Generic name: Tarlatamab
Pregnancy & Lactation: Risk data not available
What is Imdelltra?
Tarlatamab is used to treat non-small cell lung cancer in adults who are no longer responding to platinum-based chemotherapy.
Tarlatamab is used when the cancer has progressed or has spread to other parts of the body (metastatic).
Tarlatamab may also be used for purposes not listed in this medication guide.
Warnings
Tell your doctor if you have or have ever had:
- an allergic reaction to this medicine; or
- an active or chronic infection.
May harm an unborn baby. Use effective birth control while using tarlatamab and for at least 2 months after your last dose. Tell your doctor if you are pregnant or plan to become pregnant.
You may need to have a negative pregnancy test before starting this treatment.
Do not breastfeed while using this medicine, and for at least 2 months after your last dose.
How should I use Imdelltra
Use Imdelltra (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Tarlatamab is given as an infusion into a vein. A healthcare provider will give you this injection.
Tarlatamab is usually given once every 2 week in a 28-day treatment cycle. You will receive an injection only on certain days of this cycle.
This medicine must be given slowly over 60 minutes.
You may be given other medications to treat or prevent certain side effects.
Your blood will be tested before and during treatment with tarlatamab. You will need frequent blood tests to check your liver function.
Call your doctor for instructions if you miss an appointment for your tarlatamab injection.
Imdelltra side effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;
- signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding; or
- symptoms of liver failure--diarrhea, loss of appetite, pain or swelling in your stomach, swelling in your legs, easy bleeding, drowsiness, confusion, or jaundice (yellowing of the skin or eyes).
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- abnormal lab results;
- constipation, nausea;
- metallic taste in your mouth;
- muscle or bone pain;
- tiredness;
- fever; or
- loss of appetite.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Imdelltra?
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness, drowsiness, confusion, tremors, or any other symptoms that impair consciousness can cause falls, accidents, or severe injuries.