Brompheniramine is an antihistamine. Dextromethorphan is a cough suppressant. Pseudoephedrine is a decongestant.

Anaplex DM is a combination medicine used to treat cough, runny or stuffy nose, sneezing, and watery eyes caused by allergies or the common cold.

Anaplex DM may also be used for purposes not listed in this medication guide.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Follow all directions when giving this medicine to a child. Do not use the medicine to make a child sleepy. Misuse of this medicine may cause death in very young children.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

If you need surgery or medical tests, tell the doctor ahead of time if you have taken this medicine within the past few days.

Store tightly closed at room temperature, away from moisture and heat.

You should not use this medicine if you are allergic to it brompheniramine, dextromethorphan, or pseudoephedrine, or if you have:

• severe high blood pressure; or

• severe coronary artery disease (clogged arteries).

Do not use Anaplex DM if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Tell your doctor if you have ever had:

• asthma or COPD (chronic obstructive pulmonary disease);

• a cough with mucus, or a cough caused by smoking, asthma, or emphysema;

• a blockage in your digestive tract (stomach or intestines);

• a bladder obstruction or other urination problems;

• high blood pressure, heart disease;

• glaucoma;

• diabetes; or

• overactive thyroid.

Tell your doctor if you are pregnant.

Do not breastfeed.

Anaplex DM is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

Do not take more than 6 doses in 24 hours.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling depressed or restless, fast or irregular heartbeats, severe drowsiness, loss of coordination, or seizure.

Ask a doctor or pharmacist before taking other cough or cold medicines that may contain similar ingredients.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Avoid becoming overheated or dehydrated during exercise and in hot weather. This medicine can decrease sweating and you may be more prone to heat stroke.

Drinking alcohol with this medicine can cause side effects.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

• hallucinations;

• a seizure;

• painful or difficult urination;

• a light-headed feeling, like you might pass out;

• fast or pounding heartbeats;

• pale skin, weakness, easy bruising or bleeding, fever, chills, body aches; or

• severe headache, blurred vision, pounding in your neck or ears.

Common side effects of Anaplex DM may include:

• dizziness, drowsiness;

• coughing up thick mucus;

• feeling restless or excited (especially in children); or

• dry mouth, nose, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.