In the US, Cyclophosphamide (cyclophosphamide systemic) is a member of the drug class alkylating agents and is used to treat Acute Lymphocytic Leukemia, Acute Nonlymphocytic Leukemia, Bladder Cancer, Brain Tumor, Breast Cancer, Bullous Pemphigoid, Cancer, Cervical Cancer, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Cogan's Syndrome, Dermatomyositis, Diffuse Large B-Cell Lymphoma, Endometrial Cancer, Ewing's Sarcoma, Granulomatosis with Polyangiitis, Histiocytosis, Hodgkin's Lymphoma, Lupus Nephritis, Mantle Cell Lymphoma, Multiple Myeloma, Multiple Sclerosis, Mycosis Fungoides, Nephrotic Syndrome, Neuroblastoma, Non-Hodgkin's Lymphoma, Non-Small Cell Lung Cancer, Organ Transplant - Rejection Prophylaxis, Osteosarcoma, Ovarian Cancer, Pemphigoid, Pemphigus, Primary Immunoglobulin A Nephropathy, Prostate Cancer, Rheumatoid Arthritis, Scleroderma, Small Cell Lung Cancer, Systemic Lupus Erythematosus, Systemic Sclerosis, Testicular Cancer and Wilms' Tumor.

US matches:

• Cyclophosphamide oral and injection
• Cyclophosphamide
• Cyclophosphamide Capsules
• Cyclophosphamide Tablets
• Cyclophosphamide Concentrate Injection
• Cyclophosphamide Injection

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01AA01

CAS registry number (Chemical Abstracts Service)

0000050-18-0

Chemical Formula

C7-H15-Cl2-N2-O2-P

Molecular Weight

261

Therapeutic Categories

Disease-modifying antirheumatic drug, DMARD

Cytostatic alkylating agent

Chemical Name

2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroetyl)tetrahydro-, 2-oxide

Foreign Names

• Cyclophosphamidum (Latin)
• Cyclophosphamid (German)
• Cyclophosphamide (French)
• Ciclofosfamida (Spanish)

Generic Names

• Cyclophosphamide (OS: DCF, BAN)
• B 518 (IS)
• CYP (IS)
• Ledoxina (IS)
• NSC 26271 (IS)
• Cyclophosphamide (PH: Ph. Eur. 9, Ph. Int. 7, USP 41)
• Cyclophosphamide Hydrate (OS: JAN)
• Ciclofosfamide (PH: Ph. Eur. 9)
• Cyclophosphamid (PH: Ph. Eur. 9)
• Cyclophosphamide (PH: BP 2018)
• Cyclophosphamide Hydrate (PH: JP XVII)
• Cyclophosphamidum (PH: Ph. Eur. 9, Ph. Int. 7)

