Anti-inhibitor coagulant complex is used in people who have hemophilia and have developed antibodies to clotting factor medications.

Hemophilia, an inherited blood-clotting disorder, is often treated with medicines containing clotting factors that help control bleeding. When the body develops antibodies or "inhibitors" to the clotting factor, this treatment becomes less effective in preventing bleeding episodes. Anti-inhibitor coagulant complex works by bypassing the effects of these inhibitors to improve blood clotting and decrease the risk of bleeding.

Anti-inhibitor coagulant complex is used to treat or prevent bleeding episodes in people with hemophilia A or B who have developed inhibitors. This medicine is also used to control bleeding related to surgery in people with hemophilia and inhibitors. Anti-inhibitor coagulant complex is not for treating bleeding episodes in people who do not have inhibitors.

Anti-inhibitor coagulant complex may also be used for purposes not listed in this medication guide.

You should not use anti-inhibitor coagulant complex if:

• you have had a severe allergic reaction to this medicine or other antihemophilic factors;
• you have a blood condition called disseminated intravascular coagulation;
• you have a current blood clot anywhere in your body; or
• you have recently had a stroke or heart attack.

To make sure anti-inhibitor coagulant complex is safe for you, tell your doctor if you have:

• coronary artery disease;
• a history of heart attack, stroke, or blood clot;
• a recent major injury; or
• a serious infection called sepsis.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether anti-inhibitor coagulant complex passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Anti-inhibitor coagulant complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

Use Autoplex T (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor or seek emergency medical help right away if you have:

• bruising, swelling, or pain around a joint;
• heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
• low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
• signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
• signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood or;
• signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs.

Common side effects may include:

• anemia;
• nausea, vomiting, diarrhea;
• bruising;
• altered sense of taste; or
• a positive hepatitis B antibody test.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.