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Home > Drugs > Local injectable anesthetics > Articaine and epinephrine
Local injectable anesthetics

Articaine and epinephrine

https://themeditary.com/drug/articaine-and-epinephrine-5974.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Aug 13, 2023  Additional Content by TheMediTary.Com

Generic name: articaine and epinephrine [ ar-ti-kane-and-ep-i-nef-rin ]

Drug class: Local injectable anesthetics

Dosage form: injectable solution (4%-1:100000; 4%-1:200,000)

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Septocaine, Articaine (monograph)

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Articaine and epinephrine?

Articaine and epinephrine are anesthetics (numbing medicines). They work by blocking nerve signals in your body.

Articaine and epinephrine is a combination medicine used to numb your mouth for a dental procedure.

Articaine and epinephrine may also be used for purposes not listed in this medication guide.

Warnings

You should not receive articaine and epinephrine if you have ever had an allergic reaction to any type of numbing medicine.

How should I use Articaine and epinephrine

Articaine and epinephrine is given as an injection that is usually placed into the gum area inside your mouth. You will receive this injection in a dentist's office or oral surgical setting.

Detailed Articaine / epinephrine dosage information
Articaine and epinephrine Dosage information (more detail)

Before Taking

You should not receive articaine and epinephrine if you are allergic to any type of numbing medicine.

To make sure articaine and epinephrine is safe for you, tell your doctor if you have:

  • a heart rhythm disorder;

  • low or high blood pressure;

  • asthma or a sulfite allergy; or

  • a history of seizures.

FDA pregnancy category C. It is not known whether articaine and epinephrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether articaine and epinephrine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

What happens if I miss a dose?

Since articaine and epinephrine is given as needed before a dental procedure, you are not likely to be on a dosing schedule.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme drowsiness, fainting, seizure (convulsions), shallow breathing, or slow heart rate.

What should I avoid while using Articaine and epinephrine?

This medication can cause numbness for an extended period of time. Avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.

Articaine and epinephrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling or puffiness of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • weak or shallow breathing;

  • a slow heart rate;

  • a light-headed feeling, like you might pass out;

  • blurred vision, ringing in your ears; or

  • anxiety, confusion, restless feeling, or tremors.

Call your doctor or dentist at once if you have any swelling, pain, or heavy bleeding after your procedure.

Common side effects of articaine and epinephrine may include:

  • tongue pain or swelling, red or swollen gums;

  • mild swelling in your face;

  • headache; or

  • numbness and tingling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Articaine and epinephrine Side Effects

What other drugs will affect Articaine and epinephrine?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with articaine and epinephrine, especially:

  • an antidepressant--amitriptylline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, trimipramine;

  • antipsychotic medication--chlorpromazine, droperidol, fluphenazine, haloperidol, perphenazine; or

  • an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This list is not complete. Other drugs may interact with articaine and epinephrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

More about Articaine and epinephrine (Articaine and epinephrine [ ar-ti-kane-and-ep-i-nef-rin ])

Dosage information
Articaine and epinephrine Side Effects
During pregnancy
Drug images
Side effects
Drug class: Local injectable anesthetics

Related treatment guides

Anesthesia
Local Anesthesia
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions
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