Pregnancy & Lactation: Risk data not available
What is Eplontersen?
Eplontersen is used to treat nerve problems in adults with amyloidosis (a rare disease occurring when a protein called amyloid builds up).
Eplontersen may also be used for purposes not listed in this medication guide.
Warnings
Tell your doctor if you take:
- beta-carotene supplements or vitamin A.
Tell your doctor if you are pregnant or breastfeeding.
How should I use Eplontersen
Use Eplontersen (Subcutaneous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Eplontersen is injected under the skin. A healthcare provider may give you this injection or may teach you how to properly use this medicine by yourself.
Ask your doctor or pharmacist if you don't understand how to use an injection.
Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.
Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.
You may need frequent vision exams.
You may need to take vitamin A supplements while using eplontersen.
Follow all storage instructions provided with eplontersen. Your pharmacist can provide more information about how to store this medicine.
Use eplontersen as soon as you can. Then use this medicine 1 month from your last dose to return to a monthly dosing schedule. Do not use two doses at one time.
Eplontersen side effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- vision problems--trouble seeing at night or in low lit areas (night blindness), or dry eyes.
Common side effects may include:
- eye problems;
- dry skin; or
- vomiting.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Eplontersen?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.