Note: In some countries, this medicine may only be approved for veterinary use.

In the US, Itraconazole (itraconazole systemic) is a member of the drug class azole antifungals and is used to treat Aspergillosis - Aspergilloma, Aspergillosis - Invasive, Blastomycosis, Candida Urinary Tract Infection, Candidemia, Coccidioidomycosis, Cryptococcal Meningitis - Immunosuppressed Host, Cryptococcosis, Dermatophytosis, Esophageal Candidiasis, Febrile Neutropenia, Fungal Infection Prophylaxis, Histoplasmosis, Microsporidiosis, Onychomycosis - Fingernail, Onychomycosis - Toenail, Oral Thrush, Paracoccidioidomycosis, Sporotrichosis, Systemic Fungal Infection, Tinea Capitis, Tinea Versicolor and Vaginal Yeast Infection.

US matches:

• Itraconazole
• Itraconazole Capsules (Sporanox)
• Itraconazole Capsules (Tolsura)
• Itraconazole Oral Solution
• Itraconazole Tablets

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

J02AC02

CAS registry number (Chemical Abstracts Service)

0084625-61-6

Chemical Formula

C35-H38-Cl2-N8-O4

Molecular Weight

706

Therapeutic Categories

Antifungal agent

Triazole derivative

Chemical Names

(±)-1-sec-Butyl-4-[p-[4-(p-[[(2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmetyl)-1,3-dioxolan-4-yl]metoxy]phenyl)-1-piperazinyl]phenyl]-delta²-1,2,4-triazolin-5-one (WHO)

(±)-1-sec-Butyl-4-{4-[4-(4-{[(cis-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmetyl)-1,3-dioxolan-4-yl]metoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1,2,4-triazol-5-on (IUPAC)

Foreign Names

• Itraconazolum (Latin)
• Itraconazol (German)
• Itraconazole (French)
• Itraconazol (Spanish)

Generic Names

• Itraconazole (OS: JAN, DCF, USAN, BAN)
• R 51211 (Janssen) (IS)
• Itraconazol (PH: Ph. Eur. 9)
• Itraconazole (PH: BP 2018, JP XVII, Ph. Eur. 9, USP 41)
• Itraconazolum (PH: Ph. Eur. 9)

