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Home > Drugs > Antihistamines > Fexofenadine
Antihistamines

Fexofenadine

https://themeditary.com/drug/fexofenadine-280.html
Medically Reviewed by Carmen Pope, BPharm TheMediTary.Com | Reviewed: Jul 10, 2023  Additional Content by TheMediTary.Com

Generic name: fexofenadine [ fex-oh-fen-a-deen ]

Drug class: Antihistamines

Availability: Rx and/or otc

Pregnancy & Lactation: Risk data available

Brand names: Allegra, Children's allegra allergy, Children's allegra odt, Allegra 12 hour allergy, Allegra 24 hour allergy

Contents
Uses Warnings Before Taking Dosage Side effects Interactions
  • Fexofenadine (Fexofenadine [ fex-oh-fen-a-deen ])-7251 93-30 mg-Orange-Oval Fexofenadine 30 mg (7251 93)
  • Fexofenadine (Fexofenadine [ fex-oh-fen-a-deen ])-7252 93-60 mg-Orange-Round Fexofenadine 60 mg (7252 93)
  • Fexofenadine (Fexofenadine [ fex-oh-fen-a-deen ])-93 7253-180 mg-Orange-Round Fexofenadine 180 mg (93 7253)
  • Fexofenadine (Fexofenadine [ fex-oh-fen-a-deen ])-03-30 mg-Orange-Round Fexofenadine 30 mg (03)
  • View all images

What is Fexofenadine?

Fexofenadine is an antihistamine that may be used to treat allergy symptoms (including hay fever) in adults and children.

Fexofenadine is also used to treat skin itching and hives caused by a condition called chronic idiopathic urticaria in adults and children who are at least 6 years old.

Fexofenadine works selectively on histamine-1 receptors that are located in our body, but not in our central nervous system - these are called peripheral histamine receptors. Because it acts on these receptors, fexofenadine is much less likely to cause drowsiness compared with some older antihistamines.

Histamine is a chemical that is released by mast cells in response to an allergen, and it is responsible for many allergy symptoms, such as watery eyes, a runny nose, sneezing, and itching. Fexofenadine binds to histamine receptors and prevents histamine from having an effect on those receptors, which reduces allergy symptoms.

There are many brands and forms of fexofenadine available.

Fexofenadine was FDA approved in 1996.

Warnings

Do not take fexofenadine with fruit juice (such as apple, orange, or grapefruit).

Before taking this medicine

You should not use fexofenadine if you are allergic to it.

Ask a doctor or pharmacist if fexofenadine is safe to use if you have:

  • kidney disease.

Ask a doctor before using fexofenadine if you are pregnant or breastfeeding.

Older adults may be more sensitive to the effects of this medicine. If you are 65 or older, ask a doctor before taking fexofenadine.

This medicine may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

Fexofenadine pregnancy and breastfeeding warnings (more detail)

How should I take Fexofenadine

Fexofenadine comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken with water once or twice a day. Fexofenadine will work better if it is not taken with fruit juices such as orange, grapefruit, or apple juice. Take fexofenadine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fexofenadine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Fexofenadine controls the symptoms of seasonal allergic rhinitis and urticaria but does not cure these conditions. Continue to take fexofenadine even if you feel well and are not experiencing these symptoms. If you wait too long between doses, your symptoms may become worse.

Shake the suspension well before each use to mix the medication evenly.

Dosing information

Take fexofenadine exactly as directed on the label, or as prescribed by your doctor.

Always follow directions on the medicine label about giving cough or cold medicine to a child.

  • Ask a doctor before giving fexofenadine liquid to a child younger than 2 years old.

  • The disintegrating (melting) tablets are not for use in a child younger than 6 years old.

  • The 12-hour and 24-hour forms of fexofenadine are not for use in a child younger than 12 years old.

Take this medicine only with water.

Take the disintegrating tablet on an empty stomach.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing cup provided, or use a medicine dose-measuring device (not a kitchen spoon).

Fexofenadine orally disintegrating tablets should only be removed from the package just before you are going to take them. Place the tablet on your tongue and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.

Call your doctor if your symptoms do not improve, or if they get worse.

Store fexofenadine in its original package at room temperature, away from moisture and heat. Do not allow liquid medicine to freeze.

Detailed Fexofenadine dosage information
Fexofenadine Dosage information (more detail)

Before Taking

You should not use fexofenadine if you are allergic to it.

Ask a doctor or pharmacist if fexofenadine is safe to use if you have:

  • kidney disease.

Ask a doctor before using fexofenadine if you are pregnant or breastfeeding.

Older adults may be more sensitive to the effects of this medicine. If you are 65 or older, ask a doctor before taking fexofenadine.

This medicine may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

Fexofenadine pregnancy and breastfeeding warnings (more detail)

Related/similar drugs

prednisone, fluticasone nasal, cetirizine, loratadine, Benadryl, promethazine, Zyrtec

What happens if I miss a dose?

Fexofenadine is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms of fexofenadine may include a dry mouth, dizziness, or drowsiness.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I avoid while using Fexofenadine?

Do not take fexofenadine with fruit juice (such as apple, orange, or grapefruit). These juices can make it harder for your body to absorb fexofenadine.

Avoid taking an antacid within 2 hours before or after you take fexofenadine. Do not use fexofenadine at the same time as antacids that contain magnesium or aluminum.

Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.

Fexofenadine side effects

Get emergency medical help if you have signs of an allergic reaction to fexofenadine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Fexofenadine may cause serious side effects. Stop using fexofenadine and call your doctor at once if you have:

  • flu-like symptoms (fever, chills, unusual tiredness);

  • new or worsening cough;

  • pain; or

  • signs of an ear infection--fever, ear pain or full feeling, trouble hearing, drainage from the ear, fussiness in a child.

Common side effects of fexofenadine may include:

  • headache;

  • back pain; or

  • cold symptoms such as stuffy nose, sinus pain, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Fexofenadine Side Effects

What other drugs will affect Fexofenadine?

Using fexofenadine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Ask a doctor or pharmacist before using fexofenadine with any other medications, especially:

  • ketoconazole; or

  • erythromycin.

This list is not complete. Other drugs may affect fexofenadine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

More about Fexofenadine (Fexofenadine [ fex-oh-fen-a-deen ])

Dosage information
Fexofenadine Side Effects
Patient tips
During pregnancy
Drug images
Side effects
Drug class: Antihistamines

Patient resources

Fexofenadine Orally Disintegrating Tablets
Fexofenadine Oral Suspension
Fexofenadine Tablets

Related treatment guides

Urticaria
Physical Urticaria
Allergic Rhinitis
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