Artesunate is used to treat severe malaria in adults and children.

Artesunate may also be used for purposes not listed in this medication guide.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Artesunate is injected into a vein by a healthcare provider.

You may be given an additional malaria medicine during or after treatment with artesunate.

Artesunate injections are usually given every day until you can take malaria medication by mouth.

You will need medical tests for 4 weeks after you finish artesunate treatments.

You should not use artesunate if you are allergic to it.

Tell your doctor if you have ever had kidney problems.

Tell your doctor if you are pregnant. Malaria is more likely to cause serious illness or death in a pregnant woman. Having malaria during pregnancy may also increase the risk of miscarriage, stillbirth, premature delivery, and low birth weight.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of artesunate on the baby.

Ask a doctor if it is safe to breastfeed while using artesunate.

In a medical setting you are not likely to miss a dose.

In a medical setting an overdose would be treated quickly.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Artesunate may cause serious side effects. Call your doctor at once if you have:

• jaundice (yellowing of the skin or eyes);

• pale or yellowed skin, dark colored urine;

• fever, confusion or weakness; or

• kidney problems--swelling, urinating less, feeling tired or short of breath.

Common side effects of artesunate may include:

• kidney problems;

• jaundice; or

• abnormal urine tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Other drugs may affect artesunate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.