Erythromycin is an antibiotic that fights bacteria.

Erygel (for the skin) is used to treat acne vulgaris in adults.

Erygel may also be used for purposes not listed in this medication guide.

Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin.

Wash your hands before and after using Erygel.

Clean and dry the skin area before you apply Erygel. Spread the medicine on lightly, without rubbing it in.

Erygel is usually applied once or twice daily. Follow your doctor's instructions.

Store at room temperature away from moisture and heat. Keep the tube or bottle tightly closed when not in use.

Erygel gel is flammable. Do not use near high heat or open flame. Do not smoke until the gel has completely dried on your skin.

You should not use Erygel if you are allergic to it.

Tell your doctor if you are pregnant or breastfeeding.

Erygel is not approved for use by anyone younger than 18 years old.

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Avoid using other medications on the areas you treat with Erygel unless your doctor tells you to.

Avoid using skin products that can cause irritation, such as harsh soaps or skin cleansers, or skin products with alcohol, spices, astringents, or lime.

Avoid getting this medication in your eyes, mouth, and nose. If it does get into any of these areas, rinse with water.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Erygel may cause serious side effects. Call your doctor at once if you have:

• severe burning, stinging, or redness;

• oozing or other signs of skin infection;

• worsening of your skin condition; or

• severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose).

Common side effects of Erygel may include:

• skin itching, redness, burning, or peeling; or

• dry or oily skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.