Flutamide is used to treat prostate cancer.

Flutamide is given in combination with another medicine called a luteinizing (LOO-tee-in-ize-ing) hormone-releasing hormone, or LHRH. LHRH helps prevent the testicles from producing testosterone.

Flutamide may also be used for purposes not listed in this medication guide.

You should not use flutamide if you are allergic to it, or if you have severe liver problems.

Flutamide should never be taken by a woman or a child.

Tell your doctor if you have ever had:

• liver disease;
• a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;
• hemoglobin M disease;
• if you smoke; or
• if you also take a blood thinner (warfarin, Coumadin, Jantoven).

Although flutamide is not for use by women, this medicine can cause birth defects if a woman is exposed to it during pregnancy.

Use Eulexin (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Flutamide can cause serious liver problems. Call your doctor at once if you have:

• nausea, upper stomach pain, loss of appetite;
• itching, tiredness, flu-like symptoms;
• dark urine, clay-colored stools; or
• jaundice (yellowing of the skin or eyes).

Common side effects may include:

• breast swelling or tenderness;
• hot flashes;
• vomiting, nausea, diarrhea; or
• impotence, loss of interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

To help prevent diarrhea, avoid dairy products such as milk, cheese, and yogurt. Do not use laxatives while taking flutamide.