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Home > Drugs > Lysosomal enzymes > Kanuma
Lysosomal enzymes

Kanuma

https://themeditary.com/drug/kanuma-3841.html
Medically Reviewed by Glamora Samuels, MD TheMediTary.Com | Reviewed: Aug 04, 2023  Additional Content by TheMediTary.Com

Generic name: sebelipase alfa [ se-be-lye-pase-al-fa ]

Drug class: Lysosomal enzymes

Dosage form: injection, solution, concentrate

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Sebelipase alfa

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Kanuma?

Kanuma is a copy of an enzyme that is normally produced in the body to help break down fats and keep them from building up in your cells.

Kanuma is used to treat lysosomal acid lipase deficiency. This is a life-threatening genetic disorder that can damage major organs in the body and lead to early death. This medicine replaces the missing enzyme when the body does not have enough of its own.

Kanuma may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

How should I use Kanuma

Kanuma is injected into a vein through an IV. A healthcare provider will give you this injection.

Kanuma is usually given once every other week. The IV infusion must be given slowly and can take 1 to 2 hours to complete.

You will be watched closely during and after receiving Kanuma, to make sure you do not have an allergic reaction to the medication.

Tell your doctor if you have any changes in weight. Kanuma doses are based on weight (especially in children), and any changes may affect the dose.

Detailed Kanuma dosage information
Kanuma Dosage information (more detail)

Before Taking

You should not be treated with Kanuma if you are allergic to it.

To make sure Kanuma is safe for you, tell your doctor if you have:

  • an allergy to eggs or egg products.

It is not known whether Kanuma will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether sebelipase alfa passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Kanuma is not approved for use by anyone younger than 1 month old.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Kanuma.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Kanuma?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Kanuma side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver right away if you feel itchy, flushed, chilled or feverish, or if you have a runny nose, eye irritation, diarrhea, chest discomfort, or trouble breathing.

Kanuma may cause serious side effects. Call your doctor at once if you have:

  • severe skin rash, itching, or swelling;

  • agitation, irritability;

  • stomach pain; or

  • low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating.

Common side effects of Kanuma may include:

  • fever, weakness;

  • runny nose, sinus pain, sore throat, cough;

  • rash;

  • diarrhea, constipation;

  • nausea, vomiting; or

  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Kanuma Side Effects

More about Kanuma (Sebelipase alfa [ se-be-lye-pase-al-fa ])

Dosage information
Kanuma Side Effects
During pregnancy
Kanuma Prescribing Information
Drug images
Side effects
Drug class: Lysosomal enzymes

Related treatment guides

Lysosomal Acid Lipase Deficiency
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions
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