Lotrimin AF is an antifungal medication. This medicine prevents fungus from growing on your skin.

Lotrimin AF (for the skin) is used to treat skin infections such as athlete's foot, jock itch, ringworm, tinea versicolor (a fungus that discolors the skin), and yeast infections of the skin.

Lotrimin AF may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Lotrimin AF is for use only on the skin. Do not use this medicine on open wounds.

Lotrimin AF is not for use in the vagina or rectum.

Wash your hands before and after using this medication, unless you are treating a skin condition on your hands.

Clean and dry the affected area. Apply the cream, lotion, spray, or powder once or twice daily as directed for 2 to 4 weeks.

Do not cover the treated skin area unless your doctor tells you to. A light cotton-gauze dressing may be used to protect clothing.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antifungal medicine.

Call your doctor if the infection does not clear up in 2 weeks (or 4 weeks for athlete's foot), or if it appears to get worse.

Store at room temperature away from moisture and heat. Keep the tube tightly closed when not in use.

You should not use Lotrimin AF if you are allergic to miconazole.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:

• if you are using a blood thinner such as warfarin, Coumadin, Jantoven.

It is not known whether Lotrimin AF will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

It is not known whether miconazole topical passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Avoid getting this medication in your eyes, nose, or mouth.

Avoid wearing tight-fitting, synthetic clothing that doesn't allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until the infection is healed.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Lotrimin AF may cause serious side effects. Stop using Lotrimin AF and call your doctor at once if you have:

• severe blistering, redness, or irritation of treated skin.

Common side effects of Lotrimin AF may include:

• itching, peeling, or dry skin.

Although the risk of serious side effects is low when Lotrimin AF is applied to the skin, side effects can occur if the medicine is absorbed into your bloodstream, including:

• dry mouth, sore tongue, tooth pain, red or swollen gums;

• altered sense of taste;

• nausea, diarrhea; or

• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

It is not likely that other drugs you take orally or inject will have an effect on topically applied miconazole. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.