Almotriptan is a headache medicine that narrows blood vessels around the brain. Almotriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Almotriptan is used to treat migraine headaches in adults and in adolescents who are at least 12 years old. Almotriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Almotriptan should not be used to treat a common tension headache, a headache that causes loss of movement on one side of your body, or any headache that seems to be different from your usual migraine headaches. Use this medicine only if your condition has been confirmed by a doctor as migraine headaches.

Almotriptan may also be used for purposes not listed in this medication guide.

You should not take almotriptan if you are allergic to it, or if you have:

• severe or uncontrolled high blood pressure;
• past or present heart problems;
• history of coronary artery disease, angina, (chest pain), heart attack, or stroke, including "mini-stroke";
• a blood vessel disorder or circulation problems that cause a lack of blood supply within the body; or
• a headache that seems different from your usual migraine headaches.

To make sure almotriptan is safe for you, tell your doctor if you have ever had:

• a sulfa drug allergy;
• liver or kidney disease;
• kidney disease;
• high blood pressure, a heart rhythm disorder; or
• risk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of heart disease, or being older than 40 and a man).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether almotriptan passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medicine to anyone under 12 years old.

Use Axert (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using almotriptan and get emergency medical help if you have heart attack symptoms: chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating, and feeling light-headed.

Stop using almotriptan and call your doctor at once if you have:

• numbness or tingling and a pale or blue-colored appearance in your fingers or toes;
• blood circulation problems--weakness or heavy feeling in your legs, burning pain in your feet, leg cramps, hip pain, numbness or tingling in your legs;
• high levels of serotonin in the body--agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting; or
• stomach or intestinal problems--severe stomach pain (especially after eating), fever, nausea, vomiting, diarrhea, constipation, bloody or tarry stools.

Common side effects may include:

• dry mouth;
• nausea, vomiting;
• numbness, tingling, or burning sensation;
• dizziness, drowsiness; or
• mild headache (not a migraine).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Do not take almotriptan within 24 hours before or 24 hours after using another migraine headache medicine, including:

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Almotriptan may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.