By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Miscellaneous antibiotics > Cubicin
Miscellaneous antibiotics

Cubicin

https://themeditary.com/drug/cubicin-1342.html
Medically Reviewed by Philip Thornton, DipPharm TheMediTary.Com | Reviewed: Jul 13, 2023  Additional Content by TheMediTary.Com

Generic name: daptomycin [ dap-to-my-sin ]

Drug class: Miscellaneous antibiotics

Dosage form: injection, powder, lyophilized, for solution

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Cubicin rf, Daptomycin

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Cubicin?

Cubicin is an antibiotic that fights bacteria in the body.

Cubicin is used to treat bacterial infections of the skin and underlying tissues, and infections that have entered the bloodstream.

Cubicin is used for complicated infections, including MRSA or "super bug" infections. MRSA stands for methicillin-resistant Staphylococcus aureus.

Warnings

To be sure Cubicin is helping your condition, your blood may need to be tested often. Your kidney function may also need to be tested. Visit your doctor regularly.

If you are using Cubicin at home, be sure you understand how to properly mix and store the medication.

Call your doctor at once if you have a new or worsening cough, fever, trouble breathing, diarrhea that is watery or bloody, muscle pain or weakness, tingly feeling, fever or flu symptoms, dark colored urine, mouth sores, pain or burning when you urinate, urinating less than usual or not at all, pale skin, or feeling light-headed.

How should I take Cubicin

Cubicin is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Do not use Cubicin if you do not understand how to use the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine. Ask your doctor or pharmacist if you have questions.

Cubicin must be given slowly, and the IV infusion can take 2 to 30 minutes to complete. When giving this medicine to a child or teenager, the infusion is even slower (30 to 60 minutes).

Cubicin must be mixed with a liquid (diluent) before using it. Prepare your injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

Do not shake the medication bottle or you may ruin the medicine. Gently swirl the medicine when mixing. Prepare your dose only when you are ready to give an injection. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

You may need frequent blood and urine tests.

This medicine may cause false results with certain medical tests. Tell any doctor who treats you that you are using Cubicin.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Some infections must be treated for up to 6 weeks. Skipping doses can increase your risk of infection that is resistant to medication. Daptomycin will not treat a viral infection such as the flu or a common cold.

Each single-use vial (bottle) of Cubicin is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using daptomycin.

Store Cubicin in the refrigerator. Do not freeze. After mixing with a diluent, store in the refrigerator and use it within 48 hours.

You may also store mixed Cubicin vials for up to 12 hours at room temperature.

Each vial (bottle) is for one use only. Throw it away after one use, even if there is still medicine left inside.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

Dosing information

Usual Adult Dose of Cubicin for Skin and Structure Infection:

4 mg/kg IV every 24 hours for 7 to 14 days

Use: For the treatment of complicated skin and skin structure infections (cSSSI) due to susceptible isolates of Staphylococcus aureus (including methicillin-resistant isolates), Streptococcus pyogenes, S agalactiae, S dysgalactiae subspecies equisimilis, and Enterococcus faecalis (vancomycin-susceptible isolates only)

Usual Adult Dose of Cubicin for Bacteremia:

6 mg/kg IV every 24 hours for 2 to 6 weeks

Comments:
-This drug should not be used for the treatment of left-sided infective endocarditis due to S aureus; in the clinical trial, outcomes were poor.
-This drug has not been studied in patients with prosthetic valve endocarditis.
-Limited safety data regarding use of this drug beyond 28 days

Uses: For the treatment of patients with S aureus bloodstream infections (bacteremia), including those with right-sided infective endocarditis, due to methicillin-susceptible and methicillin-resistant isolates

Usual Adult Dose for Endocarditis:

6 mg/kg IV every 24 hours for 2 to 6 weeks

Comments:
-This drug should not be used for the treatment of left-sided infective endocarditis due to S aureus; in the clinical trial, outcomes were poor.
-This drug has not been studied in patients with prosthetic valve endocarditis.
-Limited safety data regarding use of this drug beyond 28 days

Uses: For the treatment of patients with S aureus bloodstream infections (bacteremia), including those with right-sided infective endocarditis, due to methicillin-susceptible and methicillin-resistant isolates

Usual Pediatric Dose for Skin and Structure Infection:

1 to less than 2 years: 10 mg/kg IV every 24 hours
2 to 6 years: 9 mg/kg IV every 24 hours
7 to 11 years: 7 mg/kg IV every 24 hours
12 to 17 years: 5 mg/kg IV every 24 hours

Duration of therapy: Up to 14 days

Use: For the treatment of cSSSI due to susceptible isolates of S aureus (including methicillin-resistant isolates), S pyogenes, S agalactiae, S dysgalactiae subspecies equisimilis, and E faecalis (vancomycin-susceptible isolates only)

Usual Pediatric Dose for Bacteremia:

1 to 6 years: 12 mg/kg IV every 24 hours
7 to 11 years: 9 mg/kg IV every 24 hours
12 to 17 years: 7 mg/kg IV every 24 hours

Duration of therapy: Up to 42 days

Use: For the treatment of S aureus bloodstream infections (bacteremia)

Detailed Cubicin dosage information
Cubicin Dosage information (more detail)

Before Taking

You should not use Cubicin if you are allergic to daptomycin.

To make sure Cubicin is safe for you, tell your doctor if you have ever had:

  • kidney disease; or

  • a nerve or muscle disorder.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using Cubicin. Ask your doctor about any risk.

Cubicin pregnancy and breastfeeding warnings (more detail)

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Cubicin?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Cubicin side effects

Get emergency medical help if you have signs of an allergic reaction to Cubicin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);

  • fever, flu symptoms, mouth and throat ulcers, rapid heart rate, shallow breathing;

  • pain or burning when you urinate;

  • numbness, tingling, or burning pain in your hands or feet;

  • easy bruising, unusual bleeding;

  • new or worsening cough, fever, trouble breathing; or

  • unexplained muscle pain, tenderness, or weakness.

Common Cubicin side effects may include:

  • chest pain, trouble breathing;

  • headache, dizziness;

  • stomach pain, vomiting;

  • swelling;

  • abnormal liver function tests;

  • rash, itching, sweating;

  • trouble sleeping;

  • sore throat; or

  • increased blood pressure.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Cubicin Side Effects

What other drugs will affect Cubicin?

Tell your doctor about all your other medicines, especially a "statin" cholesterol medicine such as:

  • atorvastatin (Lipitor, Caduet);

  • fluvastatin (Lescol);

  • lovastatin (Mevacor, Altoprev, Advicor);

  • pitavastatin (Livalo);

  • pravastatin (Pravachol);

  • rosuvastatin (Crestor); or

  • simvastatin (Zocor, Simcor, Vytorin);

This list is not complete. Other drugs may interact with daptomycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

More about Cubicin (Daptomycin [ dap-to-my-sin ])

Dosage information
Cubicin Side Effects
During pregnancy
Cubicin Prescribing Information
Drug images
Side effects
Drug class: Miscellaneous antibiotics

Related treatment guides

Skin and Structure Infection
Skin or Soft Tissue Infection
Methicillin-Resistant Staphylococcus Aureus Infection
Bacteremia
Endocarditis
Share this Article
Contents
Uses Warnings Before Taking Dosage Side effects Interactions
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by