Pregnancy & Lactation: Risk data not available
What is Mafenide Topical?
Mafenide is an antibiotic that fights bacteria in the body.
Mafenide topical (for the skin) is used to prevent infection in severe burn wounds.
Mafenide may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you are allergic to mafenide.
To make sure mafenide topical is safe for you, tell your doctor if you have:
- kidney disease;
- a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;
- asthma or sulfite allergy; or
- if you are allergic to sulfa drugs.
FDA pregnancy category C. It is not known whether mafenide topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether mafenide topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
How should I use Mafenide Topical
Use Mafenide Topical (Topical) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor will determine the correct amount and type of mafenide to use. You will receive this medication in a hospital or burn unit setting.
Mafenide cream is usually applied to the burn wound once or twice a day. The wound should be kept covered with this medicine at all times during treatment.
Mafenide powder is usually mixed together with a saline solution and applied over a gauze dressing using a syringe or irrigation tube. Mafenide is usually applied several times per day in order to keep the bandaging wet.
Because you will receive mafenide topical in a clinical setting, you are not likely to miss a dose.
Mafenide Topical side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers right away if you have:
- pale or yellowed skin, dark colored urine, fever, confusion or weakness;
- rapid breathing;
- skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or
- severe skin irritation where the medicine is applied.
Common side effects may include:
- rash, redness, blistering, or itching of treated skin;
- pain or burning of treated skin; or
- white or "pruned" appearance of the skin (caused by leaving wound dressings on for long periods of time).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Mafenide Topical?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.