Generic name: Morphine (injection)
Pregnancy & Lactation: Risk data not available
What is Duramorph PF?
Morphine is an opioid medicine used to treat severe chronic pain in adults and children.
Morphine may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you have ever had an allergic reaction to morphine or other opioid medicines, or if you have:
- severe asthma or breathing problems;
- a stomach or bowel obstruction (including paralytic ileus); or
- if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.
Tell your doctor if you have ever had:
- breathing problems, sleep apnea (breathing that stops during sleep);
- a head injury, brain tumor, or seizures;
- a drug or alcohol addiction, or mental illness;
- urination problems;
- liver or kidney disease; or
- pancreatitis.
If you use opioid medicine during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.
Ask a doctor before using opioid medicine if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.
How should I use Duramorph PF
Use Duramorph PF (Injectable) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow the directions on your prescription label and read all medication guides or instruction sheets. Never use morphine in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine.
Never share opioid medicine with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.
Morphine is injected into a muscle or a vein. Morphine injection is sometimes given with an infusion pump that controls your dosing.
You may have withdrawal symptoms if you stop using morphine suddenly. Ask your doctor before stopping the medicine.
Store at room temperature away from moisture and heat. Keep the auto-injector in its original container until you are ready to use it.
Keep your medicine in a place where no one can use it improperly.
Do not keep leftover medicine. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist about a drug take-back program, or flush the unused medicine down the toilet.
Because you will receive morphine in a hospital or with a controlled infusion pump, you are not likely to miss a dose.
Duramorph PF side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Call your doctor at once if you have:
- slow heart rate, sighing, shallow breathing, breathing that stops;
- extreme drowsiness, feeling like you might pass out;
- flushing (sudden warmth, redness, or tingly feeling);
- a seizure;
- high levels of serotonin in the body--agitation, hallucinations, fever, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, diarrhea; or
- low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Serious breathing problems may be more likely in older adults and people who are debilitated or have wasting syndrome or chronic breathing disorders.
Common side effects may include:
- breathing problems;
- drowsiness, dizziness;
- constipation, nausea, vomiting;
- sweating; or
- numbness, tingling, or cold feeling in your hands and feet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Duramorph PF?
Do not drink alcohol. Dangerous side effects or death could occur.
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.