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Home > Drugs > Bronchodilator combinations > Budesonide, formoterol, and glycopyrrolate
Bronchodilator combinations

Budesonide, formoterol, and glycopyrrolate

https://themeditary.com/drug/budesonide-formoterol-and-glycopyrrolate-7799.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Aug 16, 2023  Additional Content by TheMediTary.Com

Generic name: budesonide, formoterol, and glycopyrrolate [ bue-des-oh-nide, for-moe-te-rol, and-glye-koe-pir-oh-late ]

Drug class: Bronchodilator combinations

Dosage form: inhalation aerosol (160 mcg-4.8 mcg-9 mcg/inh)

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Breztri aerosphere

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Budesonide, formoterol, and glycopyrrolate?

Budesonide is a steroid. Formoterol is a long-acting bronchodilator. Glycopyrrolate is an anticholinergic.

Budesonide, formoterol, and glycopyrrolate is a combination medicine used in adults to help control the symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

budesonide, formoterol, and glycopyrrolate is not for use in treating asthma or a bronchospasm attack.

Budesonide, formoterol, and glycopyrrolate may also be used for purposes not listed in this medication guide.

Warnings

Budesonide, formoterol, and glycopyrrolate is not a rescue medicine for bronchospasm attacks. Use only fast-acting inhalation medicine for an attack. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well.

How should I take Budesonide, formoterol, and glycopyrrolate

Follow all directions on your prescription label and read all medication guides. Use the medicine exactly as directed. Using too much of this medicine can cause life-threatening side effects.

Budesonide, formoterol, and glycopyrrolate is not a rescue medicine for bronchospasm attacks. Use only fast-acting inhalation medicine for an attack. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Rinse your mouth with water after each use of your inhaler.

Your medication needs may change if you have surgery, are ill, are under stress, or have worsening COPD symptoms. Do not change your medication dose or stop using this medicine without your doctor's advice.

Store at room temperature away from sunlight, open flame, or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.

Do not open the foil pouch until you are ready to use the medicine.

Throw the canister away when the inhalations counter shows a 0, or 3 months after you first removed the 120-inhalation canister from its foil pouch (3 weeks after if you are using the 28-inhalation canister), whichever comes first.

Dosing information

Usual Adult Dose for Chronic Obstructive Pulmonary Disease -- Maintenance:

2 oral inhalations twice a day (morning and evening)
Maximum dose: 2 inhalations twice a day

Comments:
-Limitations of Use: This drug is not indicated for the relief of acute bronchospasm or for the treatment of asthma.
-Each inhalation contains budesonide 160 mcg, formoterol fumarate 4.8 mcg, and glycopyrrolate 9 mcg.

Use: For the maintenance treatment of patients with COPD

Detailed Budesonide / formoterol / glycopyrrolate dosage information
Budesonide, formoterol, and glycopyrrolate Dosage information (more detail)

Before Taking

You should not use this medicine if you are allergic to budesonide, formoterol, or glycopyrrolate (this includes Pulmicort, Rhinocort, Perforomist, Bevespi, Dulera, and others).

Budesonide can weaken your immune system. Tell your doctor about any illness or infection you've had within the past several weeks.

Tell your doctor if you have ever had:

  • heart disease, high blood pressure;

  • a seizure;

  • a weak immune system;

  • liver or kidney disease;

  • osteoporosis;

  • glaucoma, cataracts, or other vision problems;

  • enlarged prostate, urination problems;

  • diabetes;

  • tuberculosis;

  • a weak immune system;

  • a thyroid disorder; or

  • any type of bacterial, fungal, or viral infection.

Tell your doctor if you are pregnant or breastfeeding.

This medicine is not approved for use by anyone younger than 18 years old.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include chest pain, fast heartbeats, and feeling shaky or short of breath.

What should I avoid while using Budesonide, formoterol, and glycopyrrolate?

If this medication gets in your eyes, rinse with water and call your doctor if you have severe eye redness.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using a steroid such as budesonide.

Ask your doctor before using a second inhaled bronchodilator that contains formoterol or a similar medicine (such as arformoterol, formoterol, indacaterol, olodaterol, salmeterol, or vilanterol).

Budesonide, formoterol, and glycopyrrolate side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Budesonide, formoterol, and glycopyrrolate may cause serious side effects. Call your doctor at once if you have:

  • worsened breathing problems;

  • wheezing, choking, or other breathing problems after using this medication;

  • tremors, nervousness, chest pain, fast or pounding heartbeats;

  • sores or white patches in your mouth and throat, pain when swallowing;

  • flu symptoms, body aches, unusual tiredness;

  • painful or burning when you urinate, little or no urination;

  • blurred vision, tunnel vision, eye pain or redness, or seeing halos around lights;

  • low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;

  • signs of a lung infection--fever, chills, cough with mucus, chest pain, feeling short of breath; or

  • signs of a hormonal disorder--tiredness or weakness, feeling light-headed, nausea, vomiting.

Common side effects of budesonide, formoterol, and glycopyrrolate may include:

  • throat pain or irritation;

  • white patches in your mouth or throat;

  • headache, joint pain, muscle spasms;

  • pounding heartbeats, feeling anxious;

  • high blood sugar levels;

  • painful or difficult urination;

  • nausea, diarrhea;

  • cough, hoarse voice;

  • flu symptoms; or

  • cold symptoms such as stuffy or runny nose, sneezing, sinus pain, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Budesonide, formoterol, and glycopyrrolate Side Effects

What other drugs will affect Budesonide, formoterol, and glycopyrrolate?

Tell your doctor about all your current medicines. Do not use any of the following medicines without first asking your doctor:

  • atropine;

  • antiviral or antifungal medication;

  • medicine to treat depression, anxiety, mood disorders, or mental illness;

  • cold or allergy medicine (Benadryl and others);

  • medicine to treat Parkinson's disease;

  • medicine to treat stomach problems, motion sickness, or irritable bowel syndrome;

  • medicine to treat overactive bladder;

  • bronchodilator asthma medication (such as aclidinium, ipratropium, tiotropium, or umeclidinium).

This list is not complete and many other drugs may affect budesonide, formoterol, and glycopyrrolate. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

More about Budesonide, formoterol, and glycopyrrolate (Budesonide, formoterol, and glycopyrrolate [ bue-des-oh-nide, for-moe-te-rol, and-glye-koe-pir-oh-late ])

Dosage information
Budesonide, formoterol, and glycopyrrolate Side Effects
During pregnancy
Drug images
Side effects
Drug class: Bronchodilator combinations

Related treatment guides

COPD
COPD, Maintenance
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