Brexafemme is a prescription medicine used to treat vaginal yeast infection, and to reduce the number of recurrent vaginal yeast infections in adults and adolescent females who have started their menstruation.

It is not known if this medicine is safe and effective in pre-adolescent females who have not started their menstruation.

Treatment with Brexafemme during pregnancy can cause harm to your unborn baby. Women who can become pregnant may be asked by their healthcare provider to take a pregnancy test before each treatment. Women who can become pregnant should use effective birth control throughout the duration of treatment, and for 4 days after the last dose. Talk to your healthcare provider about birth control methods that may be right for you. 

Who should not take Brexafemme?

You should not take Brexafemme if you:

• Are pregnant or plan to become pregnant. Brexafemme may harm your unborn baby. Tell your healthcare provider if you are pregnant, think you might be pregnant, or plan to become pregnant.
• Are allergic to ibrexafungerp.

Before you take Brexafemme

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

• Are pregnant or could become pregnant. Women who can become pregnant may be asked by their healthcare provider to take a pregnancy test before starting treatment. Women who can become pregnant should use effective birth control while taking Brexafemme and for 4 days after the last dose. Talk to your healthcare provider about birth control methods that may be right for you.
• Are breastfeeding or plan to breastfeed. It is not known if Brexafemme passes into your breast milk. You and your healthcare provider should decide if you will take Brexafemme or breast feed.
• Brexafemme may affect the way other medicines work, and other medicines may affect how Brexafemme works.
• Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

• Take Brexafemme exactly as your healthcare provider tells you to take it.
• Take the tablets by mouth with or without food.

You should not take Brexafemme if you:

• Are pregnant or plan to become pregnant. Brexafemme may harm your unborn baby. Tell your healthcare provider if you are pregnant, think you might be pregnant, or plan to become pregnant.
• Are allergic to ibrexafungerp.

Before you take Brexafemme

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

• Are pregnant or could become pregnant. Women who can become pregnant may be asked by their healthcare provider to take a pregnancy test before starting treatment. Women who can become pregnant should use effective birth control while taking Brexafemme and for 4 days after the last dose. Talk to your healthcare provider about birth control methods that may be right for you.
• Are breastfeeding or plan to breastfeed. It is not known if Brexafemme passes into your breast milk. You and your healthcare provider should decide if you will take Brexafemme or breast feed.
• Brexafemme may affect the way other medicines work, and other medicines may affect how Brexafemme works.
• Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects include: loose stools, nausea, stomach pain, dizziness, and vomiting.

These are not all the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA1088.

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Other drugs may interact with ibrexafungerp, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.