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Home > Drugs > Antibiotics / antineoplastics > Daunorubicin
Antibiotics / antineoplastics

Daunorubicin

https://themeditary.com/drug/daunorubicin-6666.html
Medically Reviewed by Glamora Samuels, MD TheMediTary.Com | Reviewed: Aug 14, 2023  Additional Content by TheMediTary.Com

Generic name: daunorubicin [ daw-noe-roo-bi-sin ]

Drug class: Antibiotics / antineoplastics

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Daunorubicin?

Daunorubicin is used in combination chemotherapy to treat leukemia.

Daunorubicin may also be used for purposes not listed in this medication guide.

Warnings

Daunorubicin may cause dangerous effects on your heart, and can also increase your risk of bleeding or infection. Call your doctor at once if you have chest pain, shortness of breath, swelling or rapid weight gain, fever, chills, tiredness, easy bruising or unusual bleeding.

How should I take Daunorubicin

Daunorubicin comes as a solution (liquid) or as a powder to be mixed with liquid to be injected intravenously (into a vein) by a doctor or nurse in a medical facility along with other chemotherapy medications. When daunorubicin is used to treat AML, it is usually injected once a day on certain days of your treatment period. When daunorubicin is used to treat ALL, it is usually injected once a week. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Dosing information

Daunorubicin is given as an infusion into a vein. A healthcare provider will give you this injection.

Before you receive each dose of daunorubicin, your heart function may need to be checked with an electrocardiograph or ECG (sometimes called an EKG). Your kidney and liver function may also need to be checked.

You may be given other medications to help prevent serious side effects or an allergic reaction. Keep using these medicines for as long as your doctor has prescribed.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when daunorubicin is injected.

Skin accidentally exposed to daunorubicin should be rinsed thoroughly with soap and warm water.

Daunorubicin can increase your risk of bleeding or infection. You will need frequent medical tests. Your cancer treatments may be delayed based on the results of these tests.

Detailed Daunorubicin dosage information
Daunorubicin Dosage information (more detail)

Before Taking

You should not use daunorubicin if you are allergic to it.

Tell your doctor if you have ever had:

  • heart disease;

  • kidney disease;

  • liver disease;

  • a weak immune system (caused by disease or by using certain medicines); or

  • if you have ever been treated with doxorubicin, epirubicin, idarubicin, mitoxantrone, or liposomal daunorubicin (Daunoxome).

Using daunorubicin may increase your risk of developing other types of leukemia. Ask your doctor about your specific risk.

Daunorubicin may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

You should not breastfeed while using daunorubicin.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your daunorubicin injection.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I avoid while using Daunorubicin?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Daunorubicin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Daunorubicin may cause serious side effects. Call your doctor at once if you have:

  • pain, burning, irritation, or skin changes where the injection was given;

  • heart problems--swelling, rapid weight gain, feeling short of breath;

  • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed;

  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired; or

  • liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of daunorubicin may include:

  • sores or white patches in or around your mouth, trouble swallowing or talking, dry mouth, bad breath, altered sense of taste;

  • red discoloration of the urine;

  • nausea, vomiting; or

  • hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Daunorubicin Side Effects

What other drugs will affect Daunorubicin?

Daunorubicin can harm your liver, especially if you also use certain medicines for infections, tuberculosis, birth control, hormone replacement, high cholesterol, heart problems, high blood pressure, seizures, pain, or arthritis (including Tylenol, Advil, Motrin, or Aleve).

Other drugs may affect daunorubicin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What other information should I know?

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

More about Daunorubicin (Daunorubicin [ daw-noe-roo-bi-sin ])

Dosage information
Daunorubicin Side Effects
During pregnancy
Drug images
Side effects
Drug class: Antibiotics / antineoplastics

Related treatment guides

Acute Nonlymphocytic Leukemia
Acute Lymphocytic Leukemia
Acute Myeloid Leukemia
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