Pregnancy & Lactation: Risk data not available
What is Glecaprevir And Pibrentasvir?
Glecaprevir and pibrentasvir is a combination antiviral medicine used to treat chronic hepatitis C in people with HCV genotype 1, 2, 3, 4, 5, or 6.
Glecaprevir and pibrentasvir is usually given after other treatments have failed.
Glecaprevir and pibrentasvir may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you are allergic to glecaprevir or pibrentasvir, or if:
- you have liver disease; or
- you also take atazanavir or rifampin.
Tell your doctor if you have ever had:
- hepatitis B;
- liver problems other than hepatitis;
- a liver or kidney transplant;
- HIV (human immunodeficiency virus); or
- an opioid addiction or past use of injected drugs.
Tell your doctor if you are pregnant or breastfeeding.
Glecaprevir and pibrentasvir should not be given to a child younger than 3 years old.
How should I use Glecaprevir And Pibrentasvir
Use Glecaprevir And Pibrentasvir (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using glecaprevir and pibrentasvir.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You should not stop using glecaprevir and pibrentasvir suddenly. Stopping suddenly could make your condition harder to treat with hepatitis C antiviral medicine.
Use all hepatitis C medications as directed and read all medication guides you receive. Do not change your dose or stop using a medicine without your doctor's advice. Every person with hepatitis C should remain under the care of a doctor.
If you've ever had hepatitis B, this virus may become active or get worse in the months after you stop using glecaprevir and pibrentasvir. You may need frequent liver function tests while using this medicine and for several months after your last dose.
Store this medicine in the original container at room temperature away from moisture and heat.
Use the medicine as soon as you can, but skip the missed dose if you are more than 18 hours late for the dose. Do not use two doses at one time.
Glecaprevir And Pibrentasvir side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
In rare cases, glecaprevir and pibrentasvir may cause serious liver injury. Tell your doctor right away if you have symptoms such as:
- right-sided upper stomach pain;
- nausea, vomiting, loss of appetite;
- confusion, tiredness, feeling light-headed;
- easy bruising or bleeding, vomiting blood;
- diarrhea, black or bloody stools;
- dark urine; or
- yellowing of your skin or eyes.
Common side effects may include:
- headache; or
- tiredness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Glecaprevir And Pibrentasvir?
Using this medicine will not prevent your disease from spreading. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HCV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.