Clotrimazole is an antifungal medication that fights infections caused by fungus.

Clotrimazole-3 (for use in the vagina) is used to treat vaginal candida (yeast) infections.

Clotrimazole-3 may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Wash your hands before and after using this medication.

Insert the tablet, suppository, or cream into the vagina using the applicator as directed.

Use this medicine for the full prescribed length of time, even during your menstrual period. Your symptoms may improve before the infection is completely cleared. If the infection does not clear up, or if it appears to get worse, see your doctor.

Call your doctor if your symptoms do not improve after 3 days of treatment, or if they last longer than a week. Tell your doctor right away if you have a skin rash or hives, stomach pain, fever, chills, nausea, vomiting, or foul-smelling vaginal discharge.

You can use a sanitary napkin to prevent the medication from staining your clothing but do not use a tampon.

Store at room temperature away from moisture and heat.

You should not use Clotrimazole-3 if you are allergic to it.

If this is the first time you have ever had symptoms of a vaginal yeast infection, ask your doctor before using Clotrimazole-3.

Tell your doctor if you have had more than 3 vaginal infections within 6 months. Frequent vaginal yeast infections that do not clear up with treatment may be a sign of a more serious condition.

Ask a doctor or pharmacist if it is safe for you to use Clotrimazole-3 if you have other medical conditions, especially:

• fever, chills, pain in your back or shoulder;

• stomach pain, vomiting;

• foul-smelling vaginal discharge;

• diabetes; or

• HIV or AIDS.

FDA pregnancy category B. Clotrimazole-3 is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Do not use Clotrimazole-3 without medical advice if you are breast-feeding a baby.

Do not give this medicine to a child younger than 12 years old without medical advice.

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Do not have sexual intercourse. Clotrimazole-3 will not prevent the infection from spreading to your partner. Clotrimazole topical can also cause damage to a condom or a diaphragm. These forms of birth control may be less effective if you use them during treatment.

Avoid getting this medicine in your eyes, nose, or mouth.

Avoid wearing tight-fitting, synthetic clothing that doesn't allow air circulation. Wear clothing made of loose cotton and other natural fibers until the infection is healed.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have new or worsening vaginal symptoms.

Common side effects of Clotrimazole-3 may include:

• slight increase in vaginal discomfort (burning, itching, irritation).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.