Linezolid is an antibiotic that fights bacteria in the body. Linezolid is also an MAO (monoamine oxidase) inhibitor.

Linezolid is used to treat different types of bacterial infections, such as pneumonia, skin infections, and infections that are resistant to other antibiotics.

Linezolid may also be used for purposes not listed in this medication guide.

You should not use linezolid if you are allergic to it.

Do not use linezolid if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with linezolid could cause a serious condition called serotonin syndrome.

Tell your doctor if you have ever had:

• high blood pressure;
• a thyroid disorder;
• a carcinoid tumor;
• bone marrow suppression or a weak immune system;
• kidney or liver disease;
• pheochromocytoma (adrenal gland tumor);
• diabetes;
• seizures; or
• if you use a catheter.

Tell your doctor if you are pregnant or breastfeeding.

If you are breastfeeding, tell your doctor if you notice diarrhea or vomiting in the nursing baby.

Linezolid liquid may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

Use Linezolid (Oral/Injection)(Intravenous,Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

• vision problems, changes in color vision;
• severe stomach pain, diarrhea that is watery or bloody;
• a seizure;
• sweating, feeling anxious or shaky (may be signs of low blood sugar);
• lactic acidosis--unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired; or
• low blood cell counts--fever, chills, tiredness, weakness, confusion, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects may include:

• nausea, vomiting, diarrhea;
• rash;
• anemia (low red blood cells); or
• headache, dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Avoid taking anti-diarrhea medicine without first asking your doctor. Diarrhea may be a sign of a new infection.

Eating tyramine while you are using linezolid can raise your blood pressure to dangerous levels. Avoid foods that have a high level of tyramine, such as:

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You should be very familiar with the list of foods you must avoid while you are using linezolid.