Brand Names

• Adco-Sporozole
  Al Pharm, South Africa
• Afderm
  Anglo French, India
• Albisec [+ Secnidazole]
  Procaps, Colombia; Unimed, Peru
• Allitra
  Allure, India
• APO-Itraconazole
  Apotex, Australia
• Aranox
  APT Pharma, Hong Kong
• Arozole
  Acapi, Egypt
• Assosept-S
  S.J.A., Greece
• Biospore
  Biosciences, India
• Brovicton
  Bros, Greece
• Canadiol
  Laboratorios Dr. Esteve, Spain
• Canditral
  Glenmark, India; Glenmark, Peru; Glenmark, Philippines; Glenmark, Singapore; Glenmark, Thailand; Glenmark Pharmaceuticals, Vietnam
• Chme
  Wecam, Taiwan
• Cladosol
  STADA, Estonia; STADA, Lithuania; STADA, Latvia
• Conamed
  Bajamed, Mexico
• Deratil
  Help, Greece
• Derusil
  Loeffler, Mexico
• Efectra
  Chong Kun Dang, South Korea
• Enitrax
  Procaps, Colombia
• Etrel
  Pharmex, Greece; T.C.Christoforou, Cyprus
• Flunol
  Pharma Q, Cyprus
• Fonginox
  Mediphar, Lebanon
• Forcanox
  Guardian Pharmatama, Indonesia
• Fubizol
  Buffington's, Mexico
• Fungitraxx [veterinary use]
  Albrecht, Germany; Avimedical, Belgium; Avimedical, Estonia; Avimedical, Iceland; Avimedical, Poland; Petlife, United Kingdom
• Fungitraxx 10 mg/ml für Ziervögel For birds [veterinary use]
  Avimedical, Austria
• Fungitraxx 10 mg/ml voor siervogels [veterinary use]
  Avimedical, Netherlands
• Fungitrazol
  Ikapharmindo, Indonesia
• Fungofunal
  Salutas Pharma, Bulgaria
• Fungosin
  Dollder, Venezuela
• Fungospor
  Verisfield, Greece
• Funit
  Nobel, Turkey
• Fuzoltec
  Tecnofarma, Mexico
• Gitrasek [+ Secnidazole]
  Chinoin, Costa Rica; Chinoin, Dominican Republic; Chinoin, Guatemala; Chinoin, Mexico; Chinoin, Nicaragua; Chinoin, Panama
• Hanall Itraconazole
  Hanall Biopharma, South Korea
• Hitrazole
  Joongwae Shinyak, South Korea
• Hongoseril
  Isdin, Spain
• Icomein
  Everest, Taiwan
• Icon
  Ferozsons, Pakistan
• Iconazol
  Shin Poong, South Korea
• Igrazol
  Graha, Indonesia
• Ikonaz
  Farmal, Croatia (Hrvatska)
• Ilpez
  Rafarm, Greece
• Inox
  Hovid, Hong Kong; Hovid, Malaysia; Hovid, Philippines
• Inrozol
  Boderm, Greece
• Ipozumax
  Temapharm, Poland
• Iqcona
  IQFA, Mexico
• Isoflon
  Proel, Greece
• Isox
  Senosiain, Dominican Republic; Senosiain, Guatemala; Senosiain, Honduras; Senosiain, Mexico; Senosiain, Panama; Senosiain, El Salvador
• Itacona
  Korean Drug, South Korea
• Itaspor-Aversi
  Aversi, Georgia
• Itazol
  Shaheen, Pakistan
• Itcona
  Medica Korea, South Korea
• Itodal
  Cormin, Ecuador; Laboratorio Chile, Chile
• Itra
  East West, India; English, Pakistan; MacroPhar, Thailand; Opalia, Tunisia; Square, Bangladesh
• Itrabene
  ratiopharm Arzneimittel, Austria
• Itrabene Dermis
  ratiopharm Arzneimittel, Austria
• Itrabest
  Phoenix E.P, Greece
• Itrac 100
  Cassara, Argentina; D & M Pharma, Chile; Pablo Cassara, Paraguay; Promofarma, Uruguay
• Itrac 200
  Cassara, Argentina
• Itrac 3
  Belupo, Croatia (Hrvatska)
• Itracap
  Alphapharm, Australia; Karmann, Pakistan
• Itracare
  Sandoz, Ecuador
• Itracim
  Acino, Georgia; Acino, Tunisia
• Itracim 100mg
  Acino Pharma, Switzerland
• Itracol HEXAL
  Hexal, Germany
• Itracon
  Cipharma, Uruguay; GNP, Egypt; Kukje, South Korea; Navana, Bangladesh; Reko, Pakistan; Unison, Hong Kong; Unison, Thailand; Unison Laboratories Co Ltd, Myanmar; Vianex, Greece
• Itraconazol
  Kener, Mexico; Medrock, Peru
• Itraconazol - 1 A Pharma
  1 A Pharma, Germany
• Itraconazol AbZ
  AbZ-Pharma, Germany
• Itraconazol Actavis
  Actavis, Lithuania; Actavis, Latvia; Actavis, Portugal; Actavis Baltics Eesti, Estonia; Actavis Group, Malta
