By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Progestins > Makena auto-injector
Progestins

Makena auto-injector

https://themeditary.com/drug/makena-auto-injector-2222.html
Medically Reviewed by Glamora Samuels, MD TheMediTary.Com | Reviewed: Jul 13, 2023  Additional Content by TheMediTary.Com

Generic name: hydroxyprogesterone injection [ hye-drox-ee-pro-jes-te-rone ]

Drug class: Progestins

Dosage form: injection

Availability: Discontinued

Pregnancy & Lactation: Risk data available

Brand names: Makena, Hydroxyprogesterone injection

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Makena auto-injector?

Hydroxyprogesterone is a form of progestin, a manmade form of a female hormone called progesterone.

Hydroxyprogesterone is used to lower the risk of premature birth in a woman who has already had one premature baby. Hydroxyprogesterone will not stop premature labor that has already begun.

Hydroxyprogesterone is not for use in women who are pregnant with more than one baby (twins, triplets, etc).

Hydroxyprogesterone may also be used for purposes not listed in this medication guide.

Warnings

You should not use Makena Auto-Injector if you have: uncontrolled high blood pressure, unusual vaginal bleeding, liver disease or liver cancer, jaundice caused by your pregnancy, or if you have ever had circulation problems, a stroke or blood clot, or cancer of the breast, uterus/cervix, or vagina.

How should I use Makena auto-injector

Hydroxyprogesterone is injected under the skin or into a muscle.

A healthcare provider will give you this injection.

The first Makena Auto-Injector is usually given during the second trimester of pregnancy. The usual dosing schedule is one injection per week until the 37th week or until your baby is born. Follow your doctor's instructions.

Your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments. Every woman should remain under the care of a doctor during pregnancy.

Detailed Makena dosage information
Makena auto-injector Dosage information (more detail)

Before Taking

You should not be treated with this medicine if you are allergic to hydroxyprogesterone or castor oil, or if you have:

  • unusual vaginal bleeding that is not related to your pregnancy;

  • severe or uncontrolled high blood pressure;

  • liver disease or liver cancer;

  • jaundice caused by your pregnancy;

  • a history of cancer of the breast, uterus/cervix, or vagina; or

  • a history of a stroke, blood clot, or circulation problems.

Hydroxyprogesterone is not approved for use by anyone younger than 16 years old.

Tell your doctor if you have ever had:

  • eclampsia or preeclampsia of pregnancy;

  • kidney disease;

  • high blood pressure, heart disease;

  • migraine headaches;

  • diabetes (in you or a family member);

  • epilepsy or other seizure disorder;

  • asthma; or

  • depression.

It is not known whether hydroxyprogesterone will prevent any medical problems in a newborn baby. Talk to your doctor about your baby's individual risk.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Makena Auto-Injector.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Makena auto-injector?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Makena auto-injector side effects

Get emergency medical help if you have signs of an allergic reaction: hives, itching; difficulty breathing; swelling of your face, lips, tongue, or throat.

Makena Auto-Injector may cause serious side effects. Call your doctor at once if you have:

  • swelling, oozing, bleeding, or worsening pain where the injection was given;

  • jaundice (yellowing of the skin or eyes);

  • symptoms of depression (sleep problems, weakness, mood changes);

  • swelling in your hands, ankles, or feet;

  • increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed; or

  • signs of a blood clot--sudden numbness or weakness, problems with vision or speech, swelling or redness in an arm or leg.

Common side effects of Makena Auto-Injector may include:

  • pain, swelling, itching, rash, or a lump where the medicine was injected;

  • nausea; or

  • diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Makena auto-injector Side Effects

What other drugs will affect Makena auto-injector?

Other drugs may affect hydroxyprogesterone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

More about Makena auto-injector (Hydroxyprogesterone injection [ hye-drox-ee-pro-jes-te-rone ])

Dosage information
Makena auto-injector Side Effects
During pregnancy
Drug images
Side effects
Drug class: Progestins

Related treatment guides

Premature Labor
Share this Article
Contents
Uses Warnings Before Taking Dosage Side effects Interactions
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by