Fosfomycin is an antibiotic that fights infection caused by bacteria.

Fosfomycin is used to treat bladder infections.

Fosfomycin may also be used for purposes not listed in this medication guide.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Fosfomycin is usually given in only one dose. Do not take more than a single dose unless your doctor tells you to.

You may take fosfomycin with or without food.

Fosfomycin is a powder medicine that must be mixed with water before using it. Do not take the dry powder without adding water.

Dissolve the powder in 3 to 4 ounces (1/2 cup) of cold water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Do not mix fosfomycin oral powder with hot water.

It may take 2 or 3 days before your symptoms improve.

Call your doctor if your symptoms do not improve within 3 days after treatment, or if you have any other new symptoms.

To be sure fosfomycin is the right antibiotic for the type of infection you have, your urine may need to be tested before and after you take this medicine.

Store at room temperature away from moisture and heat. Keep the powder in its original package until you are ready to mix your dose.

Usual Adult Dose for Cystitis:

3 g (1 sachet) orally once as a single dose

Comments:
-This drug should not be used for the treatment of pyelonephritis or perinephric abscess.

Use: For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis

Usual Adult Dose for Urinary Tract Infection:

3 g (1 sachet) orally once as a single dose

Comments:
-This drug should not be used for the treatment of pyelonephritis or perinephric abscess.

Use: For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis

You should not use fosfomycin if you are allergic to it.

Tell your doctor if you are pregnant or breastfeeding.

Fosfomycin should not be given to a child younger than 12 years old.

Do not share fosfomycin with another person, even if they have the same symptoms you have.

Fosfomycin is used as a single dose and does not have a daily dosing schedule.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include hearing problems and altered sense of taste.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Antibiotic medicines can cause diarrhea. Tell your doctor if you have diarrhea that is watery or bloody.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Fosfomycin may cause serious side effects. Call your doctor at once if you have:

• diarrhea that is watery or bloody; or

• new or worsening bladder symptoms (burning, painful urination).

Common side effects of fosfomycin may include:

• nausea, upset stomach, stomach pain, diarrhea;

• headache, dizziness;

• weakness;

• rash;

• sore throat, runny nose;

• back pain; or

• menstrual pain, vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all your other medicines, especially metoclopramide.

Other drugs may affect fosfomycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to fosfomycin

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the fosfomycin, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.