Carmustine is used to treat brain tumors, Hodgkin's disease, multiple myeloma, and non-Hodgkin's lymphoma.

Carmustine is sometimes given with other cancer medicines, with radiation or after brain surgery.

Carmustine may also be used for purposes not listed in this medication guide.

You should not be treated with carmustine if you are allergic to it.

Tell your doctor if you have ever had:

• lung disease or breathing problems;
• bone marrow suppression; or
• kidney disease.

Receiving carmustine injection may increase your risk of developing other cancers, such as leukemia. Ask your doctor about this risk.

Carmustine may harm an unborn baby if the mother or the father is using this medicine.

• If you are a woman, do not use carmustine if you are pregnant. Use effective birth control to prevent pregnancy while receiving carmustine. Keep using birth control for at least 6 months after your last injection or after implant placement.
• If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last injection or after implant placement.
• Tell your doctor right away if a pregnancy occurs while either the mother or the father is using carmustine.

This medicine may affect fertility (ability to have children) in men. However, it is important to use birth control to prevent pregnancy because carmustine can harm an unborn baby.

Do not breastfeed while receiving carmustine injection, or for at least 7 days after carmustine implant placement.

Use Bicnu (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

You may have an infusion reaction during the injection or within 2 hours afterward. This may include skin redness, eye redness and severe warmth or tingling under your skin.

Some side effects may not occur many weeks or even years after you receive carmustine.

Call your doctor at once if you have:

• easy bruising, unusual bleeding;
• a seizure;
• unexplained weight loss;
• little or no urination; or
• pain, burning, swelling, or skin changes where the injection was given;
• slow healing of your incision after carmustine implant placement;
• lung problems--a dry cough or hack, shortness of breath (especially with exercise), rapid but shallow breathing, tiredness, body aches, clubbing (widening and rounding) of your fingertips or toes;
• increased pressure inside your skull--sudden vision problems, severe headache, vomiting, dizziness; or
• signs of meningitis--fever, neck stiffness, increased sensitivity to light, nausea, vomiting, confusion, drowsiness.

Common side effects may include:

• bleeding, bruising;
• tiredness;
• nausea, vomiting; or
• breathing problems.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.