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Home > Drugs > Miscellaneous antifungals > Griseofulvin
Miscellaneous antifungals

Griseofulvin

https://themeditary.com/drug/griseofulvin-351.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Jul 10, 2023  Additional Content by TheMediTary.Com

Generic name: griseofulvin [ gris-ee-oh-ful-vin ]

Drug class: Miscellaneous antifungals

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Contents
Uses Warnings Before Taking Dosage Side effects Interactions
  • Griseofulvin (Griseofulvin [ gris-ee-oh-ful-vin ])-WARRICK 1624 1624-330 mg-White-Oval Griseofulvin 330 mg (WARRICK 1624 1624)
  • Griseofulvin (Griseofulvin [ gris-ee-oh-ful-vin ])-WARRICK 1621-250 mg-White-Round Griseofulvin 250 mg (WARRICK 1621)
  • Griseofulvin (Griseofulvin [ gris-ee-oh-ful-vin ])-I26-500 mg-White-Round Griseofulvin 500 mg (I26)
  • Griseofulvin (Griseofulvin [ gris-ee-oh-ful-vin ])-C P 295-125 mg-White-Oval Griseofulvin 125 mg (C P 295)
  • View all images

What is Griseofulvin?

Griseofulvin is an antifungal medicine that is used to treat infections such as ringworm, athlete's foot, jock itch, and fungal infections of the scalp, fingernails, or toenails.

Griseofulvin may also be used for purposes not listed in this medication guide.

Warnings

You should not use griseofulvin if you have porphyria or liver failure.

Taking griseofulvin during the first 3 months of pregnancy may harm the unborn baby.

How should I take Griseofulvin

Griseofulvin comes as a tablet, capsule, and liquid to take by mouth. It is usually taken once a day or can be taken two to four times a day. Although your symptoms may get better in a few days, you will have to take griseofulvin for a long time before the infection is completely gone. It is usually taken for 2 to 4 weeks for skin infections, 4 to 6 weeks for hair and scalp infections, 4 to 8 weeks for foot infections, 3 to 4 months for fingernail infections, and at least 6 months for toenail infections. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take griseofulvin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Continue to take griseofulvin even if you feel well. Do not stop taking griseofulvin without talking to your doctor.

Dosing information

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose as your infection improves. Use the medicine exactly as directed.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Tell your doctor if you cannot swallow a tablet whole. You may be able to crush the tablet and sprinkle the medicine into a spoonful of applesauce. Swallow the mixture right away without chewing. Do not save it for later use.

While treating a fungal skin or nail infection, keep the skin areas as clean and dry as possible.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication.

Griseofulvin will not treat a bacterial or viral infection such as the flu or a common cold. Griseofulvin also will not treat certain types of fungal infections, including yeast infections.

It may take up several weeks before your symptoms improve. Nail infections can take several months to clear completely.

Call your doctor if your symptoms do not improve, or if they get worse.

If you use this medicine long-term, you may need frequent medical tests.

Store at room temperature away from moisture, heat, and light.

Detailed Griseofulvin dosage information
Griseofulvin Dosage information (more detail)

Before Taking

You should not use griseofulvin if you are allergic to it, or if you have:

  • liver failure;

  • porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system); or

  • if you are pregnant or may become pregnant.

Tell your doctor if you have ever had:

  • liver disease;

  • lupus; or

  • an allergy to penicillin.

Taking griseofulvin during the first 3 months of pregnancy may cause birth defects. Do not take griseofulvin if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine.

Griseofulvin can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy.

You should not breastfeed while using griseofulvin.

Griseofulvin is not approved for use by anyone younger than 2 years old.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Keep the liquid away from light. Do not freeze.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

What should I avoid while using Griseofulvin?

Avoid covering affected skin areas with tight-fitting, synthetic clothing (such as nylon or polyester clothing, or plastic pants) that does not allow air to circulate to your skin. If you are treating athlete's foot, wear clean cotton socks and sandals or shoes that allow for air circulation. Keep your feet as dry as possible.

Griseofulvin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Drinking alcohol with griseofulvin can cause side effects.

Griseofulvin side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Griseofulvin may cause serious side effects. Call your doctor at once if you have:

  • numbness, tingling, or burning pain in your hands or feet;

  • confusion, trouble with daily activities;

  • fever, chills, flu symptoms, white patches or sores inside your mouth or throat;

  • liver problems--loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes);

  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath, foamy urine;

  • lupus-like symptoms--muscle or joint pain, flu symptoms, chest pain, and a rash or patchy skin color that worsens in sunlight; or

  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects of griseofulvin may include:

  • nausea, vomiting, upset stomach, diarrhea;

  • headache, tiredness;

  • rash;

  • sleep problems (insomnia); or

  • dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Griseofulvin Side Effects

What other drugs will affect Griseofulvin?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect griseofulvin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to griseofulvin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. If you still have symptoms of infection after you finish the griseofulvin, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

What to Expect

Your symptoms may begin to improve after a few days, but fungal infections usually take a while to completely clear.

It typically takes two to four weeks for skin infections, three to four months for fingernail infections, and at least six months for toenail infections to heal.

Continue to take this medicine as long as your doctor tells you to do so.

Let your provider know if you experience any severe or unusual side effects.

Additional Dosage Information

Your dosage of griseofulvin will depend on your medical condition, the formulation you use, your age, your weight, and other factors.

Follow the instructions on your prescription label carefully when using this medicine.

Secondary Uses

Griseofulvin may be used to treat other types of fungal infections that aren’t listed in this medical guide.

More about Griseofulvin (Griseofulvin [ gris-ee-oh-ful-vin ])

Dosage information
Griseofulvin Side Effects
During pregnancy
Drug images
Side effects
Drug class: Miscellaneous antifungals

Patient resources

Advanced Reading: Griseofulvin (Oral)
Griseofulvin Microsize Tablets
Griseofulvin Ultramicrosize Tablets
Griseofulvin Microsize Oral Suspension

Related treatment guides

Onychomycosis, Toenail
Onychomycosis, Fingernail
Tinea Barbae
Dermatophytosis
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