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Home > Drugs > Urinary anti-infectives > Macrobid
Urinary anti-infectives

Macrobid

https://themeditary.com/drug/macrobid-528.html
Medically Reviewed by Sanjai Sinha, MD TheMediTary.Com | Reviewed: Jul 11, 2023  Additional Content by TheMediTary.Com

Generic name: nitrofurantoin [ nye-troe-fue-ran-toin ]

Drug class: Urinary anti-infectives

Dosage form: capsule

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Macrodantin, Nitrofurantoin

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ
  • Macrobid (Nitrofurantoin [ nye-troe-fue-ran-toin ])-Macrobid Norwich Eaton-100 mg-Black & Yellow-Capsule-shape Macrobid 100 mg (Macrobid Norwich Eaton)
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What is Macrobid?

Macrobid is an antibiotic that fights bacteria in the body.

Macrobid is used to treat urinary tract infections.

Macrobid may also be used for purposes not listed in this medication guide.

Warnings

You should not take Macrobid if you have severe kidney disease, urination problems, or a history of jaundice or liver problems caused by nitrofurantoin.

Do not take Macrobid if you are in the last 2 to 4 weeks of pregnancy.

Before taking this medicine

You should not take Macrobid if you are allergic to nitrofurantoin, or if you have:

  • severe kidney disease;

  • a history of jaundice or liver problems caused by taking nitrofurantoin;

  • if you are urinating less than usual or not at all; or

  • if you are in the last 2 to 4 weeks of pregnancy.

Do not take Macrobid if you are in the last 2 to 4 weeks of pregnancy.

To make sure Macrobid is safe for you, tell your doctor if you have:

  • kidney disease;

  • anemia;

  • diabetes;

  • an electrolyte imbalance or vitamin B deficiency;

  • glucose-6-phosphate dehydrogenase (G6PD) deficiency; or

  • any type of debilitating disease.

FDA pregnancy category B. Macrobid is not expected to be harmful to an unborn baby during early pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Nitrofurantoin can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking Macrobid.

Macrobid should not be given to a child younger than 1 month old.

Macrobid pregnancy and breastfeeding warnings (more detail)

How should I take Macrobid

Take Macrobid exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Macrobid with food.

Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

You may mix your liquid dose with water, milk, or fruit juice to make it easier to swallow. Drink the entire mixture right away.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Macrobid will not treat a viral infection such as the common cold or flu.

Macrobid is usually given for 5 days in females and 7 days in males for uncomplicated UTI.

If you use this medicine long-term, for prevention of UTI, you may need frequent medical tests at your doctor's office.

Macrobid can cause unusual results with certain lab tests for glucose (sugar) in the urine. Tell any doctor who treats you that you are using Macrobid.

Store at room temperature away from moisture, heat, and light.

Dosing information

Usual Adult Dose for Cystitis:

Regular release: 50 to 100 mg orally 4 times a day for 1 week or for at least 3 days after urine sterility is obtained
Dual release: 100 mg orally twice a day for 7 days

Usual Adult Dose for Cystitis Prophylaxis:

Regular release: 50 to 100 mg orally once a day at bedtime

Usual Pediatric Dose for Cystitis:

Regular release:
1 month or older: 5 to 7 mg/kg/day (up to 400 mg/day) orally in 4 divided doses

Dual release:
Greater than 12 years: 100 mg orally twice a day for 7 days

Usual Pediatric Dose for Cystitis Prophylaxis:

Regular release:
1 month or older: 1 to 2 mg/kg/day (up to 100 mg/day) orally in 1 to 2 divided doses

Detailed Macrobid dosage information
Macrobid Dosage information (more detail)

Before Taking

You should not take Macrobid if you are allergic to nitrofurantoin, or if you have:

  • severe kidney disease;

  • a history of jaundice or liver problems caused by taking nitrofurantoin;

  • if you are urinating less than usual or not at all; or

  • if you are in the last 2 to 4 weeks of pregnancy.

Do not take Macrobid if you are in the last 2 to 4 weeks of pregnancy.

To make sure Macrobid is safe for you, tell your doctor if you have:

  • kidney disease;

  • anemia;

  • diabetes;

  • an electrolyte imbalance or vitamin B deficiency;

  • glucose-6-phosphate dehydrogenase (G6PD) deficiency; or

  • any type of debilitating disease.

FDA pregnancy category B. Macrobid is not expected to be harmful to an unborn baby during early pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Nitrofurantoin can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking Macrobid.

Macrobid should not be given to a child younger than 1 month old.

Macrobid pregnancy and breastfeeding warnings (more detail)

Related/similar drugs

amoxicillin, doxycycline, ciprofloxacin, cephalexin, Augmentin, levofloxacin, ceftriaxone

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Macrobid?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Avoid using antacids without your doctor's advice. Use only the type of antacid your doctor recommends. Some antacids can make it harder for your body to absorb nitrofurantoin.

Macrobid side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Macrobid: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • diarrhea that is watery or bloody;

  • sudden chest pain or discomfort, wheezing, dry cough or hack;

  • new or worsening cough, trouble breathing;

  • fever, chills, body aches, tiredness, unexplained weight loss;

  • numbness, tingling, or pain in your hands or feet;

  • liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

  • lupus-like syndrome--joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color.

Serious side effects may be more likely in older adults and those who are ill or debilitated.

Common Macrobid side effects may include:

  • headache, dizziness;

  • gas, upset stomach;

  • mild diarrhea; or

  • vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Macrobid Side Effects

What other drugs will affect Macrobid?

Other drugs may interact with nitrofurantoin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What to Expect

You should feel better within a few days of taking nitrofurantoin. Tell your doctor if you don’t notice an improvement after three days.

It’s important to keep taking this medicine for the full course of treatment, even if you feel better. Stopping it too soon can cause your infection to come back.

Additional Dosage Information

Your dosage will depend on your medical condition, the formulation you use, and other factors.

Secondary Uses

Nitrofurantoin is sometimes used to treat conditions not listed in this guide. For instance, some doctors prescribe it “off-label” to treat bacteria found in the urine during pregnancy that doesn’t cause symptoms.

Popular FAQ

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More about Macrobid (Nitrofurantoin [ nye-troe-fue-ran-toin ])

Dosage information
Macrobid Side Effects
During pregnancy
Macrobid Prescribing Information
Drug images
Side effects
Drug class: Urinary anti-infectives

Related treatment guides

Urinary Tract Infection
Bladder Infection
Prevention of Bladder infection (Cystitis Prophylaxis)
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ
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