In the US, Isotretinoin (isotretinoin systemic) is a member of the following drug classes: miscellaneous antineoplastics, miscellaneous uncategorized agents and is used to treat Acne, Acute Nonlymphocytic Leukemia, Granuloma Annulare, Melanoma - Metastatic, Pityriasis rubra pilaris and Rosacea.

US matches:

• Isotretinoin (Eqv-Absorica)
• Isotretinoin
• ISOtretinoin (Systemic)
• Isotretinoin Capsules

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

D10AD04,D10BA01

CAS registry number (Chemical Abstracts Service)

0004759-48-2

Chemical Formula

C20-H28-O2

Molecular Weight

300

Therapeutic Categories

Antiacne agent

Retinoid

Chemical Name

Retinoic acid, 13-cis-

Foreign Names

• Isotretinoinum (Latin)
• Isotretinoin (German)
• Isotrétinoïne (French)
• Isotretinoina (Spanish)

Generic Names

• Isotretinoin (OS: USAN, BAN)
• Isotretinoina (OS: DCIT)
• Isotrétinoïne (OS: DCF)
• 13-cis-retinoic acid (IS)
• Ro 4-3780 (IS)
• Isotretinoin (PH: BP 2018, Ph. Eur. 9.5, USP 41)
• Isotrétinoïne (PH: Ph. Eur. 9)
• Isotretinoinum (PH: Ph. Eur. 9.5)