• Itraconazol AL
  Aliud Pharma, Germany
• Itraconazol Alter
  Alter, Spain; Alter, Portugal
• Itraconazol Apotex
  Apotex, Belgium
• Itraconazol Arena
  Arena, Romania
• Itraconazol Aristo
  Aristo Pharma, Germany
• Itraconazol Aurobindo
  Aurobindo, Netherlands
• Itraconazol Axapharm 100mg
  Axapharm, Switzerland
• Itraconazol CF
  Centrafarm, Netherlands
• Itraconazol Cinfa
  Cinfa, Spain
• Itraconazol Dermapharm
  Dermapharm, Netherlands
• Itraconazol dura
  Mylan dura, Germany
• Itraconazol EG-100
  Eurogenerics, Luxembourg
• Itraconazol Farmex
  Farmex, Romania
• Itraconazol Fisher
  Dr. Fisher Farma, Netherlands
• Itraconazol Fmndtria
  Farmindustria, Peru
• Itraconazol Fungizol
  Heumann, Bulgaria; Liconsa, Bulgaria
• Itraconazol Generis
  Generis, Portugal
• Itraconazol Genfarma
  Genfarma, Spain
• Itraconazol Germed
  Germed, Portugal
• Itraconazol Helvepharm 100mg
  Helvepharm, Switzerland
• Itraconazol Heumann
  Heumann, Germany
• Itraconazol Ienzimed
  Joint Stock Company Olainfarm, Romania
• Itraconazol Mylan
  Mylan, Spain; Mylan, Netherlands
• Itraconazol Normon
  Normon, Spain
• Itraconazol PCH
  Pharmachemie, Netherlands
• Itraconazol Pharma Arte
  Pharma Arte, Paraguay
• Itraconazol Ramos
  Ramos, Nicaragua
• Itraconazol ratiopharm
  Ratiopharm, Portugal
• Itraconazol Sandoz
  Sandoz, Portugal; Sandoz España, Spain
• Itraconazol Sandoz 100mg
  Sandoz, Austria
• Itraconazol Sandoz eco 100mg
  Sandoz, Switzerland
• Itraconazol Slavia
  Slavia Pharm, Romania
• Itraconazol Spirig 100mg
  Bailleul SA, Switzerland
• Itraconazol Stada
  STADA, Spain
• Itraconazol STADA
  STADA, Netherlands; Stada Arzneimittel, Germany
• Itraconazol Stada 100 mg
  Stada Arzneimittel, Austria
• Itraconazol Tarbis
  Tarbis, Spain
• Itraconazol Tecnigen
  Tecnimede, Spain
• Itraconazol Teva
  Teva Nederland, Netherlands
• Itraconazol Tolife
  ToLife, Portugal
• Itraconazol Tosicina
  Sandoz España, Spain
• Itraconazol Universal Farma 100 mg
  Universal Farma, Austria
• Itraconazol Winthrop
  Zentiva Pharma, Germany
• Itraconazol-CT
  AbZ-Pharma, Germany
• Itraconazole
  Accord Healthcare, United States; Actavis UK, United Kingdom; Alembic, United States; Alkem, United States; Amneal Pharmaceuticals, United States; Beacon Pharmaceuticals, United Kingdom; Concordia, United Kingdom; Jubilant Generics, United States; Kaken Seiyaku, Japan; Mylan, United States; Nichi-Iko Pharmaceutical, Japan; Par Pharmaceutical, United States; Sandoz, United Kingdom; Sandoz, United States; Sawai Seiyaku, Japan; Zydus Pharma, United States
• Itraconazole 100
  Kobayashi Kako, Japan
• Itraconazole 200
  Kobayashi Kako, Japan
• Itraconazole 50
  Kobayashi Kako, Japan
• Itraconazole Central Procurement
  Central Procurement & Supplies Unit, Malta
• Itraconazole EG
  Eurogenerics, Belgium
• Itraconazole EMS
  EMS, Brazil
• Itraconazole Eurofarma
  Eurofarma, Brazil
• Itraconazole Glenmark
  Glenmark, Malta
• Itraconazole Mylan
  Mylan, Belgium; Mylan, France
• Itraconazole P & D
  P & D, Malta
• Itraconazole Sandoz
  Sandoz, Belgium; Sandoz, France
• Itraconazole Syri
  Syri, Malta
• Itraconazole Teva
  Teva Pharma Belgium, Belgium; Teva Santé, France
• Itraconazole UD 1%
  Nippon Zoki Seiykau, Japan
• Itraconazole-Premier Research Sandoz
  Sandoz, Poland
• Itraconazol-Mepha 100mg
  Mepha Pharma, Switzerland
• Itraconazolo Doc Generici
  DOC Generici, Italy
• Itraconazolo EG
  EG, Italy
• Itraconazolo Mylan Generics
  Mylan, Italy
• Itraconazolo Premiere Research
  Premier Research, Italy
• Itraconazolo Ratiopharm
