Betamethasone is highly potent steroid that reduces itching, swelling, and redness of the skin.

Clotrimazole is an antifungal medication that fights infections caused by fungus.

Betamethasone and clotrimazole topical (for the skin) is a combination medicine used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm.

Betamethasone and clotrimazole topical may also be used for purposes not listed in this medication guide.

You may not be able to use this medicine if you are allergic to betamethasone or clotrimazole, or if you have ever had an allergic reaction to:

• other steroid medicines (such as dexamethasone, fludrocortisone, hydrocortisone, prednisone, triamcinolone, and others); or
• other antifungal medicines (such as itraconazole, ketoconazole, miconazole, posaconazole, or voriconazole).

Tell your doctor if you have ever had:

• a skin reaction to any steroid medicine;
• cataract or glaucoma;
• liver disease; or
• an adrenal gland disorder.

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

Using highly potent steroid medicine during pregnancy may increase the risk of low birthweight in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply betamethasone and clotrimazole to your chest, avoid areas that may come into contact with the baby's mouth.

If you are pregnant or breastfeeding, apply this medicine to the smallest skin area and for the shortest amount of time possible to treat your condition.

This medicine is not approved for use by anyone younger than 17 years old. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

Use Lotrisone (Topical) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects may include:

• numbness, tingling, or stinging;
• skin dryness or rash;
• swelling; or
• new infections.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Avoid getting this medicine in your eyes, mouth, or vagina.

Do not use betamethasone and clotrimazole topical to treat any skin condition that has not been checked by your doctor.

Avoid using other topical steroid medications on the areas you treat with betamethasone and clotrimazole, unless your doctor tells you to.