Brand Names

• Aaiso
  Iscon Life Sciences, India
• Absorica
  Ranbaxy, United States
• Accuran
  Nexus Medicals, Greece
• Accure
  Dermagen, Pakistan
• Accutane Roche
  Hoffmann-La Roche, Canada
• Accutin
  Sandoz, Denmark
• Acne Free
  Amoun, Egypt
• Acne Free 0.025%
  Amoun, Egypt
• Acne Free 0.05%
  Amoun, Egypt
• Acnecur
  Catedral, Paraguay
• Acnecutan
  Jadran Galenski, Russian Federation
• Acnegen 10 mg
  Biogen, Turkey
• Acnegen 20 mg
  Biogen, Turkey
• Acnemin
  Vinas, Spain
• Acneone
  Genesis, India
• Acneral
  Laboratorio Chile, Chile
• Acneral MD
  Laboratorio Chile, Chile
• Acnestar
  Mankind, India
• Acneta
  Taha Pharma, Tunisia
• Acnetane
  Al Pharm, South Africa
• Acnetin A 0.025%
  Sigma, Egypt
• Acnetin A 0.05%
  Sigma, Egypt
• Acnétrait 10 mg
  Arrow, France
• Acnétrait 20 mg
  Arrow, France
• Acnétrait 40 mg
  Arrow, France
• Acnétrait 5 mg
  Arrow, France
• Acnetrex 10
  Mega Lifesciences, Philippines
• Acnetrex 20
  Mega Lifesciences, Philippines
• Acnex-20
  Unichem, India
• Acnezac
  Olcare Laboratories, India
• Acnisil
  Assure Aplomb, India
• Acnizo
  Zenon, India
• Acno
  Ajanta, India; Paramount, Pakistan
• Acnogen
  Genepharm, Greece
• Acnotin
  Bago, Peru; Bagó, Ecuador; Laboratorio Bago, Chile; Mega Lifesciences, Hong Kong; Mega Lifesciences, Myanmar; Mega Lifesciences, Singapore; Mega Lifesciences, Thailand
• Acnotren
  Pharmathen, Lebanon
• A-Cnotren
  Pharmathen, Greece; Pharmathen, Thailand
• Acnova
  Germed Farmaceutica, Brazil
• Acretin 0.025%
  jamjom, Egypt
• Acretin 0.05%
  jamjom, Egypt
• Actaven
  Actavis Group, Poland
• Acugen
  Olive Healthcare, Philippines
• Acutret
  IPCA, India
• Acutrex
  Medica Korea, Philippines
• Adclin
  Sigman, India
• Ai Si Jie
  Dazhong Pharmaceutical, China
• Aisoskin
  Fidia Farmaceutici, Italy
• Aknal
  Dong-A, South Korea
• Aknenormin
  Almirall Hermal, Czech Republic; Almirall Hermal, Poland; Hermal, Slovakia
• Aknenormin 10mg
  Almirall Hermal, Germany; Almirall Hermal, Hungary
• Aknenormin 20mg
  Almirall Hermal, Germany; Almirall Hermal, Hungary
• Aknetrent 10 mg
  Recordati, Turkey
• Aknetrent 20 mg
  Recordati, Turkey
• Amnesteem
  Mylan, United States
• Apex-Isotretinoin
  Camox, South Africa
• APO-Isotretinoin
  Apotex, Australia
• Atlacne
  Atlas Farmc., Argentina
• Atretin Lafrancol
  Abbott, Colombia
• Axotret
  Axxon, Poland
• Casius
  Swiss & North, Ecuador
• Cecnoin
  Eurofarma, Brazil
• Ciscutan 10 mg
  Pelpharma, Austria
• Ciscutan 20 mg
  Pelpharma, Austria
• Ciscutan 30 mg
  Pelpharma, Austria
• Ciscutan 40 mg
  Pelpharma, Austria
• Ciscutan 5 mg
  Pelpharma, Austria
• Claravis
  Teva, United States
• Clarus
  Mylan Pharmaceuticals, Canada
• Contracne
  Laboratoires Bailleul, Malta
• Contracné
  Bailleul, France
• Cosmin
  Saffron, Pakistan
• Curacne
  Pierre Fabre, Lebanon; Pierre Fabre, Tunisia; Pierre Fabre, Vietnam; Pierre Fabre Dermatologie, France; Pierre Fabre Dermatologie, Poland
• Curacné
  Pierre Fabre, Czech Republic; Pierre Fabre Medicament, Slovakia
• Curacne Gé
  Pierre Fabre, Tunisia
• Curakne 10mg
  Pierre Fabre, Switzerland
• Curakne 20mg
  Pierre Fabre, Switzerland
• Curakne 40mg
  Pierre Fabre, Switzerland
• Curakne 5mg
  Pierre Fabre, Switzerland
• Curatane 10mg
  Douglas, Israel
• Curatane 20mg
  Douglas, Israel
• Curatane 5mg
  Douglas, Israel
• Cuticilin
  Vivax, Venezuela
• Decutan
  Actavis, Tunisia; Actavis Group, Iceland; Actavis Group, Malta
• Dercutane
  Cantabria, Spain
• Dermalona
  Bagó, Colombia
• Dermatane
  Eris Pharmaceutical, Australia
• Effederm
  c. erba, Egypt
• Epuris
  Cipher Pharmaceuticals, Canada
• Erynocin [+ Erythromycin]
  Sante, Pakistan
• Esotek [+ Erythromycin]
  Zam Zam, Pakistan
• Etrexin [+ Erythromycin]
  Vem Ilaç, Turkey
• Eudyna 0.05%
  Abbott, Egypt