  ratiopharm Italia, Italy
• Itraconazolo Sandoz
  Sandoz, Italy
• Itraconazolo Teva
  Teva Italia, Italy
• Itraconazol-ratiopharm
  ratiopharm, Germany
• Itraconazol-Ratiopharm 100mg
  Ratiopharm, Luxembourg; Teva, Hungary
• Itraconep
  ExtractumPharma, Serbia
• Itracosid
  Grupo Carbel, Mexico
• Itraderm
  Dermapharm, Germany
• Itraderm 100 mg
  Dermapharm, Austria; Dermapharm, Switzerland
• Itrafung
  Siegfried, Ecuador
• Itrafungex
  Utopia, Egypt
• Itrafungol [veterinary use]
  Elanco Animal Health, Ireland; Elanco Animal Health, Norway; Elanco Animal Health, Sweden; Elanco Animal Health, United States; Elanco Deutschland GmbH, Germany; Elanco Eläinlääkkeet, Finland; Elanco Tiergesundheit AG, Switzerland; Eli Lilly Benelux, Belgium; Janssen-Cilag, Italy; Lilly, United Kingdom
• Itrafungol 10 mg/ml [veterinary use]
  Lilly Vet, France; Lilly-Elanco, Netherlands
• Itrafungol 10 mg/ml Für Katzen [veterinary use]
  Elanco Animal Health, Austria
• ItraGen
  Generics, Poland
• Itragerm
  Isdin, Spain
• Itraisdin
  ISDIN, Germany
• Itrakonazol Actavis
  Actavis, Sweden
• Itrakonazol PharmaS
  PharmaS, Croatia (Hrvatska)
• Itrakonazol Pliva
  Pliva, Croatia (Hrvatska)
• Itrakonazol Slaviamed
  Slaviamed, Bosnia & Herzegowina
• Itrakonazol STADA
  PharmaCoDane, Sweden
• Itramicol
  AC Farma, Peru
• Itranax
  Janssen-Cilag, Mexico
• Itranazole
  Adipharm, Bulgaria
• Itranex
  Dermagen, Pakistan
• Itranol
  Liconsa, Israel; Olainfarm, Bosnia & Herzegowina
• Itranols
  Olainfarm, Latvia
• Itranox
  Adwia, Egypt; Generic Partners, Australia
• Itranstad
  STADA, Hong Kong; Stada-VN JV, Vietnam
• Itrapex
  Apex, Egypt
• Itraproton
  Epsilon, Greece; Proton Pharma, Greece
• Itrasec [+ Secnidazole]
  Elipesa, Dominican Republic; Elipesa, El Salvador
• Itrasix
  Sinensix Pharma, Thailand
• Itraspor
  Difare, Ecuador; Johnson & Johnson, Turkey; Sigma Pharma Nature's Plus Farm. Ltda., Brazil
• Itraviron
  Farmedia, Greece
• Itrax
  Axxon, Poland
• Itraxyl
  Keymen, Turkey
• Itrazile
  S.C. Slavia Pharma, Georgia
• Itrazol
  ADWYA, Tunisia; Medrock, Peru; Saja, Lebanon; Verisfield, Greece; Vertex, Russian Federation
• Itrazol 100mg
  Saudi Arabian Japanese Pharmaceuticals SAJA, Oman
• Itrazole
  Hwang's, Taiwan; Millimed, Thailand; Mylan, New Zealand; Z-Jans Pharma, Pakistan
• Itrizole 1%
  Janssen Pharmaceutical, Japan
• Itrizole 50
  Janssen Pharmaceutical, Japan
• Itrokast
  Axxon, Poland
• Itrol
  Suiphar, Dominican Republic
• Itzol
  Lapi Laboratories, Indonesia
• I-Zol
  Popular, Bangladesh
• Kanazol
  Slaviamed, Serbia
• Konitra
  Kolon, South Korea
• Kupitral
  Korea United Pharm., Vietnam
• Lozanoc
  Mayne Pharma, Australia
• Lozartil
  Novag, Mexico
• Mei Fu
  Lisheng Pharmaceutical, China
• Mesmor
  Rafarm, Greece
• Micogal
  Rompharm Company, Romania
• Miconal
  Diffucap-Chemo, Brazil
• Micoral
  Mediderm, Peru
• Micotenk
  Biotenk, Argentina
• Micronazol
  Hospira UK Ltd, Greece
• Mint-Itraconazole
  Mint Pharmaceuticals, Canada
• Mycotrazol
  Galenium Pharmasia Laboratories, Indonesia
• Mylan Itraconazole
  Mylan, South Africa
• Neo-Candimyk
  Viofar, Greece
• Neozol
  Iqfarma, Peru
• Niddazol
  STADA Nordic, Denmark
• Nitridazol
  HLB Pharma, Argentina
• Nufatrac
  Nufarindo, Indonesia
• Omicral
  Medico Uno, Serbia; PharmaSwiss Ceska, Romania
• Omicral 100 mg
  IPR Beta Pharma, Hungary
• Onicozol
  Pharmetica, Paraguay
• Onmel
  Sebela Pharmaceuticals, United States
• Orungal
  Janssen Pharmaceutica, Bulgaria; Janssen-Cilag, Lithuania; Janssen-Cilag, Macedonia; Janssen-Cilag, Poland; Janssen-Cilag International, Romania
