Bimatoprost ophthalmic (for the eyes) lowers pressure in the eye by increasing the amount of fluid that drains from the eye.

Bimatoprost ophthalmic implant (Durysta) is used to treat adults with open-angle glaucoma and other causes of high pressure inside the eye.

Bimatoprost ophthalmic implant may also be used for purposes not listed in this medication guide.

You should not be treated with Durysta if you are allergic to bimatoprost, or if you have:

• an infection in or around your eye;
• problems with your cornea (the surface of your eye);
• a history of corneal transplant; or
• if the sack around the lens of your eye (posterior lens capsule) is missing or torn.

Tell your doctor if you have ever had:

• eye problems in the space where your cornea meets your iris (the colored part of your eye);
• cataract surgery; or
• inflammation inside your eye.

Durysta may cause a gradual change in the color of brown eyes, usually an increase in pigment. This change occurs slowly and may be permanent even after your treatment ends.

Use Bimatoprost Ophthalmic Implant (Intraocular) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• worsening eye pain or redness;
• vision changes;
• increased sensitivity to light; or
• signs of eye infection--puffy eyelids, eye redness, severe discomfort, crusting or drainage, vision loss.

Common side effects may include:

• eye redness or a blood spot on the white of your eye;
• eye pain;
• feeling like something is in your eye;
• eye dryness or irritation;
• blurred vision, inflammation of the iris;
• headache;
• increased pressure inside the eye; or
• a loss of cells on the inner layer of your cornea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.