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Home > Drugs > Quinolones and fluoroquinolones > Ciprofloxacin
Quinolones and fluoroquinolones

Ciprofloxacin

https://themeditary.com/drug/ciprofloxacin-150.html
Medically Reviewed by Kaci Durbin, MD TheMediTary.Com | Reviewed: Jul 10, 2023  Additional Content by TheMediTary.Com

Generic name: ciprofloxacin (oral) [ sip-roe-flox-a-sin ]

Drug class: Quinolones and fluoroquinolones

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Cipro, Cipro i.v. (injection), Proquin xr, Ciprofloxacin (injection)

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ
  • Ciprofloxacin (Ciprofloxacin (oral) [ sip-roe-flox-a-sin ])-RX711-750 mg-White-Capsule-shape Ciprofloxacin 750 mg (RX711)
  • Ciprofloxacin (Ciprofloxacin (oral) [ sip-roe-flox-a-sin ])-0863 93-250 mg-White-Round Ciprofloxacin 250 mg (0863 93)
  • Ciprofloxacin (Ciprofloxacin (oral) [ sip-roe-flox-a-sin ])-93 0864-500 mg-White-Oval Ciprofloxacin 500 mg (93 0864)
  • Ciprofloxacin (Ciprofloxacin (oral) [ sip-roe-flox-a-sin ])-93 0865-750 mg-White-Oval Ciprofloxacin 750 mg (93 0865)
  • View all images

What is Ciprofloxacin?

Ciprofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic, it is used to treat different types of bacterial infections. It is also used to treat people who have been exposed to anthrax or certain types of plague. Ciprofloxacin extended-release is only approved for use in adults.

Fluoroquinolone antibiotics can cause serious or disabling side effects that may not be reversible.

Ciprofloxacin should be used only for infections that cannot be treated with a safer antibiotic.

Warnings

Ciprofloxacin can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar.

Stop using ciprofloxacin and call your doctor at once if you have: headache, hunger, irritability, numbness, tingling, burning pain, confusion, agitation, paranoia, problems with memory or concentration, thoughts of suicide, or sudden pain or movement problems in any of your joints.

In rare cases, ciprofloxacin may cause damage to your aorta, which could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.

You may not be able to use this medicine if you have a muscle disorder. Tell your doctor if you have a history of myasthenia gravis.

How should I take Ciprofloxacin

Ciprofloxacin comes as a tablet, a suspension (liquid), and an extended-release tablet to take by mouth with or without food. The tablets and suspension are usually taken twice a day, and the extended-release tablets are usually taken once a day. When used to treat gonorrhea, the tablets and suspension may be given as a single dose. Take ciprofloxacin at around the same time(s) every day. The length of your treatment depends on the type of infection you have. Your doctor will tell you how long to take ciprofloxacin. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ciprofloxacin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

One type of ciprofloxacin cannot be substituted for another. Be sure that you receive only the type of ciprofloxacin that was prescribed by your doctor. Ask your pharmacist if you have any questions about the type of ciprofloxacin you were given.

Do not take ciprofloxacin with dairy products or calcium-fortified juices alone. However, you may take ciprofloxacin with a meal that includes these foods or drinks.

Swallow the tablets whole; do not crush, or chew them. If you doctor tells you to to split the 250-mg or 500-mg tablet, it may be broken in half along the scored line. Swallow the extended-release tablets whole; do not split, crush, or chew them. If you cannot swallow tablets or extended-release tablets whole, tell your doctor.

If you are taking the suspension, shake the bottle very well for 15 seconds before each use to mix the medication evenly. Swallow the correct dose without chewing the granules in the suspension. Close the bottle completely after each use. Do not give the suspension to a patient through a feeding tube.

You should begin feeling better during the first few days of your treatment with ciprofloxacin. If your symptoms do not improve or if they get worse, call your doctor. If you are being treated for a urinary tract infection, call your doctor if you develop fever or back pain during or after your treatment. These symptoms may be signs that your infection is worsening.

Take ciprofloxacin until you finish the prescription, even if you feel better. Do not stop taking ciprofloxacin without talking to your doctor unless you experience certain serious side effects listed in the IMPORTANT WARNING and SIDE EFFECTS sections If you stop taking ciprofloxacin too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Dosing information

Take ciprofloxacin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Take ciprofloxacin at the same time each day, with or without food.

Shake the oral suspension (liquid) for 15 seconds before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Do not give ciprofloxacin oral suspension through a feeding tube.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

Drink plenty of liquids while you are taking this medicine.

Use ciprofloxacin for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Ciprofloxacin will not treat a viral infection such as the flu or a common cold.

Do not share this medicine with another person.

Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze. Throw away any unused liquid after 14 days.

Detailed Ciprofloxacin dosage information
Ciprofloxacin Dosage information (more detail)

Before Taking

You should not use ciprofloxacin if you are allergic to it, or if:

  • you also take tizanidine; or

  • you are allergic to other fluoroquinolones (levofloxacin, moxifloxacin, norfloxacin, ofloxacin).

Ciprofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or several months after you stop taking ciprofloxacin. Tendon problems may be more likely in children and older adults, or people who use steroid medicine or have had an organ transplant.

To make sure ciprofloxacin is safe for you, tell your doctor if you have ever had:

  • arthritis or problems with your tendons, bones or joints (especially in children);

  • diabetes, low blood sugar;

  • nerve problems;

  • an aneurysm or blood circulation problems;

  • heart problems, or a heart attack;

  • muscle weakness, myasthenia gravis;

  • liver or kidney disease;

  • a seizure, head injury, or brain tumor;

  • trouble swallowing pills;

  • long QT syndrome (in you or a family member); or

  • low levels of potassium in your blood (hypokalemia).

