Pregnancy & Lactation: Risk data not available
What is Glofitamab?
Glofitamab is used to treat certain types of lymphoma in adults whose cancer has returned or did not respond to another treatment and who have received at least two previous cancer treatments.
Glofitamab may also be used for purposes not listed in this medication guide.
Tell your doctor if you have:
- an active or chronic infection; or
- kidney disease.
May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use effective birth control while using glofitamab and for at least 1 month after your last dose. Tell your doctor right away if you are pregnant or plan to become pregnant.
Do not breastfeed while using this medicine, and for at least 1 month after your last dose.
How should I use Glofitamab
Use Glofitamab (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Read the Patient Wallet Card about serious side effects and learn what symptoms to watch for. Keep the card with you at all times.
Glofitamab is given as an infusion into a vein. A healthcare provider will give you this injection.
Glofitamab is given in a 21-day treatment cycle. You will receive an injection only on certain days of this cycle.
This medicine is given slowly, and the infusion can take up to 8 hours to complete.
You may be given other medications to help prevent serious side effects or allergic reaction. Keep taking these medicines for as long as your doctor has prescribed.
Your healthcare provider will check for cytokine Release Syndrome (CRS) while you are being treated and may treat you in a hospital if you develop signs and symptoms of CRS.
You will need frequent medical tests, and your next dose may be delayed based on the results.
Call your doctor for instructions if you miss an appointment for your glofitamab injection.
Glofitamab side effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.
Call your doctor at once if you have:
- signs and symptoms of nervous system disorders--numbness, tingling or weakness of your hands or feet, sleepiness, dizziness, headache, memory problems, confusion, or disorientation, trouble speaking or understanding what is said to you, trouble concentrating, memory problems, tremors or shaking;
- signs or symptoms of tumor related problems--chest pain, cough, tender or swollen lymph nodes, pain or swelling at the site of the tumor; or
- signs of infection--fever, chills, sore throat, weakness, chest pain, cough, wheezing, trouble breathing.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- abnormal lab results;
- muscle or bone pain;
- chills, shaking;
- fast or irregular heartbeat;
- dizziness, feeling light-headed; or
- fever with shortness of breath, trouble breathing.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Glofitamab?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.