• Faclynel
  Italmex, Mexico
• Flexresan
  Centrum, Spain; Raymos, Argentina
• Hyndriax
  Roemmers, Peru
• Inerta 10 mg
  Actavis, Hungary
• Inerta 20 mg
  Actavis, Hungary
• Inflader
  Royal Pharma, Chile
• I-Ret
  Adcock Ingram, India
• Isac
  Systopic, India
• Isdiben
  Isdin, Spain
• Isoacne
  Pierre Fabre Iberica, Spain
• Isoacne [+ Erythromycin]
  Neophar, Pakistan
• Isobest
  Glenmark, India
• Isocheck
  Pharmacheck, Peru
• Isocural
  Pierre Fabre Sante, Belgium
• Isocutan
  Raffo, Argentina
• Isoderm
  Candid, Pakistan; Dermapharm, Germany; Sun-Farm, Poland
• Isoface
  Genome, Pakistan; Interpharm, Ecuador; Procaps, Colombia; Recalcine, Paraguay; Unimed, Peru; Vivax, Venezuela
• IsoGalen
  Galenpharma, Germany
• Isolve
  Suiphar, Dominican Republic
• Isoriac
  Pierre Fabre Italia, Italy
• Isosupra
  Smb Technology, Lebanon
• Isosupra Lidose
  Laboratoires SMB, Belgium
• Isotane
  Micro Gratia, India; Mylan, New Zealand
• Isotina
  Taiguk, South Korea
• Isotinon
  Hanmi, South Korea
• Isotrat (C2)
  Nova Química Farmacêutica, Brazil
• Isotren
  Korean Drug, South Korea
• Isotret-HEXAL
  Hexal, Germany
• Isotretinoin
  Alliance Pharmaceuticals, United Kingdom; Amneal Pharmaceuticals, United States; Ennogen Healthcare, United Kingdom; Ranbaxy, United Kingdom
• Isotretinoin Actavis
  Actavis, Sweden; Actavis, Slovakia
• Isotretinoin AN
  Amneal Pharma, Australia
• Isotretinoin Jenson
  Generics, Poland
• Isotretinoin NeoFarma
  NeoFarma, Malta
• Isotretinoin Orifarm
  Orifarm Generics, Norway; Orifarm Generics, Sweden
• Isotretinoin Orion
  Orion Pharma, Denmark; Orion Pharma, Finland
• Isotretinoin Ranbaxy
  Ranbaxy, Egypt
• Isotretinoin Ratiopharm
  Ratiopharm GmbH, Iceland
• Isotretinoin Sandoz
  Sandoz, Lithuania
• Isotretinoin SCP
  Southern Cross Pharma, Australia
• Isotretinoin Terapia
  Terapia, Romania
• Isotretinoin Teva
  Teva, Denmark
• Isotretinoína Aurovitas
  Aurovitas, Portugal
• Isotretinoina Difa Cooper
  Difa Cooper, Italy
• Isotretinoina Dutriec
  Dutriec, Paraguay
• Isotretinoina EG
  EG, Italy
• Isotretinoina Elifarma 20mg
  Elifarma, Paraguay
• Isotretinoína EMS
  EMS, Brazil
• Isotretinoína Gen.Germed
  Genéric.Germed, Brazil
• Isotretinoína Generis
  Generis, Portugal
• Isotretinoina Idifarma
  Ranbaxy, Spain
• Isotretinoína Nova Quimica
  Nova Química Farmacêutica, Brazil
• Isotretinoína Orotrex
  Medinfar, Portugal
• Isotretinoina Pharma Arte
  Pharma Arte, Paraguay
• Isotretinoína Pierre Fabre
  Pierre Fabre, Portugal
• Isotretinoína Ranbaxy
  Ranbaxy, Brazil
• Isotretinoina Servimedic
  Servimedic, Uruguay
• Isotretinoina Stiefel
  Stiefel, Italy
• Isotretinoina Sun
  SUN Pharmaceuticals Italia, Italy
• Isotretinoína Valeant
  Valeant, Brazil
• Isotretinoïne Aurobindo
  Aurobindo, Netherlands
• Isotretinoine EG
  Eurogenerics, Belgium
• Isotretinoïne Mylan
  Mylan, Netherlands
• Isotretinoïne Sandoz
  Sandoz, Netherlands
• Isotretinoïne SUN
  Sun Pharma, Netherlands
• Isotretinoin-Humanity
  XL, Georgia
• Isotretinoin-Mepha 10mg
  Mepha Pharma, Switzerland
• Isotretinoin-Mepha 20mg
  Mepha Pharma, Switzerland
• Isotretinoin-Mepha 40mg
  Mepha Pharma, Switzerland
• Isotretinoin-PS
  Pfizer, Australia
• Isotretinoin-ratiopharm
  ratiopharm, Germany
• Isotretinoin-Teva 10 mg
  Teva, Hungary
• Isotretinoin-Teva 20 mg
  Teva, Hungary
• Isotrex
  GlaxoSmithKline, Germany; GlaxoSmithKline, Singapore; Stiefel, China; Stiefel, Germany; Stiefel, Spain; Stiefel, United Kingdom; Stiefel, Hong Kong; Stiefel, Ireland; Stiefel, Italy; Stiefel, Mexico; Stiefel, Philippines; Stiefel, Pakistan; Stiefel, Portugal; Stiefel, Taiwan; Stiefel, South Africa; Stiefel Laboratories Polska Sp. z.o.o., Poland; Unimed & Unihealth, Bangladesh
• Isotrex 0.05%
