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Home > Drugs > Duvyzat
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Duvyzat

https://themeditary.com/drug/duvyzat-23484.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Sep 23, 2024  Additional Content by TheMediTary.Com

Generic name: Givinostat

Pregnancy & Lactation: Risk data not available

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Duvyzat?

Givinostat is used to treat Duchenne muscular dystrophy in adults and children at least 6 years old.

Givinostat may also be used for purposes not listed in this medication guide.

Warnings

Givinostat can cause a serious heart problem. Your treatment plan may change if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Tell your doctor about all other medicines you use.

Tell your doctor if you have or have ever had:

  • heart problems, heart rhythm disorders; or
  • bleeding problems.

It is not known if givinostat will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

How should I use Duvyzat

Use Duvyzat (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Doses are based on weight. Your dose may change if you gain or lose weight.

Givinostat is usually taken twice per day with food.

Do not mix this medicine with water or with any other liquids.

You may be given medication to prevent diarrhea or vomiting while you are receiving givinostat.

You may need medical tests before and during your treatment with this medicine, and your dose may be changed based on the results.

Gently swirl the oral suspension (liquid) for at least 30 seconds. Measure a dose with the supplied measuring device (not a kitchen spoon).

Store tightly closed in an upright position at room temperature, do not freeze. Throw the medicine away after 60 days of first opening the bottle, even if there is still medicine left inside.

What should I do if I missed a dose of Duvyzat (Oral)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Duvyzat side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Givinostat can make it easier for you to bleed, even from a minor injury. Call your doctor if you have bleeding that will not stop. Bleeding may also happen inside your body, such as in your stomach or intestines, or in your brain.

Call your doctor at once if you have:

  • severe or ongoing diarrhea;
  • irregular heartbeats;
  • long QT syndrome (in you or a family member);
  • coronary artery disease (clogged arteries);
  • an electrolyte imbalance (such as low blood levels of potassium or magnesium);
  • dizziness, fainting; or
  • loss of consciousness.

Your treatment with givinostat may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

  • nausea, vomiting, stomach pain;
  • loose stools or diarrhea that is watery;
  • fever;
  • high cholesterol or triglycerides; or
  • low levels of platelets in your blood.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Duvyzat?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

More about Duvyzat (Givinostat)

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Drug class: Drugs
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions
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