• Orungal 100 mg
  Janssen, Hungary
• Orzol
  Dutriec, Paraguay
• Panastat
  Panalab, Argentina
• Panastat 200
  Panalab, Argentina
• Petrazole
  Pharos, Indonesia
• Pharmaniaga Itraconazole
  Pharmaniaga, Hong Kong
• Prokanazol
  Liconsa, Slovakia; Pro.Med.CS, Czech Republic; PRO.MED.CS Baltic, Estonia
• Quali-Itrazole
  Quality Pharm, Hong Kong
• Rixtal
  Biomep, Mexico
• Salimidin
  Raymos, Argentina
• Salimidin 200
  Raymos, Argentina
• Sempera
  Janssen-Cilag, Germany
• Sempera 10mg/ml
  Janssen-Cilag, Germany
• Sempera 7
  Janssen-Cilag, Germany
• Sepia [+ Secnidazole]
  Wermar, Mexico
• Silicsan
  Rayere, Mexico
• Sinozol
  Best, Mexico
• SIROS
  Janssen-Cilag, Germany
• Spazol
  Siam Bheasach, Thailand
• Sporacid
  Dexa Medica, Myanmar; Dexa Medica, Vietnam; Ferron, Indonesia
• Sporadal
  Harsen, Indonesia
• Sporal
  Janssen, Thailand; Janssen-Cilag, Malta; Janssen-Cilag, Vietnam; Janssen-Cilag International, Cyprus; Janssen-Cilag Ltd, Myanmar
• Sporanox
  Central Procurement & Supplies Unit, Malta; Janssen, Canada; Janssen, Chile; Janssen, Denmark; Janssen, Finland; Janssen, Hong Kong; Janssen, Ireland; Janssen, Lebanon; Janssen, Malaysia; Janssen, Norway; Janssen, New Zealand; Janssen, Philippines; Janssen, Sweden; Janssen, Singapore; Janssen, Slovakia; Janssen, Taiwan; Janssen, Venezuela; Janssen, South Africa; Janssen Cilag, Argentina; Janssen Cilag, Paraguay; Janssen Pharma, United States; Janssen-Cilag, Australia; Janssen-Cilag, Belgium; Janssen-Cilag, Brazil; Janssen-Cilag, Colombia; Janssen-Cilag, Czech Republic; Janssen-Cilag, Ecuador; Janssen-Cilag, Egypt; Janssen-Cilag, Spain; Janssen-Cilag, France; Janssen-Cilag, United Kingdom; Janssen-Cilag, Greece; Janssen-Cilag, Italy; Janssen-Cilag, Kuwait; Janssen-Cilag, Mexico; Janssen-Cilag, Peru; Janssen-Cilag, Portugal; Janssen-Cilag, Uruguay; Janssen-Cilag, Vietnam; Janssen-Cilag AB, Iceland; Janssen-Cilag International, Cyprus; J-C Healthcare, Israel; Johnson & Johnson, Indonesia; Johnson & Johnson, India; Johnson & Johnson, Lithuania; Johnson & Johnson, Turkey; Xian Janssen, China
• Sporanox 100mg
  Janssen, Luxembourg; Janssen-Cilag, Switzerland; Janssen-Cilag, Oman; Janssen-Cilag Pharma, Austria
• Sporanox 10mg/ml
  Janssen, Luxembourg; Janssen-Cilag, Switzerland; Janssen-Cilag Pharma, Austria
• Sporanox Derm 100mg
  Janssen-Cilag Pharma, Austria
• Sporanox G
  Janssen-Cilag, Switzerland
• Sporasec
  Janssen-Cilag, Peru
• Sporasec [+ Secnidazole]
  Janssen, Venezuela; Janssen Cilag, Paraguay; Janssen-Cilag, Colombia; Janssen-Cilag, Mexico
• Sporax
  Dexa Medica, Indonesia
• Sporex
  Toprak, Turkey
• Sporizole
  Target Pharma, Greece
• Spornar
  Charoen Bhaesaj Lab, Thailand
• Spyrocon
  Interbat, Indonesia
• Steitraz
  Landsteiner, Mexico
• Sterginox
  Novofarm, Greece
• Teramic
  Laboratorios Andromaco, Chile
• Trachon
  Bernofarm, Indonesia
• Tracon
  Spimaco, Lebanon
• Tracor
  Pharmacore Laboratories, Indonesia
• Tranizolo
  EG, Italy
• Tranlex
  Dispert, Uruguay
• Trax-100
  Arlex, Mexico
• Traxonol
  GeoLab, Brazil
• Trazer
  Boniscontro & Gazzone, Italy
• Triasporin
  Italfarmaco, Italy
• Trioxal
  Polpharma, Poland
• Trisporal
  Euro Registratie, Netherlands; Janssen, South Africa; Janssen-Cilag, Netherlands
• Unitrac
  Dankos, Malaysia; Dankos, Singapore; Kalbe, Indonesia
• Vanoran
  Glomed Pharmaceutical Company, Vietnam
• Yi Qi Kang
  Bei Te Pharm, China

Glossary

Further information on drug naming conventions: International Nonproprietary Names.