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Home > Drugs > Ophthalmic steroids > Eysuvis
Ophthalmic steroids

Eysuvis

https://themeditary.com/drug/eysuvis-8340.html
Medically Reviewed by Philip Thornton, DipPharm TheMediTary.Com | Reviewed: Aug 29, 2023  Additional Content by TheMediTary.Com

Generic name: loteprednol etabonate

Drug class: Ophthalmic steroids

Dosage form: eye (suspension) drops

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Inveltys (ophthalmic), Lotemax, Alrex (ophthalmic), Loteprednol (ophthalmic), Lotemax

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Eysuvis?

Eysuvis (loteprednol etabonate) is a prescription corticosteroid eye drop used for the short-term treatment of dry eye disease.

People with dry eye disease make poor quality tears or not enough tears, which can cause red, burning and scratchy eyes. It can also cause eyes to become teary and result in blurred vision.

Eysuvis works by blocking inflammation, which is a key driver of dry eye flare-ups.

Eysuvis is a suspension eye drop that makes use of a drug delivery technology called Ampplify, which allows the medication to better penetrate the mucus barrier on your eyes, leading to increased amounts of the corticosteroid medication reaching the affected area.

Eysuvis was the first corticosteroid eye drop to be approved by the US Food and Drug Administration (FDA) for the short-term treatment of dry eye disease when it was approved in 2020.

What is Eysuvis used for?

Eysuvis is used for the short-term (up to two weeks) treatment of the signs and symptoms of dry eye disease.

Warnings

Eysuvis is for use in the eyes.

Eysuvis may cause serious side effects.

  • Intraocular pressure (IOP) increase
    • Prolonged use of ophthalmic corticosteroids can cause an increase in the pressure in your eyes and may result in glaucoma and damage to your eyes. Your doctor should examine your eyes before you start using this medication to check for increased eye pressure.
  • Cataracts
    • Use of ophthalmic corticosteroids may result in posterior subcapsular cataract formation.
  • Delayed healing
    • Use of ophthalmic corticosteroids may delay healing. Your doctor should examine your eyes before you start using this medications and before each renewal of your prescription to check for signs of damage to the surface of your eyes.
  • Viral infections
    • Ophthalmic corticosteroids may prolong viral eye infections and make them more severe. Use of ocular steroids should not be used in most viral eye infections and should be used with great caution in people with a history of herpes simplex.
  • Bacterial infections
    • Ophthalmic corticosteroids should not be used in mycobacterial infection of the eye. They may also suppress your immune response increases your chances of a secondary infection, mask an infection or enhance an existing infection.
  • Fungal infections
    • Long-term use of corticosteroid eye drops can increase your chances of a fungal infection of the cornea. Persistent corneal ulceration when using corticosteroid eye drops may be a sign of a fungal infection.

Remove contact lenses before using Eysuvis. Contact lenses may be reinserted 15 minutes later.

How should I take Eysuvis

  • Use Eysuvis eye drops exactly as your healthcare provider tells you to.
  • If you are wearing contact lenses take them out before using Eysuvis. The preservative in this medication can be absorbed by soft contact lenses. Contact lenses may be reinstered 15 minutes after putting the eye drops in.
  • If you are using other eye medications, wait at least 5 minutes before using them after using Eysuvis.
  • Eysuvis can be used as soon as your feel the symptoms of a dry eye flare-up coming on.
  • Eysuvis is for short-term use for up to 2 weeks at a time.
  • Remove the outer cap on bottle by twisting it clockwise.
  • Wash your hands.
  • Shake the bottle for two to three seconds before using.
  • Remove the inner pick cap. Do not allow the dropper tip to touch any surface, as this may contaminate the suspension.
  • Put 1 to 2 drops into the affected eye up to 4 times a day.
  • Put the pink cap back on the bottle.
  • Contact your healthcare provider if pain develops, or redness, itching or inflammation become aggravated. These can be signs of infection.

Dosing information

The recommended dose of Eysuvis is 1 to 2 drops into each eye four times daily for up to two weeks.

Detailed Eysuvis dosage information
Eysuvis Dosage information (more detail)

Before Taking

Do not use Eysuvis if:

  • you are allergic to any of the ingredients in Eysuvis. See below for a complete list of ingredients.
  • you have a viral infection of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella.
  • you have a mycobacterial infection of the eye
  • you have a fungal disease affecting ocular structures.
Eysuvis pregnancy and breastfeeding warnings (more detail)

What should I tell my doctor before using Eysuvis?

Before using Eysuvis, tell your healthcare provider about all your medical conditions including if you have or had:

  • an eye infection
  • increased eye pressures or glaucoma
  • cataracts or cataract surgery

What happens if I miss a dose?

If you miss a dose of Eysuvis then take a dose when you remember.

Eysuvis side effects

Eysuvis may cause serious side effects. See "Important information" above.

The most common side effect of Eysuvis after using it for two weeks was instillation site pain, which was reported in 5 percent of patients.

This is not the only possible side effect of Eysuvis. Call your doctor for advice about side effects.

To report suspected adverse reactions, contact Kala Pharmaceuticals, Inc. at 1-833-287-KALA (1-833-287-5252) or FDA at 1-800-FDA-1088 or. www.fda.gov/medwatch.

See more: Eysuvis Side Effects

What other drugs will affect Eysuvis?

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

More about Eysuvis (Loteprednol etabonate)

Dosage information
Eysuvis Side Effects
During pregnancy
Eysuvis Prescribing Information
Drug images
Side effects
Breastfeeding Warnings
Drug class: Ophthalmic steroids

Related treatment guides

Dry Eye Disease
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