Do not give this medicine to a child without medical advice.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

You should not breastfeed while taking ciprofloxacin and for 2 days after your last dose. Ask your doctor about breastfeeding if you take this medicine for anthrax exposure.

Ciprofloxacin pregnancy and breastfeeding warnings (more detail)

What happens if I miss a dose?

If you take regular tablets or oral suspension: Take the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 6 hours.

If you take extended-release tablets: Take the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 8 hours.

Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets and extended-release tablets at room temperature and away from excess heat and moisture (not in the bathroom). Store the suspension in the refrigerator or at room temperature, closed tightly, for up to 14 days. Do not freeze ciprofloxacin suspension. Discard any suspension that is left over after 14 days.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What special dietary instructions should I follow?

Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Ciprofloxacin may increase nervousness, sleeplessness, heart pounding, and anxiety caused by caffeine.

Make sure you drink plenty of water or other fluids every day while you are taking ciprofloxacin.

What should I avoid while using Ciprofloxacin?

Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink these products with your meals, but do not use them alone when taking this medicine.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Ciprofloxacin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Tell your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.

Avoid driving or hazardous activity until you know how ciprofloxacin will affect you. Your reactions could be impaired.

Ciprofloxacin side effects

Get emergency medical help if you have signs of an allergic reaction to ciprofloxacin (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Ciprofloxacin can cause serious side effects, including tendon problems, damage to your nerves (which may be permanent), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma).

Stop taking this medicine and call your doctor at once if you have:

  • low blood sugar - headache, hunger, irritability, dizziness, nausea, fast heart rate, or feeling shaky;

  • nerve damage symptoms - numbness, tingling, burning pain in your hands, arms, legs, or feet:

  • serious mood or behavior changes - nervousness, confusion, agitation, paranoia, hallucinations, memory problems, trouble concentrating, thoughts of suicide; or

  • signs of tendon rupture - sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions).

In rare cases, ciprofloxacin may cause damage to your aorta, the main blood artery of the body. This could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.

Also, stop using this medicine and call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody;

  • fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);

  • any skin rash, no matter how mild;

  • muscle weakness, breathing problems;

  • little or no urination;

  • jaundice (yellowing of the skin or eyes); or

  • increased pressure inside the skull - severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.

Common ciprofloxacin side effects may include:

  • nausea, vomiting, diarrhea, stomach pain;

  • headache; or

  • abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Ciprofloxacin Side Effects

What other drugs will affect Ciprofloxacin?

Some medicines can make ciprofloxacin much less effective when taken at the same time. If you take any of the following medicines, take your ciprofloxacin dose 2 hours before or 6 hours after you take the other medicine.

  • the ulcer medicine sucralfate, or antacids that contain calcium, magnesium, or aluminum (such as Maalox, Milk of Magnesia, Mylanta, Pepcid Complete, Rolaids, Tums, and others);

  • didanosine (Videx) powder or chewable tablets;

  • vitamin or mineral supplements that contain calcium, iron, magnesium, or zinc.

Tell your doctor about all your other medicines, especially:

  • clozapine, cyclosporine, methotrexate, phenytoin, probenecid, ropinirole, sildenafil, or theophylline;

  • a blood thinner (warfarin, Coumadin, Jantoven);

  • heart medication or a diuretic or "water pill";

  • oral diabetes medicine;

  • products that contain caffeine;

  • medicine to treat depression or mental illness;

  • steroid medicine (such as prednisone); o

  • NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;

This list is not complete. Other drugs may interact with ciprofloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to ciprofloxacin. If you have diabetes, your doctor may ask you to check your blood sugar more often while taking ciprofloxacin.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish taking ciprofloxacin, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

What to Expect

You should start to feel better within a few days of taking ciprofloxacin, but this will depend on the type of infection you have.

Because of the risks for serious side effects, doctors usually don’t prescribe ciprofloxacin for longer than three months at a time.

Additional Dosage Information

Your dose of ciprofloxacin will depend on your medical condition, overall health, age, and other factors.

Be sure to take all the medicine your doctor prescribes, even if you feel better. Stopping ciprofloxacin too soon could cause the bacteria to become resistant to antibiotics.

Secondary Uses

Ciprofloxacin may be used to treat or prevent a variety of secondary health conditions, including:

  • Cat scratch disease (an infection that could develop as the result of a cat scratch or bite)
  • Legionnaires’ disease (a type of lung infection)
  • Chancroid (genital sores caused by bacteria)
  • Granuloma inguinale (a sexually transmitted disease)
  • Infections of the outer ear that spread
  • Tuberculosis (TB)
  • Crohn’s disease
  • Traveler’s diarrhea
  • Meningitis
  • Infections in people with few white blood cells
  • Endocarditis (an infection of the heart valves)
  • Infection due to surgery

Ciprofloxacin may also be used for conditions not listed in this guide.

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More about Ciprofloxacin (Ciprofloxacin (oral) [ sip-roe-flox-a-sin ])

Dosage information
Ciprofloxacin Side Effects
Patient tips
During pregnancy
Drug images
Side effects
Drug class: Quinolones and fluoroquinolones

Patient resources

Advanced Reading: Ciprofloxacin (Intravenous)
Advanced Reading: Ciprofloxacin (Oral)
Ciprofloxacin Extended-Release Tablets
Ciprofloxacin Tablets
Ciprofloxacin Oral Suspension

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