Brand Names

• Alkyloxan
  Human Care, Egypt
• Biodoxan
  Biogalenic, Venezuela
• Ciclofosfamida
  LKM Peru, Peru; Palmagyar, Peru; Perulab, Peru
• Ciclofosfamida 1000 DOSA
  DOSA, Paraguay
• Ciclofosfamida 1000mg Martian
  Kampel Martian, Paraguay
• Ciclofosfamida Dosa
  Dosa, Argentina; Dosa, Uruguay
• Ciclofosfamida Farmaco
  Farmaco Urug., Paraguay
• Ciclofosfamida Filaxis
  GP Pharm, Argentina
• Ciclofosfamida FU
  FU, Uruguay
• Ciclofosfamida Kampar
  Laboratorio Kampar, Chile
• Ciclofosfamida Kemex
  Kemex, Argentina
• Ciclofosfamida Lafedar
  Lafedar, Argentina
• Ciclofosfamida LKM 1000
  LKM, Argentina
• Ciclofosfamida Microsules
  Microsules Arg, Argentina
• Ciklofosfamid Sandoz
  Sandoz, Croatia (Hrvatska)
• Clyclomide
  Pharmedic, Pakistan
• Cyclocel
  Celon, Georgia
• Cyclofosfamide Cadiasun
  Cadiasun, Netherlands
• Cyclofosfamide Sandoz
  Sandoz, Netherlands
• Cyclomide
  Pharmedic, Pakistan
• Cyclophosphamid Sandoz 1000 mg
  Sandoz, Hungary
• Cyclophosphamid Sandoz 500 mg
  Sandoz, Hungary
• Cyclophosphamide
  Baxter Healthcare, United States; IBL Healthcare, Pakistan; Jiangsu Hengrui, United States; West-Ward, United States
• Cyclophosphamide - Hisun Pharm
  Hisun Pfizer Pharmaceuticals, China
• Cyclophosphamide Baxter
  Baxter, New Zealand; Baxter Healthcare, Malta
• Cyclophosphamide Kalbe
  Kalbe, Indonesia
• Cyclophosphamide-Hisun Pharm
  Hisun Pfizer Pharmaceuticals, China
• Cyclophosphan
  Rue Belmedpreparaty, Georgia
• Cyclovid
  Novell Pharmaceutical, Indonesia
• Cycram
  Dbl, Egypt; Korea United, Hong Kong; Korea United Pharm., Vietnam
• Cytoxan
  Bristol-Myers Squibb, Lithuania
• Demacylan
  Sandoz, Poland
• Endoxan
  Almirall, Russian Federation; ASTA Medica, Kuwait; ASTA Medica, Pakistan; Baxter, Bosnia & Herzegowina; Baxter, Chile; Baxter, Cyprus; Baxter, Ecuador; Baxter, Egypt; Baxter, France; Baxter, Lithuania; Baxter, Latvia; Baxter, New Zealand; Baxter, Oman; Baxter, Poland; Baxter, Thailand; Baxter, Tunisia; Baxter, Taiwan; Baxter Belgium, Belgium; Baxter Oncology, Germany; Baxter Oncology, Lebanon; Baxter Oncology, Singapore; Eczacibasi Baxter, Turkey; IFET, Greece; Lex ano, Lithuania; Sanofi-Aventis, South Africa; Transfarma Medica Indah, Indonesia; Baxter Healthcare Trading Shanghai, China
• Endoxan 1g
  Baxter, Luxembourg; Baxter Oncology, Israel
• Endoxan 200mg
  Baxter, Luxembourg
• Endoxan 500mg
  Baxter, Luxembourg; Baxter Oncology, Israel
• Endoxan 50mg
  Baxter, Luxembourg
• Endoxana
  Baxter, Egypt; Baxter, Lebanon
• Endoxan-Asta
  Zydus, India
• Genoxal
  Baxter, Spain
• Genuxal
  Baxter, Brazil
• Hidrofosmin
  Sanfer, Mexico
• Ledoxan
  Fresenius, Philippines
• Ledoxina
  Lemery, Lithuania
• Neophos
  Cipla, Lebanon
• Procytox
  Baxter, Canada; Clinect, New Zealand
• Sendoxan
  Baxter, Denmark; Baxter Medical AB, Iceland
• Syklofosfamid
  Atafarm, Turkey; Orion, Taiwan
• Vf
  Human Care, Egypt
• Xyclomed
  Korea United Pharma, Philippines
• Cryofaxol
  Cryopharma, Mexico
• Cyclonex
  Zenex, Australia
• Cyclophosphamid HEXAL
  Hexal, Germany
• Cyclophosphamide
  Baxter Healthcare, United Kingdom; Sandoz, United Kingdom; Teva, Lithuania
• Cyclophosphamide Sandoz
  Sandoz, France
• Cyclophosphamide Sandoz 1000 mg
  Sandoz, Austria
• Cyclophosphamide Sandoz 2000 mg
  Sandoz, Austria
• Cyclophosphamide Sandoz 500 mg
  Sandoz, Austria
• Demacylan
  Ebewe Pharma, Macedonia
• Endoxan
  Actavis, Romania; Agmar, Croatia (Hrvatska); Baxter, Czech Republic; Baxter, France; Baxter, Hong Kong; Baxter, Hungary; Baxter, Portugal; Baxter, Romania; Baxter, Slovakia; Baxter Healthcare, Australia; Baxter Nederland, Netherlands; Baxter Oncology, Estonia; Baxter Oncology, Macedonia; Baxter Oncology GmbH, Serbia; Dr. Fisher Farma, Netherlands; Shionogi Seiyaku, Japan
• Endoxan 1 g
  Baxter, Hungary
• Endoxan 1g
  Baxter, Switzerland; Baxter Oncology, Bulgaria
• Endoxan 200mg
  Baxter, Switzerland; Baxter Oncology, Bulgaria
• Endoxan 500 mg
  Baxter, Hungary
• Endoxan 500mg
  Baxter, Switzerland; Baxter Oncology, Bulgaria
• Endoxan 50mg
  Baxter, Switzerland; Baxter Oncology, Bulgaria
• Endoxan Baxter
  Baxter-RM, Italy
• Endoxan Baxter 1 g
  Baxter Healthcare, Austria
• Endoxan Baxter 200 mg
  Baxter Healthcare, Austria
• Endoxan Baxter 50 mg
  Baxter Healthcare, Austria
• Endoxan Baxter 500 mg
  Baxter Healthcare, Austria
• Endoxana
  Baxter, Ireland
• Formitex
  Pisa, Mexico
• Formitex Pisa
  Pisa, Colombia
• Ledoxina
  Teva, Mexico
• Sendoxan
  Baxter, Finland; Baxter, Norway; Baxter, Sweden

Glossary

Further information on drug naming conventions: International Nonproprietary Names.