Dexamethasone is a steroid medicine used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, breathing disorders, eye conditions, blood cell disorders, leukemia, multiple sclerosis, inflammation of the joints or tendons, and problems caused by low adrenal gland hormone levels.

Dexamethasone may also be used for purposes not listed in this medication guide.

You should not be treated with dexamethasone if you are allergic to it, or if you have:

• a fungal infection anywhere in your body.

Steroids can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have. Tell your doctor about any illness or infection you had within the past several weeks.

Tell your doctor if you have ever had:

• liver disease (such as cirrhosis);
• kidney disease;
• a thyroid disorder;
• a parasite infection that causes diarrhea (such as threadworms);
• tuberculosis;
• osteoporosis;
• a muscle disorder such as myasthenia gravis;
• diabetes (steroid medicine may increase glucose levels in your blood or urine);
• glaucoma or cataracts;
• herpes infection of the eyes;
• stomach ulcers, ulcerative colitis, diverticulitis, inflammatory bowel disease;
• depression or mental illness;
• congestive heart failure, a heart attack; or
• high blood pressure.

Tell your doctor if you are pregnant or breastfeeding.

Use Dexone (Injectable) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• fever, chills, tiredness;
• worsening pain, swelling, or stiffness of a joint treated with this medicine;
• muscle weakness, limp feeling;
• swelling, rapid weight gain, feeling short of breath;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• bloody or tarry stools, coughing up blood;
• a seizure;
• increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;
• pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting; or
• low blood potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.

Dexamethasone can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

• fluid retention (swelling in your hands or ankles);
• headache, dizziness;
• increased blood pressure;
• slow wound healing;
• acne, thinning skin, bruising or discoloration;
• changes in your menstrual periods; or
• changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using steroid medicine.

Avoid drinking alcohol while you are taking dexamethasone.

Avoid receiving a "live" vaccine, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Avoid receiving any other type of vaccine without your doctor's advice, including a yearly flu shot.