Flurbiprofen is a nonsteroidal anti-inflammatory drugs (NSAID).

Flurbiprofen ophthalmic (for the eye) is used to keep your pupils from constricting, or narrowing, during eye surgery.

Flurbiprofen ophthalmic may also be used for purposes not listed in this medication guide.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Flurbiprofen ophthalmic is usually given every 30 minutes beginning 2 hours before your surgery.

Wash your hands before using eye medication.

To apply the eye drops: Pull down your lower eyelid to create a small pocket and squeeze a drop into this pocket. Close your eyes for 1 or 2 minutes.

Use only the prescribed number of drops. Use in both eyes only if your doctor has told you to.

Do not touch the dropper tip or place it directly on your eye. A contaminated dropper can infect your eye and lead to serious vision problems.

If using this medicine in both eyes: You may be given 2 bottles of flurbiprofen ophthalmic. Assign a separate bottle to each eye, and use only that bottle in that eye (left or right).

Store at room temperature away from moisture and heat. Keep the bottle(s) tightly closed when not in use.

Usual Adult Dose for Inhibition of Intraoperative Miosis:

A total of 4 drops administered by instilling 1 drop approximately every half hour beginning 2 hours before surgery

Use: Inhibition of intraoperative miosis

You should not use this flurbiprofen if you are allergic to it.

Tell your doctor if you have ever had:

• a bleeding or blood-clotting disorder; or

• asthma; or

• a severe reaction of sneezing, runny or stuffy nose, or wheezing after taking aspirin or another NSAID (aspirin, ibuprofen, indomethacin, naproxen, Advil, Motrin, Aleve, and others).

It is not known if flurbiprofen will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using flurbiprofen ophthalmic.

Not approved for use by anyone younger than 18 years old.

Call your doctor for instructions if you miss the dose given before your surgery. The 2-hour timing is very important for flurbiprofen ophthalmic to be effective.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medicine.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unless your doctor tells you otherwise, continue your normal diet.

Do not wear any contact lens that has not been approved by your doctor.

Do not use other eye medications unless your doctor tells you to.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Flurbiprofen ophthalmic may cause serious side effects. Call your doctor at once if you have:

• eye pain or redness;

• an appearance of blood inside your eye;

• vision changes (your eyes may be more sensitive to light); or

• severe burning, stinging, or itching of your eyes.

Common side effects of flurbiprofen ophthalmic may include:

• mild burning or stinging; or

• blurred or hazy vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all your other medicines, especially:

• a blood thinner--warfarin, Coumadin, Jantoven; or

• steroid medicine used in the eyes--dexamethasone, difluprednate, fluocinolone, fluorometholone, hydrocortisone, prednisolone, and others.

Other drugs may affect flurbiprofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Keep all appointments with your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.