
  Alphapharm, Australia; Alphapharm, Hong Kong
• Entrip
  Arrow Pharmaceuticals, Australia
• Fiorda
  Lafedar, Argentina
• Imidol
  Siza, Pakistan
• Jamp Amitriptyline
  Jamp Pharma, Canada
• Klotriptyl [+ Chlordiazepoxide]
  Orion Pharma, Finland
• Laroxyl
  Teofarma, France; Teofarma, Italy; Teofarma, Morocco
• Libotryp [+ Chlordiazepoxide]
  Wockhardt, India
• Libotryp-DS [+ Chlordiazepoxide]
  Wockhardt, India
• Libotryp-XL [+ Chlordiazepoxide]
  Wockhardt, India
• Limbitrol [+ Chlordiazepoxide]
  Crescent, India; MEDA Pharma, Switzerland; Pharmaco, South Africa; Valeant, Brazil
• Limbitrol-H [+ Chlordiazepoxide]
  Crescent, India
• Limbitryl [+ Chlordiazepoxide]
  Valeant Pharmac. Italy, Italy
• Limbival [+ Chlordiazepoxide]
  Micro Synapse, India
• Mar-Amitriptyline
  Marcan Pharmaceuticals, Canada
• Maxitrip-CZ [+ Chlordiazepoxide]
  Invision, India
• Minitran [+ Perphenazine]
  Adelco, Greece
• Modup
  Swiss Pharm, Taiwan
• Mutabon [+ Perphenazine]
  Schering-Plough, Indonesia
• Neurotol
  Eticos, Paraguay
• Neurotol Forte
  Eticos, Paraguay
• Nobritol [+ Medazepam]
  Kern Pharma, Spain
• Nobritol Forte [+ Medazepam]
  Kern Pharma, Spain
• Perphenazine and Amitriptyline Hydrochloride [+ Perphenazine]
  Mylan, United States
• Pertriptyl [+ Perphenazine]
  Orion Pharma, Finland
• Pinsaun
  Yu Sheng, Taiwan
• PMS-Amitriptyline
  Pharmascience, Canada
• Polytanol
  Central Poly, Thailand
• Qualitriptine
  Quality Pharm, Hong Kong
• Redomex
  Lundbeck, Belgium
• Redomex 10mg
  Lundbeck, Luxembourg
• Redomex 25mg
  Lundbeck, Luxembourg
• Sandoz Amitriptyline
  Sandoz, South Africa
• Saroten
  Lundbeck, Bangladesh; Lundbeck, Denmark; Lundbeck, Sweden; png Gerolymatos, Greece; Lundbeck, Lithuania
• Saroten 10 mg
  Lundbeck Austria, Austria
• Saroten 25 mg
  Lundbeck Austria, Austria
• Saroten 50mg
  Bayer Vital, Germany
• Saroten Retard
  Lundbeck, Bangladesh
• Saroten Retard 25 mg
  Lundbeck, Switzerland; Lundbeck Austria, Austria
• Saroten Retard 50 mg
  Bayer Schweiz, Switzerland; Lundbeck Austria, Austria
• Saroten retard 75mg
  Bayer Vital, Germany
• Sarotena
  Lundbeck, India
• Sarotex
  Lundbeck, Norway
• Sedans [+ Chlordiazepoxide]
  Ganassini, Italy
• Sindepres
  Lafedar, Argentina
• Stelminal
  Coup, Greece
• Syneudon 50mg
  Krewel Meuselbach, Germany
• Terry White Chemists Amitriptyline
  Apotex, Australia
• Teva-Amitriptyline
  Teva Canada, Canada
• Trip
  Medicon, Bangladesh
• Tripgen
  InnoGen, Philippines
• Tripta
  Atlantic Lab, Thailand
• Triptil
  Whelp Paraguay, Paraguay
• Triptizol
  SIT, Italy
• Triptyl
  Orion Pharma, Finland
• Triptyline
  Medifive, Thailand
• Tripyline
  The Central, Taiwan
• Trynol
  Johnson, Taiwan
• Tryptanol
  Merck Sharp & Dohme, Ecuador; Merck Sharp & Dohme, Taiwan; Merck Sharp & Dohme, Venezuela; Nichi-Iko Pharmaceutical, Japan
• Tryptin
  Square, Bangladesh
• Tryptizol
  Algorithm S.A.L., Oman; Merck Sharp & Dohme, Kuwait; Rovi, Spain
• Tryptomer
  Wockhardt, India
• Typlin-C [+ Chlordiazepoxide]
  Sterkem, India
• Typlin-C Plus [+ Chlordiazepoxide]
  Sterkem, India

Glossary

Further information on drug naming conventions: International Nonproprietary Names.