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Home > Drugs > Dolutegravir And Rilpivirine
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Dolutegravir And Rilpivirine

https://themeditary.com/drug/dolutegravir-and-rilpivirine-15931.html
Medically Reviewed by Glamora Samuels, MD TheMediTary.Com | Reviewed: Sep 22, 2023  Additional Content by TheMediTary.Com

Pregnancy & Lactation: Risk data not available

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Dolutegravir And Rilpivirine?

Dolutegravir and rilpivirine is a combination antiviral medicine used to treat HIV, the virus that can cause the acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS.

Dolutegravir and rilpivirine is for use only in people who have been successfully treated with other antiviral medications for at least 6 months.

Dolutegravir and rilpivirine may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if you are allergic to dolutegravir or rilpivirine.

Some medicines can cause unwanted or dangerous effects when used with dolutegravir and rilpivirine. Your doctor may change your treatment plan if you also use:

  • dofetilide (can cause serious medical problems or death when taken with dolutegravir and rilpivirine);
  • St John's wort;
  • more than one dose of dexamethasone;
  • carbamazepine, oxcarbazepine, phenobarbital, phenytoin;
  • rifampin, rifapentine; or
  • esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole.

Tell your doctor if you have ever had:

  • liver problems;
  • mental illness;
  • a severe skin rash or allergic reaction to dolutegravir or rilpivirine; or
  • if you also take rifabutin.

You may need to have a negative pregnancy test before starting this treatment.

Dolutegravir and rilpivirine may harm an unborn baby if you take the medicine at the time of conception or during the first 12 weeks of pregnancy. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

HIV can be passed to your baby if the virus is not controlled during pregnancy. If you are pregnant, your name may be listed on a registry to track any effects of antiviral medicine on the baby. Use your medications properly to control HIV.

Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

How should I use Dolutegravir And Rilpivirine

Use Dolutegravir And Rilpivirine (Juluca) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Always take this medicine with food, not with a meal replacement drink.

You will need frequent blood tests.

Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with any packet or canister of moisture-absorbing preservative.

What should I do if I missed a dose of Dolutegravir And Rilpivirine (Juluca)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Get your prescription refilled before you run out of medicine completely.

Dolutegravir And Rilpivirine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Call your doctor at once if you have:

  • thoughts about suicide or hurting yourself;
  • anxiety, sadness, feeling hopeless;
  • depression--mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, new sleep problems, thoughts about hurting yourself; or
  • liver problems--nausea, vomiting, loss of appetite, right-sided upper stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Dolutegravir and rilpivirine affects your immune system, which may cause certain side effects (even weeks or months after you've taken this medicine). Tell your doctor if you have:

  • signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;
  • trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or
  • swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.

Common side effects may include:

  • headache; or
  • nausea, diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Dolutegravir And Rilpivirine?

Using this medicine will not prevent your disease from spreading. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

More about Dolutegravir And Rilpivirine

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