Generic name: Donanemab
Pregnancy & Lactation: Risk data not available
What is Kisunla?
Donanemab is used to treat adults with Alzheimer's disease.
Donanemab may also be used for purposes not listed in this medication guide.
Warnings
You should not receive donanemab if you are allergic to it.
Donanemab can cause a condition called amyloid related imaging abnormalities (ARIA).
ARIA is a temporary swelling or small spots of bleeding in the brain that usually clear up with time. Your doctor may perform an MRI (magnetic resonance imaging) of your brain before and during your treatment with donanemab. Ask your doctor about your risk.
It is not known if donanemab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
How should I use Kisunla
Use Kisunla (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets.
Donanemab is given slowly over 30 minutes as an infusion into a vein, usually once every 4 weeks. A healthcare provider will give you this injection.
Your doctor will perform tests to make sure donanemab is the right treatment for you.
You may be given other medications to help prevent serious side effects or allergic reaction.
Wear a medical alert tag or carry an ID card to let others know you use donanemab.
Store this medicine in the original container in the refrigerator away from moisture, heat, and light. Do not freeze.
You may store the medicine for up to 3 days at room temperature.
You may store the diluted solution for up to 12 hours at room temperature, or up to 72 hours in a refrigerator, including the infusion time.
Call your doctor for instructions if you miss an appointment for your donanemab injection.
Kisunla side effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Donanemab can cause temporary swelling or bleeding in the brain, especially if you use medication to prevent blood clots.
Call your doctor if you have:
- dizziness, confusion, headache;
- vision changes;
- seizures;
- nausea; or
- trouble walking.
Common side effects may include:
- ARIA with symptoms, or with signs that appear on an MRI; or
- headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Kisunla?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.