Centruroides scorpion antivenom is used to treat a person who has been stung by a scorpion.

Antivenom (Centruroides scorpion) may also be used for purposes not listed in this medication guide.

If you receive this antivenom during an emergency, make sure any follow-up doctor knows you received antivenom.

You should receive Centruroides scorpion antivenom as soon as possible after you first have symptoms of a scorpion sting (such as slurred speech, increased salivation, vomiting, feeling short of breath, abnormal eye movements, or loss of muscle control).

Centruroides scorpion antivenom is injected into a vein by a healthcare provider.

This antivenom must be given over 10 minutes.

You will be watched for up to 60 minutes to make sure you do not have an allergic reaction.

You may need to additional doses every 30 to 60 minutes.

Your doctor will need to check your progress at a follow-up visit.

Usual Adult Dose for Venomous Scorpion Bite:

Initial dose: 3 vials, IV over 10 minutes

If needed after initial dose: 1 vial, IV over 10 minutes, every 30 to 60 minutes

Comments:
-Start as soon as possible after scorpion sting in those with clinically important signs of envenomation (e.g. loss of muscle control, roving/abnormal eye movements, slurred speech, respiratory distress, excessive salivation, frothing at the mouth, vomiting).
-Monitor patient closely during, and up to 60 minutes after, infusion to see if clinically important envenomation symptoms resolve.

Usual Pediatric Dose for Venomous Scorpion Bite:

Initial dose: 3 vials, IV over 10 minutes

If needed after initial dose: 1 vial, IV over 10 minutes, every 30 to 60 minutes

Comments:
-Start as soon as possible after scorpion sting in those with clinically important signs of envenomation (e.g. loss of muscle control, roving/abnormal eye movements, slurred speech, respiratory distress, excessive salivation, frothing at the mouth, vomiting).
-Monitor patient closely during, and up to 60 minutes after, infusion to see if clinically important envenomation symptoms resolve.

If possible during an emergency, tell your medical caregivers if you are allergic to horses, or if you are pregnant or breastfeeding.

Centruroides scorpion antivenom is made from horse plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.

Make sure any follow-up doctor knows you received this medicine.

In an emergency medical setting, you are not likely to miss a dose.

In a medical setting an overdose would be treated quickly.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a fever, swollen glands, muscle pain, joint pain (which may occur up to 2 weeks after the injection is given).

Common side effects of antivenom may include:

• nausea, vomiting;

• fever;

• rash, itching; or

• muscle pain where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.