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Home > Drugs > Aldosterone receptor antagonists > Inspra
Aldosterone receptor antagonists

Inspra

https://themeditary.com/drug/inspra-2066.html
Medically Reviewed by Glamora Samuels, MD TheMediTary.Com | Reviewed: Jul 13, 2023  Additional Content by TheMediTary.Com

Generic name: eplerenone [ ep-ler-e-none ]

Drug class: Aldosterone receptor antagonists, Potassium-sparing diuretics

Dosage form: tablet, film coated

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Eplerenone

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Inspra?

Inspra is used to lower the risk of death from heart failure after a heart attack.

Inspra is also used to treat high blood pressure (hypertension).

Inspra may also be used for purposes not listed in this medication guide.

Warnings

You may not be able to take Inspra if you have severe kidney disease, high potassium levels in your blood, or type 2 diabetes with increased levels of albumin (a protein) in your urine.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

How should I use Inspra

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Inspra may be taken with or without food.

You may need blood tests, and your blood pressure will need to be checked often.

If you have high blood pressure, keep using Inspra even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Store at room temperature away from moisture and heat.

Detailed Inspra dosage information
Inspra Dosage information (more detail)

Before Taking

You may not be able to take this medicine if you are allergic to Inspra, or if you have:

  • high potassium levels in your blood (hyperkalemia);

  • severe kidney disease; or

  • type 2 diabetes with increased levels of albumin (a protein) in your urine.

Some medicines can cause unwanted or dangerous effects when used with Inspra. Your doctor may change your treatment plan if you also use:

  • nefazodone;

  • a potassium supplement;

  • an antibiotic--clarithromycin, telithromycin;

  • antifungal medicine--itraconazole, ketoconazole;

  • a diuretic or "water pill"--amiloride, spironolactone, triamterene; or

  • antiviral medicine to treat HIV/AIDS--indinavir, nelfinavir, ritonavir, saquinavir.

Tell your doctor if you have ever had:

  • kidney disease;

  • diabetes;

  • liver disease;

  • high cholesterol or triglycerides; or

  • if you take other heart or blood pressure medications.

Tell your doctor if you are pregnant or breastfeeding.

It is not known whether Inspra will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). Heart failure can get worse during pregnancy and may cause complications such as premature birth. The benefit of treating hypertension or heart failure may outweigh any risks to the baby.

This medicine may affect fertility (ability to have children) in men.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Inspra?

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Inspra side effects

Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Inspra may cause serious side effects. Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • diarrhea, vomiting;

  • little or no urination;

  • fast or irregular heartbeats;

  • trouble breathing;

  • swelling in your feet or lower legs; or

  • high potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects of Inspra may include:

  • high potassium;

  • headache; or

  • dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Inspra Side Effects

What other drugs will affect Inspra?

Tell your doctor about all your current medicines. Many drugs can affect Inspra, especially:

  • lithium;

  • heart or blood pressure medicine--amiodarone, benazepril, diltiazem, dronedarone, enalapril, lidocaine, lisinopril, olmesartan, valsartan, verapamil, and others; or;

  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete and many other drugs may affect Inspra. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

More about Inspra (Eplerenone [ ep-ler-e-none ])

Dosage information
Inspra Side Effects
During pregnancy
Inspra Prescribing Information
Drug images
Side effects
Drug class: Aldosterone receptor antagonists

Related treatment guides

High Blood Pressure
Heart Failure
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Uses Warnings Before Taking Dosage Side effects Interactions
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