In the US, Bevacizumab (bevacizumab systemic) is a member of the drug class VEGF/VEGFR inhibitors and is used to treat Breast Cancer, Breast Cancer - Metastatic, Cervical Cancer, Colorectal Cancer, Fallopian Tube Cancer, Glioblastoma Multiforme, Hepatocellular Carcinoma, Macular Degeneration, Malignant Glioma, Neurofibromatosis, Non-Small Cell Lung Cancer, Ovarian Cancer, Pancreatic Cancer, Peritoneal Cancer, Renal Cell Carcinoma and Solid Tumors.

US matches:

• Bevacizumab
• Bevacizumab-adcd
• Bevacizumab-awwb
• Bevacizumab-bvzr
• Bevacizumab-maly
• Bevacizumab Injection

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XC07

CAS registry number (Chemical Abstracts Service)

0216974-75-3

Chemical Formula

C6638-H10160-N1720-O2108-S44

Therapeutic Categories

Antineoplastic agent

Monoclonal antibody

Angiogenesis inhibitor

Vascular endothelial growth factor (VEGF) antagonist

Chemical Name

Immunoglobulin G1 (human-mouse monoclonal rhuMAb-VEGF gamma-chain anti-human vascular endothelial growth factor), disulfide with human-mouse monoclonal rhuMab-VEGF light chain, dimer (WHO )

Foreign Names

• Bevacizumabum (Latin)
• Bevacizumab (German)
• Bévacizumab (French)
• Bevacizumab (Spanish)

Generic Names

• Bevacizumab (OS: USAN)
• Bevacizumab (Genetical Recombination) (OS: JAN)
• anti-VEGF Mab (IS)
• Anti-VEGF monoclonal antibody (IS)
• rhuMAb-VEGF (IS)
• UNII-2S9ZZM9Q9V (IS)
• VEGF light chain, dimer (WHO) (IS)

Brand Names

• Altuzan Roche 100mg/4ml
  Roche, Turkey
• Altuzan Roche 400mg/16ml
  Roche, Turkey
• Avastin
  Chugai Pharmaceutical, Japan; F. Hoffmann-La Roche, Macedonia; Genentech, United States; Hoffmann-La Roche, Canada; Hoffmann-La Roche Ltd, Latvia; Productos Roche, Chile; Roche, Armenia; Roche, Argentina; Roche, Bosnia & Herzegowina; Roche, Belgium; Roche, Brazil; Roche, Colombia; Roche, Cyprus; Roche, Czech Republic; Roche, Denmark; Roche, Ecuador; Roche, Estonia; Roche, Egypt; Roche, Spain; Roche, Finland; Roche, Georgia; Roche, Greece; Roche, Croatia (Hrvatska); Roche, Ireland; Roche, Israel; Roche, Italy; Roche, Lebanon; Roche, Lithuania; Roche, Moldova; Roche, Myanmar; Roche, Mexico; Roche, Norway; Roche, New Zealand; Roche, Philippines; Roche, Poland; Roche, Portugal; Roche, Paraguay; Roche, Romania; Roche, Russian Federation; Roche, Sweden; Roche, Thailand; Roche, Taiwan; Roche, Vietnam; Roche, South Africa; Roche D.O.O., Serbia; Roche Farma, Peru; Roche Pharmaceutical, China; Roche Products, Australia; Roche Registration, Netherlands; Roche Registration Limited, Iceland; Roche Registration, Slovenia; Roche Uruguay, Uruguay
• Avastin 100mg/4ml
  Roche, Oman; Roche Pharma Schweiz, Switzerland
• Avastin 25 mg/ml
  Abacus, Austria; Haemato Pharm, Austria; Inopha, Austria; Orifarm, Austria; Roche, Germany; Roche, France; Roche, Hungary; Roche Products, United Kingdom; Roche Registration, Austria
• Avastin 400mg/16ml
  Roche, Oman; Roche Pharma Schweiz, Switzerland
• Avastin Roche
  Roche, Hong Kong
• Avastin-25
  Roche, Luxembourg
• Bevax
  Elea, Argentina
• Mvasi
  Amgen, United States; Amgen Europe, Netherlands

Glossary

Further information on drug naming conventions: International Nonproprietary Names.