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Home > Drugs > Malignancy photosensitizers > Gleolan
Malignancy photosensitizers

Gleolan

https://themeditary.com/drug/gleolan-1913.html
Medically Reviewed by Glamora Samuels, MD TheMediTary.Com | Reviewed: Jul 13, 2023  Additional Content by TheMediTary.Com

Generic name: aminolevulinic acid (oral) [ a-mee-noh-lev-yoo-lin-ik-as-id ]

Drug class: Malignancy photosensitizers

Dosage form: powder, for oral solution

Availability: Prescription only

Pregnancy & Lactation: Risk data not available

Brand names: Aminolevulinic acid

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Gleolan?

Gleolan is given before surgery to remove a glioma (a type of brain or spinal cord tumor).

Taking Gleolan causes a certain substance to build up within your tumor tissue. This allows the tissue to be seen more clearly through a special light scope that is used during surgery to remove the tumor.

Gleolan may also be used for purposes not listed in this medication guide.

Warnings

For 48 hours after taking Gleolan, you will need to protect your skin from light, both sunlight and bright indoor light.

How should I use Gleolan

Gleolan is usually given about 3 hours before surgery. A healthcare provider will prepare and give you this medicine.

For 48 hours after taking Gleolan, you will need to protect your skin from bright light. Avoid exposure to both sunlight and bright indoor light. Wear protective clothing and a wide-brimmed hat when you are outdoors. If you feel stinging or burning of the treated skin, reduce your exposure to light.

Detailed Gleolan dosage information
Gleolan Dosage information (more detail)

Before Taking

You should not use Gleolan if you are allergic to Gleolan or porphyrins, or if you have:

  • porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

Tell your doctor if you have ever had liver or kidney disease.

Tell your doctor if you are pregnant.

Do not breastfeed within 24 hours after using Gleolan. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.

What happens if I miss a dose?

Gleolan is used as a single dose and does not have a daily dosing schedule.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid while using Gleolan?

Avoid exposure to sunlight or bright indoor light for 48 hours after taking Gleolan. Wear a hat and clothing that covers your skin.

Gleolan side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Your caregivers will watch you closely to make sure you do not have an allergic reaction, and to treat a reaction if it does occur.

Many side effects can occur up to 6 weeks after you took Gleolan. Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • skin redness or swelling, raised red areas;

  • skin rash, itching, or blistering;

  • a seizure;

  • chills; or

  • trouble speaking or understanding what is said to you.

Common side effects of Gleolan may include:

  • nausea, vomiting, diarrhea; or

  • abnormal liver function tests (for up to 6 weeks after taking Gleolan).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Gleolan Side Effects

What other drugs will affect Gleolan?

Tell your doctor about all your other medicines. Certain medicines also can make you more sensitive to bright light and should be avoided within 24 hours before or after you take Gleolan. This includes:

  • St. John's wort;

  • an antifungal medicine;

  • an antibiotic or sulfa medicine;

  • a diuretic or "water pill";

  • topical medicine containing Gleolan;

  • antipsychotic medicine; or

  • an oral diabetes medicine.

This list is not complete. Other drugs may affect Gleolan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

More about Gleolan (Aminolevulinic acid (oral) [ a-mee-noh-lev-yoo-lin-ik-as-id ])

Dosage information
Gleolan Side Effects
Gleolan Prescribing Information
Drug images
Side effects
Drug class: Malignancy photosensitizers

Related treatment guides

Diagnosis and Investigation
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions
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