Nizatidine is a histamine-2 blocker that works by decreasing the amount of acid produced by the stomach.

Nizatidine is used to treat ulcers in the stomach and intestines. Nizatidine also treats heartburn and erosive esophagitis caused by gastroesophageal reflux disease (GERD), a condition in which acid backs up from the stomach into the esophagus.

Nizatidine may also be used for purposes not listed in this medication guide.

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:

You should not use this medicine if you are allergic to nizatidine or similar stomach medicines such as ranitidine (Zantac), cimetidine (Tagamet), or famotidine (Pepcid).

It is not known whether nizatidine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Nizatidine can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking this medication.

Do not give this medication to a child younger than 12 years old without the advice of a doctor.

• pain when swallowing food;
• bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
• heartburn that has lasted for longer than 3 months;
• heartburn that causes you to wheeze or feel like you might pass out;
• unusual weight loss;
• stomach pain, nausea, or vomiting;
• frequent chest pain;
• kidney disease; or
• liver disease.

Use Axid Pulvules (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have hives; difficulty breathing; swelling of your face, lips, tongue, or throat. signs of an allergic reaction:

Stop using nizatidine and call your doctor at once if you have:

• worsening heartburn;
• chest pain;
• pale skin, feeling light-headed or short of breath; or
• jaundice (yellowing of the skin or eyes).

• headache, dizziness;
• diarrhea; or
• runny or stuffy nose.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

To help manage your heartburn symptoms, avoid certain things that can make heartburn worse, such as:

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