  GlaxoSmithKline, Germany; Laboratorios Stiefel de Chile y Cia., Chile; Stiefel, Egypt
• Isotrex 0.1%
  GlaxoSmithKline, Germany
• Isotrex Eritromicina [+ Erythromycin]
  Stiefel, Spain
• Isotrexin [+ Erythromycin]
  GlaxoSmithKline, Cyprus; GlaxoSmithKline, Germany; GlaxoSmithKline, Romania; GlaxoSmithKline, Singapore; GlaxoSmithKline, Turkey; Stiefel, Germany; Stiefel, United Kingdom; Stiefel, Italy; Stiefel, Lebanon; Stiefel, Portugal; Stiefel, Taiwan; Stiefel Laboratories Polska Sp. z.o.o., Poland
• Isotroin
  Cipla, India; Cipla, Lebanon; Iasis Pharma, Greece; IASIS Pharmaceuticals Hellas, Cyprus; Servimedic, Uruguay
• Izotek
  PharmaSwiss, Poland
• Izotziaja
  Ziaja, Poland
• Lisacne
  ABL, Ecuador; Laboratorios Andromaco, Chile
• Lissage 10
  LIBRA, Uruguay
• Lissage 20
  LIBRA, Uruguay
• Locatret 0.1%
  GNP, Egypt
• Mayesta
  Bama-Geve, Spain
• Munderm [+ Erythromycin]
  Helba, Turkey; Merkez, Georgia
• Myorisan
  VersaPharm, United States
• Neotrex
  Serral, Mexico
• Netlook
  Andalous, Egypt
• Nimegen
  Medica Korea, South Korea; Medica Korea, Malaysia; Medica Korea, Singapore
• Novacne
  Novofarm, Greece
• Novacne 0.05%
  Novofarm, Greece
• Oralne
  Laboratorio Deutsche Pharma, Chile
• Oraret
  Palsons, India
• Oratane
  Arrow Pharmaceuticals, Australia; Darier, Mexico; Douglas, Hong Kong; Douglas, New Zealand; Douglas, Singapore; Pharmaplan, South Africa
• Piplex
  Mediderm, Chile; Mediderm, Peru
• Procuta
  Expanscience, France
• Reducar
  G.A. Pharmaceuticals, Hong Kong; Gap, Greece
• Retin A 0.025%
  Sofeco, Egypt
• Retin A 0.05%
  Janssen-Cilag, Egypt
• Retmicin [+ Erythromycin]
  Verisfield, Greece
• Roaccutan
  Investi, Argentina; Roche, Colombia; Roche, Ecuador; Roche, Italy; Roche, Peru; Roche, Paraguay; Roche, Venezuela; Roche Uruguay, Uruguay; Uhlmann-Eyraud Pharma, Switzerland
• Roaccutan 10 mg
  Roche, Hungary
• Roaccutan 10mg
  Roche Pharma Schweiz, Switzerland
• Roaccutan 20 mg
  Roche, Hungary
• Roaccutan 20mg
  Roche Pharma Schweiz, Switzerland
• Roaccutane
  F. Hoffmann-La Roche, Macedonia; Hoffmann La Roche, Kuwait; Roche, Bosnia & Herzegowina; Roche, Bangladesh; Roche, Belgium; Roche, Bulgaria; Roche, Estonia; Roche, Egypt; Roche, Hong Kong; Roche, Croatia (Hrvatska); Roche, Ireland; Roche, Lithuania; Roche, Moldova; Roche, Philippines; Roche, Romania; Roche, Thailand; Roche, Turkey; Roche, Taiwan; Roche, South Africa; Roche Products, Australia; Roche Products, United Kingdom; Rp Scherer, Lebanon
• Roaccutane 0.05%
  SERP, France
• Roaccutane 10mg
  Roche, Israel; Roche, Luxembourg; Roche, Oman
• Roaccutane 20mg
  Roche, Israel; Roche, Luxembourg; Roche, Oman
• Roaccutane Roche
  Hoffmann-La Roche Ltd, Latvia
• Roacnetan
  Productos Roche, Chile
• Roacta
  MacroPhar, Thailand
• Roacutan
  Roche, Brazil
• Rocta
  Southern Cross Pharma, Australia
• Rotaxin
  Hadjiconstantinou Bros, Cyprus
• Rotren
  Sapiens Pharmaceuticals, Cyprus
• Sotret
  Daiichi, Thailand; Elimera, Colombia; Terapia, Romania
• Sotret 10mg
  Ranbaxy, Oman
• Sotret 20 mg
  Ranbaxy, Oman; Terapia, Hungary
• Stiefotrex
  GlaxoSmithKline A.B.E.E., Greece
• Stiefotrex 0.05%
  GlaxoSmithKline A.B.E.E., Greece
• Tai Er Si
  Sine Pharmaceutical, China
• Teweisi
  Donghai Pharmaceutical, China
• Tretin
  Target Pharma, Greece
• Tretinac 10mg
  Recordati AG, Switzerland
• Tretinac 20mg
  Recordati AG, Switzerland
• Tretinac 5mg
  Recordati AG, Switzerland
• Tretinex
  Abbott, Colombia; Medana Pharma, Poland
• Tufacne
  AHPL, India
• Xeractan 10mg
  Jazeera Pharmaceutical Industry JPI, Oman
• Xeractan 20mg
  Jazeera Pharmaceutical Industry JPI, Oman
• Zenatane
  Dr. Reddy's, United States
• Zerocutan
  Joongwae Shinyak, South Korea
• Zoretanin
  Actavis, Turkey

Glossary

Further information on drug naming conventions: International Nonproprietary Names.