Generic name: Floxuridine
Pregnancy & Lactation: Risk data not available
What is FUDR?
Floxuridine is used to treat digestive system cancers that have spread to the liver.
Floxuridine may also be used for purposes not listed in this medication guide.
Warnings
You should not be treated with floxuridine if you have:
- an infection;
- bone marrow suppression; or
- if you are malnourished.
Tell your doctor if you have ever had:
- liver disease;
- kidney disease;
- radiation of your pelvic area; or
- treatment with other chemotherapy medicines.
Floxuridine may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
You should not breastfeed while using this medicine.
How should I use FUDR
Use FUDR (Injectable) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
You may receive your first dose in a hospital or clinic setting to quickly treat any serious side effects.
Floxuridine is injected into an artery through an infusion pump. A healthcare provider will give you this injection.
You will be watched closely while receiving floxuridine, to make sure you do not have a severe reaction.
Floxuridine can increase your risk of bleeding or infection. You will need frequent medical tests. Your cancer treatments may be delayed based on the results.
Because you will receive floxuridine in a clinical setting, you are not likely to miss a dose.
FUDR side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- chest pain or pressure;
- blisters or ulcers in your mouth, red or swollen gums, trouble swallowing;
- fever, chills, sore throat, mouth sores, feeling light-headed;
- severe vomiting or diarrhea;
- bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
- easy bruising, unusual bleeding, purple or red spots under your skin; or
- any bleeding that will not stop.
Common side effects may include:
- nausea, vomiting, diarrhea, stomach cramps;
- stomatitis;
- abnormal blood tests; or
- redness or irritation where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect FUDR?
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Do not receive a "live" vaccine while using floxuridine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.